Maria Secrier
@mariasecrier.bsky.social
Cancer genomics, cellular plasticity, tumour microenvironment, digital pathology | Associate Professor and Group Leader @UCL | PhD from @EMBL | opinions my own
https://secrierlab.github.io/
https://secrierlab.github.io/
Pinned
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
October 7, 2025 at 7:46 PM
How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
September 19, 2025 at 12:15 PM
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
Reposted by Maria Secrier
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
September 18, 2025 at 8:02 PM
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology.
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org
August 12, 2025 at 5:54 PM
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
Reposted by Maria Secrier
🚨 We’re hiring a Postdoc!
Join our osteosarcoma research project @mariasecrier.bsky.social @fionafreeman.bsky.social. Funded by @littleprincesses.bsky.social 🧬🧫
🔹Cellular & molecular biology
🔹Cool 3D models
📍 UCL Cancer Institute, London
🗓️ July 1
📎 bit.ly/4kBCPt3
🌐 More info: lnkd.in/eahvf7Tg
Join our osteosarcoma research project @mariasecrier.bsky.social @fionafreeman.bsky.social. Funded by @littleprincesses.bsky.social 🧬🧫
🔹Cellular & molecular biology
🔹Cool 3D models
📍 UCL Cancer Institute, London
🗓️ July 1
📎 bit.ly/4kBCPt3
🌐 More info: lnkd.in/eahvf7Tg
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
bit.ly
June 9, 2025 at 10:18 PM
🚨 We’re hiring a Postdoc!
Join our osteosarcoma research project @mariasecrier.bsky.social @fionafreeman.bsky.social. Funded by @littleprincesses.bsky.social 🧬🧫
🔹Cellular & molecular biology
🔹Cool 3D models
📍 UCL Cancer Institute, London
🗓️ July 1
📎 bit.ly/4kBCPt3
🌐 More info: lnkd.in/eahvf7Tg
Join our osteosarcoma research project @mariasecrier.bsky.social @fionafreeman.bsky.social. Funded by @littleprincesses.bsky.social 🧬🧫
🔹Cellular & molecular biology
🔹Cool 3D models
📍 UCL Cancer Institute, London
🗓️ July 1
📎 bit.ly/4kBCPt3
🌐 More info: lnkd.in/eahvf7Tg
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
[Preprint alert]
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
June 2, 2025 at 12:30 PM
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
Reposted by Maria Secrier
Are you looking for a postdoc position in #SpatialBiology?
We're advertising roles in both mathematical method development and in spatial data analysis @ox.ac.uk in colorectal precancer spatial biology!
Method Development: tinyurl.com/4vcbdjcy 🧮
Data Interpretation: tinyurl.com/yzsp729s 🧪
We're advertising roles in both mathematical method development and in spatial data analysis @ox.ac.uk in colorectal precancer spatial biology!
Method Development: tinyurl.com/4vcbdjcy 🧮
Data Interpretation: tinyurl.com/yzsp729s 🧪
Job Details
my.corehr.com
April 14, 2025 at 9:55 AM
Are you looking for a postdoc position in #SpatialBiology?
We're advertising roles in both mathematical method development and in spatial data analysis @ox.ac.uk in colorectal precancer spatial biology!
Method Development: tinyurl.com/4vcbdjcy 🧮
Data Interpretation: tinyurl.com/yzsp729s 🧪
We're advertising roles in both mathematical method development and in spatial data analysis @ox.ac.uk in colorectal precancer spatial biology!
Method Development: tinyurl.com/4vcbdjcy 🧮
Data Interpretation: tinyurl.com/yzsp729s 🧪
Reposted by Maria Secrier
In addition to the two #SpatialBiology posts in the thread below, we're now also advertising for a Research Software Engineer #RSE to help us take #MuSpAn to the next level - come and join us!
my.corehr.com/pls/uoxrecru...
#academic #jobs #softwaredeveloper #compsci
my.corehr.com/pls/uoxrecru...
#academic #jobs #softwaredeveloper #compsci
May 1, 2025 at 2:15 PM
In addition to the two #SpatialBiology posts in the thread below, we're now also advertising for a Research Software Engineer #RSE to help us take #MuSpAn to the next level - come and join us!
my.corehr.com/pls/uoxrecru...
#academic #jobs #softwaredeveloper #compsci
my.corehr.com/pls/uoxrecru...
#academic #jobs #softwaredeveloper #compsci
Attending #AACR2025 and interested in new ways of applying AI to make sense of single-cell and spatial omics data? Come hear me talk about our methods today at 5:15 pm in the "Accelerating Cancer Research with AI and Data Science Session" or connect with me afterwards.
April 25, 2025 at 1:57 PM
Attending #AACR2025 and interested in new ways of applying AI to make sense of single-cell and spatial omics data? Come hear me talk about our methods today at 5:15 pm in the "Accelerating Cancer Research with AI and Data Science Session" or connect with me afterwards.
Reposted by Maria Secrier
Dear @guigau.bsky.social and co-authors. Please see our very similar paper (not cited in yours as far as I can see) published 2018. Our software is called Croco!!! A citation would be nice!!!
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
January 23, 2025 at 11:07 AM
Dear @guigau.bsky.social and co-authors. Please see our very similar paper (not cited in yours as far as I can see) published 2018. Our software is called Croco!!! A citation would be nice!!!
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
New insights into the role of p21 in lung cancer from the fantastic @alexisbarr.bsky.social!
New Year, new paper! (Ok, it actually came out just before Christmas but who was working then?!)
Here we show that p21 promotes the survival of non-small cell lung cancer cells, under normal growth & after chemotherapy: rdcu.be/d4kvU
Here we show that p21 promotes the survival of non-small cell lung cancer cells, under normal growth & after chemotherapy: rdcu.be/d4kvU
Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
British Journal of Cancer - Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
rdcu.be
January 2, 2025 at 1:19 PM
New insights into the role of p21 in lung cancer from the fantastic @alexisbarr.bsky.social!
Delighted to introduce our new spatial transcriptomics tool, SpottedPy, allowing the identification of tumour hotspots at different scales and the exploration of distances and overlap with tumour microenvironment niches: genomebiology.biomedcentral.com/articles/10....
December 2, 2024 at 12:00 PM
Delighted to introduce our new spatial transcriptomics tool, SpottedPy, allowing the identification of tumour hotspots at different scales and the exploration of distances and overlap with tumour microenvironment niches: genomebiology.biomedcentral.com/articles/10....
Reposted by Maria Secrier
As a member of @smbmathbiology.bsky.social (and podcast fan) I listen to all of these, best way to keep up with the #science and the #scientists in #MathBio other than those I usually obsess about #MathOnco #MathEvo
I suppose now is a good time to introduce #BiologyInNumbers, a #SciComm podcast I have the pleasure of directing, producing & hosting. Thought up by then-President Heiko Enderling, it's a means to learn about @smbmathbiology.bsky.social and research from its members and the wider #mathBio community.
November 26, 2024 at 8:24 PM
As a member of @smbmathbiology.bsky.social (and podcast fan) I listen to all of these, best way to keep up with the #science and the #scientists in #MathBio other than those I usually obsess about #MathOnco #MathEvo