UCSF Cell Design Institute
@cdi-ucsf.bsky.social
Official Account of the Cell Design Institute @UCSF.
Bringing a unique foundational approach to cell therapies.
https://celldesigninstitute.org
Bringing a unique foundational approach to cell therapies.
https://celldesigninstitute.org
WE ARE HIRING! CDI and Lim Lab at UCSF are looking for technicians (pre-PhD level) for a variety of cell engineering and synthetic biology projects. Past trainees have gone on to PhD/MD/careers at great places including UCSF, Harvard, Genentech, UCSD, etc!
Apply here: aprecruit.ucsf.edu/JPF05588
Apply here: aprecruit.ucsf.edu/JPF05588
Junior or Assistant Specialist
University of California, San Francisco is hiring. Apply now!
aprecruit.ucsf.edu
May 16, 2025 at 1:53 AM
WE ARE HIRING! CDI and Lim Lab at UCSF are looking for technicians (pre-PhD level) for a variety of cell engineering and synthetic biology projects. Past trainees have gone on to PhD/MD/careers at great places including UCSF, Harvard, Genentech, UCSD, etc!
Apply here: aprecruit.ucsf.edu/JPF05588
Apply here: aprecruit.ucsf.edu/JPF05588
Reposted by UCSF Cell Design Institute
I am excited to announce that in March, I will start my lab in the Department of Cancer Biology at the University of Pennsylvania Perelman School of Medicine @pennmedicine.bsky.social @penncancer.bsky.social
stevens.bio
stevens.bio
Stevens Lab
Stevens.bio
February 7, 2025 at 3:36 AM
I am excited to announce that in March, I will start my lab in the Department of Cancer Biology at the University of Pennsylvania Perelman School of Medicine @pennmedicine.bsky.social @penncancer.bsky.social
stevens.bio
stevens.bio
The latest from Lim Lab at CDI out today in Cell! "Synthetic organizer cells guide development via spatial and biochemical instructions" led by star postdocs Toshi Yamada and Coralie Trentesaux
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Synthetic organizer cells guide development via spatial and biochemical instructions
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific morphogen gradients and systematically guide in vitro development.
www.cell.com
December 19, 2024 at 9:00 PM
The latest from Lim Lab at CDI out today in Cell! "Synthetic organizer cells guide development via spatial and biochemical instructions" led by star postdocs Toshi Yamada and Coralie Trentesaux
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted by UCSF Cell Design Institute
For our inaugural @bsky.app post – 2 papers and the cover of Science @science.org!!
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej
December 13, 2024 at 3:41 PM
Reposted by UCSF Cell Design Institute
UCSF scientists have developed a “molecular GPS” system that makes it so that T cells can target and attack brain tumor cells without harming healthy tissue: https://buff.ly/41gMxu0
https://buff.ly/4fSD40p
@cdi-ucsf.bsky.social @ucsfcancer.bsky.social @science.org
#CART #immunotherapy #glioblastoma
https://buff.ly/4fSD40p
@cdi-ucsf.bsky.social @ucsfcancer.bsky.social @science.org
#CART #immunotherapy #glioblastoma
December 13, 2024 at 7:36 PM
UCSF scientists have developed a “molecular GPS” system that makes it so that T cells can target and attack brain tumor cells without harming healthy tissue: https://buff.ly/41gMxu0
https://buff.ly/4fSD40p
@cdi-ucsf.bsky.social @ucsfcancer.bsky.social @science.org
#CART #immunotherapy #glioblastoma
https://buff.ly/4fSD40p
@cdi-ucsf.bsky.social @ucsfcancer.bsky.social @science.org
#CART #immunotherapy #glioblastoma
Reposted by UCSF Cell Design Institute
Press about recent paper on UCSF main page, in which @aparentlab.bsky.social chimes in
Engineered Immune Cells May Be Able to Tame Inflammation
A new technology uses engineered T cells that act as immune “referees” to soothe overreacting immune responses. They also can mop up inflammatory molecules without lowering the entire body’s immune sh...
www.ucsf.edu
December 6, 2024 at 10:12 PM
Press about recent paper on UCSF main page, in which @aparentlab.bsky.social chimes in
Reposted by UCSF Cell Design Institute
In @science.org this week, Reddy, Lim, & colleagues engineer engineer custom #synthetic #suppressor #TCells that produce locally targeted immune suppression. Such cells could be used to protect specific tissues from #CARTCell cross-reactivity without compromising on-target, antitumor activity!
Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs
Immune homeostasis requires a balance of inflammatory and suppressive activities. To design cells potentially useful for local immune suppression, we engineered conventional CD4+ T cells with syntheti...
www.science.org
December 5, 2024 at 10:36 PM
In @science.org this week, Reddy, Lim, & colleagues engineer engineer custom #synthetic #suppressor #TCells that produce locally targeted immune suppression. Such cells could be used to protect specific tissues from #CARTCell cross-reactivity without compromising on-target, antitumor activity!
Reposted by UCSF Cell Design Institute
In @science.org this week, Simic, Watchmaker, Zamvil, Okada, and Lim engineer #TCells specific for #CNS #ECM antigens to deliver payloads selectively to the #brain!
Programming tissue-sensing T cells that deliver therapies to the brain
To engineer cells that can specifically target the central nervous system (CNS), we identified extracellular CNS-specific antigens, including components of the CNS extracellular matrix and surface mol...
www.science.org
December 5, 2024 at 10:30 PM
In @science.org this week, Simic, Watchmaker, Zamvil, Okada, and Lim engineer #TCells specific for #CNS #ECM antigens to deliver payloads selectively to the #brain!
Reposted by UCSF Cell Design Institute
Finally here: #CellSignaling by Wendell A. Lim and Bruce J. Mayer - an excellent and comprehensive resource for researchers, lecturers, and students interested in #SignalTransduction. A perfect Christmas present for self?
November 27, 2024 at 7:32 PM
Finally here: #CellSignaling by Wendell A. Lim and Bruce J. Mayer - an excellent and comprehensive resource for researchers, lecturers, and students interested in #SignalTransduction. A perfect Christmas present for self?
For our inaugural @bsky.app post – 2 papers and the cover of Science @science.org!!
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej
December 5, 2024 at 11:59 PM
For our inaugural @bsky.app post – 2 papers and the cover of Science @science.org!!
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej
Dr. Nish Reddy et al. built T cells that suppress inflammation in specific tissues bit.ly/4fX8JxN
Dr. Milos Simic, Dr. Payal Watchmaker et al. built T cells that deliver therapies to the brain bit.ly/4g0I5Ej