Chris Ashwood
cashwood.proteaglyco.com
Chris Ashwood
@cashwood.proteaglyco.com
Director of Protea Glycosciences
Accelerating glycoscience research
30 year service contract hahaha
November 11, 2025 at 7:50 AM
Safe travels!
November 11, 2025 at 3:04 AM
Yeah, the Copenhagen PRI purchase specifies only one Astral, but something expensive is definitely not being mentioned.
November 10, 2025 at 7:40 PM
I think the strategy is that you put the effort into researching your best option and by the time you get the quotes, you’ve essentially committed to that vendor.
Then asking another vendor for their equivalent MS purchase is essentially a tick-box exercise, rather than a genuine comparison.
November 10, 2025 at 8:03 AM
GSA advantage is the best for the US since it covers all of the government.

Some public institutions (like state universities) have the tenders publicly available, but they’re a nightmare to find as each institution has their own way of making it available.
November 10, 2025 at 8:01 AM
Note that in this system, the tender value can be withheld, but you can still see which vendor won the tender.
Another instrument for comparison, a timsTOF HT, was bought at 588k EUR ($679k USD).
ted.europa.eu/en/notice/-/...
660788-2025 - Result - TED - Liferay DXP
ted.europa.eu
November 10, 2025 at 1:13 AM
Curious how they'll handle it at the conference, it's in the middle of a session. Good to see things are a constant across the commonwealth, despite where we're placed on the globe.
November 8, 2025 at 12:55 PM
Moment of silence at 11 am with the bugle recording like Australia?
November 8, 2025 at 12:16 PM
Reposted by Chris Ashwood
This is due to training cut-offs, and because in human review, manuscripts are compared against the reviewers accumulated experience, which is not primarily stored in a textual format that is publicly accessible for the LLM to use. This argues against using centralised LLMs for peer review.
November 8, 2025 at 4:46 AM
It’s obvious, but it’s missing the “human” element. Specifically, calculating the amount of money and effort required to satisfy a claim. Some approaches are just impractical.
As you’ve published in our field about AI, I feel it’s going to miss the glyco nuances.
November 7, 2025 at 10:06 PM
6, 7 hours to learn and you’re set!
November 7, 2025 at 9:08 PM
I’ve tried it and I can see it becoming the implemented solution by publishers for the reviewer shortage problem.
Which is my biggest concern.
November 7, 2025 at 8:05 PM
It’s so cute and small. Pretty refreshing to see a new MS instrument isn’t taller, wider, or longer than a car.
November 6, 2025 at 7:40 PM
I think this has been almost ready since 2023, but Astral releases took precedence. It also helps sell TMT which is also vendor-specific.
San Diego is almost a home conference for San Jose, so makes sense to have the local hardware advances showcased.
November 6, 2025 at 2:32 PM
Can confirm, he's a fixer!
November 6, 2025 at 1:28 PM