Cameron A. Schmidt PhD (He/Him) 🇺🇲
@cas-reprolab.bsky.social
Complex Adaptive Systems Lab at ECU Biology | Studying the Multiscale Biology of Searching and Finding | https://www.cas-lab.com | https://github.com/CAS-ReproLab
Pinned
Human Sperm Differential Interference Contrast (DIC)
YouTube video by ECU CAS LAB
youtu.be
To fertilize, sperm must locate and recognize an egg. How? The structure of each sperm cell encodes a latent representation of this task. We use fertilization as a simple model process to study the nature of latent encoding. #ComplexSystems #ReproRocks
youtu.be/c1aoQ4aILIw?...
youtu.be/c1aoQ4aILIw?...
Corey Maley's 'How and Why to think that the brain is literally a computer'. Analog representation is hands down the most empirically tractable model to explain and predict how biological systems solve problems through their structure and dynamics.
www.frontiersin.org/journals/com...
www.frontiersin.org/journals/com...
Frontiers | How (and why) to think that the brain is literally a computer
The relationship between brains and computers is often taken to be merely metaphorical. However, genuine computation can be implemented in virtually any medi...
www.frontiersin.org
October 8, 2025 at 9:56 AM
Corey Maley's 'How and Why to think that the brain is literally a computer'. Analog representation is hands down the most empirically tractable model to explain and predict how biological systems solve problems through their structure and dynamics.
www.frontiersin.org/journals/com...
www.frontiersin.org/journals/com...
How long (on average) would fertilization take if only one sperm were inseminated at a time? About 1,902 years! No wonder evolution parallelized this process! Used a geometric distribution to estimate with 2 hrs per fertilization attempt and success probability of 12/10^8. #Maths #ReproRocks
October 5, 2025 at 1:48 PM
How long (on average) would fertilization take if only one sperm were inseminated at a time? About 1,902 years! No wonder evolution parallelized this process! Used a geometric distribution to estimate with 2 hrs per fertilization attempt and success probability of 12/10^8. #Maths #ReproRocks
Cool paper modeling local self organization by enzymes depending on local substrate concentration. Macromolecules only do one thing... Stick to stuff. The range of behaviors that simple property produces is astounding. #ComplexSystems #Biochemistry journals.aps.org/prxlife/abst...
Sticky Enzymes: Increased Metabolic Efficiency via Substrate-Dependent Enzyme Clustering
Enzyme clustering boosts metabolic pathway flux and lowers toxic intermediates by self-assembling only where and when substrate is present, enabling an efficient and adaptive pathway processing.
journals.aps.org
August 15, 2025 at 9:46 AM
Cool paper modeling local self organization by enzymes depending on local substrate concentration. Macromolecules only do one thing... Stick to stuff. The range of behaviors that simple property produces is astounding. #ComplexSystems #Biochemistry journals.aps.org/prxlife/abst...
#Repro friends, I'm hosting a series of podcasts for
@ssrepro.bsky.social ! In this series we'll explore how scientists from different fields approach the study of sperm, eggs, and embryos! First episode with Dr. Pablo Visconti! Link below or wherever you get your🎙️
ssr.org/ssr-resource...
@ssrepro.bsky.social ! In this series we'll explore how scientists from different fields approach the study of sperm, eggs, and embryos! First episode with Dr. Pablo Visconti! Link below or wherever you get your🎙️
ssr.org/ssr-resource...
a cartoon of homer simpson in a circle
ALT: a cartoon of homer simpson in a circle
media.tenor.com
August 14, 2025 at 10:26 AM
#Repro friends, I'm hosting a series of podcasts for
@ssrepro.bsky.social ! In this series we'll explore how scientists from different fields approach the study of sperm, eggs, and embryos! First episode with Dr. Pablo Visconti! Link below or wherever you get your🎙️
ssr.org/ssr-resource...
@ssrepro.bsky.social ! In this series we'll explore how scientists from different fields approach the study of sperm, eggs, and embryos! First episode with Dr. Pablo Visconti! Link below or wherever you get your🎙️
ssr.org/ssr-resource...
What a biological system does at any given moment is encoded by evolution, but entrained by circumstance. All of our experiments necessarily shape the behaviors we observe. This lack of useful reference point is what makes experimental biology difficult. #ComplexSystems
August 14, 2025 at 9:59 AM
What a biological system does at any given moment is encoded by evolution, but entrained by circumstance. All of our experiments necessarily shape the behaviors we observe. This lack of useful reference point is what makes experimental biology difficult. #ComplexSystems
Just listened to an incredibly interesting conversation on the Jim Rutt show about representation and some potentially relevant concepts for the future of machine intelligence scaling. The biological implications really resonated with me🤔 #ComplexSystems
www.jimruttshow.com/ken-stanley-3/
www.jimruttshow.com/ken-stanley-3/
EP 316 Ken Stanley on the AI Representation Problem - The Jim Rutt Show
Jim talks with Ken Stanley about the Fractured Entanglement Representation hypothesis in deep learning neural networks. They discuss open-endedness in AI systems & evolution, the Picbreeder experiment...
www.jimruttshow.com
August 10, 2025 at 10:00 PM
Just listened to an incredibly interesting conversation on the Jim Rutt show about representation and some potentially relevant concepts for the future of machine intelligence scaling. The biological implications really resonated with me🤔 #ComplexSystems
www.jimruttshow.com/ken-stanley-3/
www.jimruttshow.com/ken-stanley-3/
William Bialek on emergence of macroscopic behaviors as an evolving theme in physics👏🔥 #ComplexSystems
journals.aps.org/prxlife/abst...
journals.aps.org/prxlife/abst...
Emergence of Brains
This review traces how ideas from statistical physics evolved into foundational models of neural computation, shaping modern AI and culminating in the 2024 Nobel Prize in Physics.
journals.aps.org
August 9, 2025 at 10:50 AM
William Bialek on emergence of macroscopic behaviors as an evolving theme in physics👏🔥 #ComplexSystems
journals.aps.org/prxlife/abst...
journals.aps.org/prxlife/abst...
Reposted by Cameron A. Schmidt PhD (He/Him) 🇺🇲
We're looking for a Postdoctoral Fellow in Machine Learning & Women’s Health in partnership with MIT’s Female Medicine through Machine Learning (FMML fmml.mit.edu ) to build multi-modal ML models related to ovarian aging and its impact on overall health using large, real-world datasets.
Postdoc Research Fellow Pepin Lab
Site: Massachusetts General Physicians Organization, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and syste...
massgeneralbrigham.wd1.myworkdayjobs.com
August 8, 2025 at 3:49 PM
We're looking for a Postdoctoral Fellow in Machine Learning & Women’s Health in partnership with MIT’s Female Medicine through Machine Learning (FMML fmml.mit.edu ) to build multi-modal ML models related to ovarian aging and its impact on overall health using large, real-world datasets.
Not as pretty, but now completely sourced from Amazon or Walmart, except for the syringe pump... Just a few cents per device. Leak testing with mineral oil, so I'm very pleased this didn't devolve into a mess😋
August 7, 2025 at 1:24 PM
Not as pretty, but now completely sourced from Amazon or Walmart, except for the syringe pump... Just a few cents per device. Leak testing with mineral oil, so I'm very pleased this didn't devolve into a mess😋
Making a microfluidic device for isolation of sub-microliter droplets to trap sperm for long-term motility imaging in a single field. This is the science version of posting pictures of food😋 #BestJobEver #ReproRocks
August 6, 2025 at 11:37 PM
Making a microfluidic device for isolation of sub-microliter droplets to trap sperm for long-term motility imaging in a single field. This is the science version of posting pictures of food😋 #BestJobEver #ReproRocks
Interesting take from James Holehouse @sfiscience.bsky.social on how deterministic definitions of behavioral modes may be misleading in biological systems with significant noise. #ComplexSystems #Biochemistry
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
August 5, 2025 at 10:21 AM
Interesting take from James Holehouse @sfiscience.bsky.social on how deterministic definitions of behavioral modes may be misleading in biological systems with significant noise. #ComplexSystems #Biochemistry
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
From Shosei Yoshida's beautiful talk @ssrepro.bsky.social. Differentiation waves in mouse seminiferous tubules (Stra-8 eGFP). Absolutely spectacular👏 #ReproRocks #ComplexSystems #Microscopy
August 4, 2025 at 10:09 AM
From Shosei Yoshida's beautiful talk @ssrepro.bsky.social. Differentiation waves in mouse seminiferous tubules (Stra-8 eGFP). Absolutely spectacular👏 #ReproRocks #ComplexSystems #Microscopy
December 11, 2024 at 4:24 PM
Looks super interesting🔥 Model that characterizes bidirectional causation in scale entwined systems by iteratively combining microstate dynamics with macrostate information entropy🤔 #ComplexSystems
www.pnas.org/doi/epub/10....
www.pnas.org/doi/epub/10....
Dynamical theory of complex systems with two-way micro–macro causation
www.pnas.org
December 9, 2024 at 11:19 AM
Looks super interesting🔥 Model that characterizes bidirectional causation in scale entwined systems by iteratively combining microstate dynamics with macrostate information entropy🤔 #ComplexSystems
www.pnas.org/doi/epub/10....
www.pnas.org/doi/epub/10....
15 cumulative years of time lapse videos of different plants growing from seeds. Very cool👏 Highlights the importance of state space exploration in organismal biology. #ComlexSystems
youtube.com/watch?v=NtsJ...
youtube.com/watch?v=NtsJ...
youtube.com
December 8, 2024 at 2:52 PM
15 cumulative years of time lapse videos of different plants growing from seeds. Very cool👏 Highlights the importance of state space exploration in organismal biology. #ComlexSystems
youtube.com/watch?v=NtsJ...
youtube.com/watch?v=NtsJ...
Haven't worked through this yet, but it looks amazing👏🔥 ##MDSim #Biochemistry
mdcourse.github.io/index.html
mdcourse.github.io/index.html
ContentsMenuExpandLight modeDark modeAuto light/dark, in light modeAuto light/dark, in dark mode
mdcourse.github.io
December 5, 2024 at 12:18 AM
Haven't worked through this yet, but it looks amazing👏🔥 ##MDSim #Biochemistry
mdcourse.github.io/index.html
mdcourse.github.io/index.html
Made this #DataScience crash course notebook as a homework assignment for my graduate #Biochemistry course. From variables to data frames and plotting in just a few easy steps💻 Uses some tabular data from Pubchem #Python
github.com/CAS-ReproLab...
github.com/CAS-ReproLab...
BIOL_6240/Homework/HW5_Intro_DataSci.ipynb at main · CAS-ReproLab/BIOL_6240
This Repository Supports BIOL 6240 - Graduate Biochemistry (East Carolina University) - CAS-ReproLab/BIOL_6240
github.com
December 4, 2024 at 11:56 PM
Made this #DataScience crash course notebook as a homework assignment for my graduate #Biochemistry course. From variables to data frames and plotting in just a few easy steps💻 Uses some tabular data from Pubchem #Python
github.com/CAS-ReproLab...
github.com/CAS-ReproLab...
To fertilize, sperm must locate and recognize an egg. How? The structure of each sperm cell encodes a latent representation of this task. We use fertilization as a simple model process to study the nature of latent encoding. #ComplexSystems #ReproRocks
youtu.be/c1aoQ4aILIw?...
youtu.be/c1aoQ4aILIw?...
Human Sperm Differential Interference Contrast (DIC)
YouTube video by ECU CAS LAB
youtu.be
December 4, 2024 at 11:09 AM
To fertilize, sperm must locate and recognize an egg. How? The structure of each sperm cell encodes a latent representation of this task. We use fertilization as a simple model process to study the nature of latent encoding. #ComplexSystems #ReproRocks
youtu.be/c1aoQ4aILIw?...
youtu.be/c1aoQ4aILIw?...
Jupyter notebook with four examples of animated plotting using Matplotlib FuncAnimation. Includes- a sine wave, 1D random walk, Conway's game of life, and a damped harmonic oscillator. Great skill for your seminar presentations😎 #PythonUtils #FunWithModels
December 4, 2024 at 10:33 AM
Jupyter notebook with four examples of animated plotting using Matplotlib FuncAnimation. Includes- a sine wave, 1D random walk, Conway's game of life, and a damped harmonic oscillator. Great skill for your seminar presentations😎 #PythonUtils #FunWithModels