Caghan Kizil
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cakizil.bsky.social
Caghan Kizil
@cakizil.bsky.social
Scientist, father, pet lover.
Associate Professor, Columbia University Irving Medical Center, New York.
Zebrafish | Alzheimer’s disease | Functional genomics | Neuroscience

• www.kizillab.org
https://www.neurology.columbia.edu/profile/caghan-kizil-phd
His legacy is irrevocably tainted by misogynist and racist statements. We should remember both the science and the harm. I, for one, will remember Rosalind Franklin more.

www.nytimes.com/2025/11/07/s...
James D. Watson, Co-Discoverer of the Structure of DNA, Is Dead at 97
www.nytimes.com
November 8, 2025 at 5:35 AM
Reposted by Caghan Kizil
Don't miss the amazing line-up of talks in the 'Ageing and Adult Disease Models' session at #ZDM18. Featuring Caghan Kizil
@cakizil.bsky.social who will be speaking about 'Blood-Brain Barrier Pathophysiology and Therapeutic Opportunities in Alzheimer’s Disease' #zdmsECI #ZDMSociety
October 11, 2025 at 1:17 AM
▶️ #Preprint @medrxivpreprint.bsky.social on our novel multiome resource from 52 #human brains of Hispanic ancestry, known to bear high vascular pathology. In @elanuryilmaz.bsky.social et al., we analyzed the effects of #APOE-ε4, a strong genetic risk factor for #Alzheimer's.

doi.org/10.1101/2025...
Single-nucleus multiomics in brains from Hispanic individuals reveal APOE-ε4-driven disruption of focal adhesion signaling in the presence of cerebrovascular pathology
The apolipoprotein E4 allele (APOEϵ4) is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), yet its molecular impact on cerebrovascular biology remains inconclusive, particular...
doi.org
May 22, 2025 at 3:48 PM
#2024Recap
2024 was an amazing year for #KizilLab with impactful publications, awards, patent applications, and discoveries with #zebrafish. These wouldn't be possible without our excellent team, collaborators, supporters &
@columbiauniversity.bsky.social. Big thanks! 💙 Looking fwd to more in 2025!🌟
December 31, 2024 at 3:24 AM
Wherever you are and whichever of the diverse celebrations you observe today, 🎄 Merry #Christmas , 🕎 Happy #Hanukkah, 🕯️ Happy #Kwanzaa, 🌞 Blessed #Yule and any other holiday you celebrate this season.This must remind us of the shared values of humanity and unity in diversity. #HappyHolidays
December 25, 2024 at 10:43 PM
Reposted by Caghan Kizil
Using X/Twitter data from nine countries, a study in Nature Communications shows that out-group mentions use more toxic language than in-group mentions, and political mentions are more toxic than apolitical mentions. https://go.nature.com/417N7KG 🧪
November 29, 2024 at 4:09 PM
Reposted by Caghan Kizil
🚨 Our new study out in @natureportfolio.bsky.social! 🌟
We identify the "little brain" of the heart: the intricate intracardiac nervous system (IcNS) of zebrafish! 🐟

More about how this changes what we know about heart functionality.
#Zebrafish #Neuroscience #LittleBrain

doi.org/10.1038/s414...
Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system - Nature Communications
Although the heart has its own nervous system, its organization and functionality remain largely unknown. Here, the authors reveal the molecular, chemical, and functional diversity of neurons within t...
doi.org
December 4, 2024 at 3:15 PM
🚨 Our new study out in @natureportfolio.bsky.social! 🌟
We identify the "little brain" of the heart: the intricate intracardiac nervous system (IcNS) of zebrafish! 🐟

More about how this changes what we know about heart functionality.
#Zebrafish #Neuroscience #LittleBrain

doi.org/10.1038/s414...
Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system - Nature Communications
Although the heart has its own nervous system, its organization and functionality remain largely unknown. Here, the authors reveal the molecular, chemical, and functional diversity of neurons within t...
doi.org
December 4, 2024 at 3:15 PM
Saturday evening #cat
November 30, 2024 at 11:32 PM
Our review on multi-target drugs and their use in Alzheimer's disease in Trends in Pharmacological Sciences @cellpress.bsky.social

doi.org/10.1016/j.ti...
November 29, 2024 at 9:52 PM
www.cuimc.columbia.edu/news/study-s...

#NewPublication
Changes in ABCA7 gene links to a greater risk of Alzheimer’s, but it was unclear how the variants advance the disease. We have discovered how variants of the ABCA7 gene, which are common among Black Americans, increase the risk for Alzheimer’s.
Study Shows How Common Genetic Variants in Black Americans Increase Alzheimer’s Risk
Variants of the ABCA7 gene accelerate neurodegeneration by reducing the amount of neuropeptide Y, a protein essential for maintaining brain synapses.
www.cuimc.columbia.edu
November 21, 2024 at 2:18 AM