Lindsey Goodman
brainyfly.bsky.social
Lindsey Goodman
@brainyfly.bsky.social
Neuroscience PhD; postdoc in the Bellen lab at BCM; neurogenetics; Drosophila; neurodegenerative diseases: AD, PiD, FTD, PSP, CBD, ALS; neuron glia communication; lipid droplets
As a senior postdoc looking at professor positions I now have no idea how to move forward. The major discovery we made in the Bellen lab that Tau plays a protective role in glia needs further study to understand neurodegenerative diseases. I can't move forward without NIH standing.
All federal grants and loan disbursement paused by White House | CNN Politics
The White House budget office has ordered a pause on all federal grants and loans, according to an internal memorandum sent Monday.
www.cnn.com
January 28, 2025 at 12:01 PM
Reposted by Lindsey Goodman
GWAS provides a unique tool in human biology as it can establish causal links from variants to trait.

But interpretation is difficult as most effects flow through (unobserved) gene regulatory networks. Can we gain insight by linking to modern Perturb-seq data?

www.biorxiv.org/content/10.1...
Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seq
Genetic association studies provide a unique tool for identifying causal links from genes to human traits and diseases. However, it is challenging to determine the biological mechanisms underlying mos...
www.biorxiv.org
January 26, 2025 at 12:13 AM