Laura Bradfield (she/her)
@bradfield-neuro.bsky.social
Behavioural neuroscientist. With a 'u'. Slight obsession with astrocytes
Pinned
Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
Neuropsychopharmacology - Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
rdcu.be
rdcu.be/eIyQB
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Got an invitation to provide an article for a journal called "Nature, Cell, and Science" and was wondering if it was predatory. Google gave me this reddit thread, funny:
www.reddit.com/r/labrats/co...
www.reddit.com/r/labrats/co...
From the labrats community on Reddit: Predatory journal: let’s sound impactful by having a combined name of Nature, Cell, and Science 😂😂
Explore this post and more from the labrats community
www.reddit.com
October 21, 2025 at 11:11 PM
Got an invitation to provide an article for a journal called "Nature, Cell, and Science" and was wondering if it was predatory. Google gave me this reddit thread, funny:
www.reddit.com/r/labrats/co...
www.reddit.com/r/labrats/co...
Reposted by Laura Bradfield (she/her)
First alcohol lab paper out today! Neurotoxic effects of chronic ethanol on cholinergic interneurons in the dorsomedial striatum.
doi.org/10.1016/j.ne...
Many thanks to all contributors!
doi.org/10.1016/j.ne...
Many thanks to all contributors!
Redirecting
doi.org
October 13, 2025 at 4:23 PM
First alcohol lab paper out today! Neurotoxic effects of chronic ethanol on cholinergic interneurons in the dorsomedial striatum.
doi.org/10.1016/j.ne...
Many thanks to all contributors!
doi.org/10.1016/j.ne...
Many thanks to all contributors!
rdcu.be/eIyQB
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
Neuropsychopharmacology - Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
rdcu.be
September 29, 2025 at 12:38 AM
rdcu.be/eIyQB
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Now published in Neuropsychopharmacology, here we mimicked the striatal neuroinflammation seen in the brains of individuals with compulsive disorders and found that this facilitated goal-directed action, whereas activating the Gi pathway in astrocytes prevented it
Reposted by Laura Bradfield (she/her)
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling
Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear. Here, we probed the di...
www.biorxiv.org
September 25, 2025 at 10:12 PM
Latest lab preprint! Astrocytes are a brain cell type vulnerable to the effects of stress and the development of psychiatric-like phenotypes in animals, yet how this translates to humans is unclear... so we dived in:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Laura Bradfield (she/her)
Reposted by Laura Bradfield (she/her)
Position open for a neuroimaging focused postdoc to come work with us in Sydney
Feel free to get in touch for a chat if you have any questions about it :)
usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
Feel free to get in touch for a chat if you have any questions about it :)
usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
August 15, 2025 at 1:18 AM
Position open for a neuroimaging focused postdoc to come work with us in Sydney
Feel free to get in touch for a chat if you have any questions about it :)
usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
Feel free to get in touch for a chat if you have any questions about it :)
usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
New preprint from the lab, produced in collaboration with Simon Killcross' lab:
Modelling compulsive actions in rats and mice: The back-translation of value-modulated attentional capture from humans to rodents
doi.org/10.31234/osf...
I will be presenting some of this work at Pavlovian next week!
Modelling compulsive actions in rats and mice: The back-translation of value-modulated attentional capture from humans to rodents
doi.org/10.31234/osf...
I will be presenting some of this work at Pavlovian next week!
OSF
doi.org
July 30, 2025 at 4:35 AM
New preprint from the lab, produced in collaboration with Simon Killcross' lab:
Modelling compulsive actions in rats and mice: The back-translation of value-modulated attentional capture from humans to rodents
doi.org/10.31234/osf...
I will be presenting some of this work at Pavlovian next week!
Modelling compulsive actions in rats and mice: The back-translation of value-modulated attentional capture from humans to rodents
doi.org/10.31234/osf...
I will be presenting some of this work at Pavlovian next week!
Reposted by Laura Bradfield (she/her)
Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
July 22, 2025 at 8:54 PM
Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Laura Bradfield (she/her)
New paper out! Here we show that attentional biases induced by reward history depend on awareness of such reward history (w/ @jlupiane.bsky.social and @mavadillo.bsky.social).
link.springer.com/article/10.3...
👇🧵
link.springer.com/article/10.3...
👇🧵
Value-modulated attentional capture depends on awareness - Psychonomic Bulletin & Review
Value-modulated attentional capture (VMAC) refers to a process by which a priori neutral stimuli gain attentional priority when associated with reward, independently of goal or stimulus-driven attenti...
link.springer.com
July 21, 2025 at 5:08 AM
New paper out! Here we show that attentional biases induced by reward history depend on awareness of such reward history (w/ @jlupiane.bsky.social and @mavadillo.bsky.social).
link.springer.com/article/10.3...
👇🧵
link.springer.com/article/10.3...
👇🧵
I would add to this that journals are increasingly asking more of reviewers (e.g. format reviews in a specific way, long consults on top of reviewing) which I understand the reasoning for, but it does increase burden, and increase difficulty to find reviewers.
www.theguardian.com/science/2025...
www.theguardian.com/science/2025...
Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
www.theguardian.com
July 14, 2025 at 4:55 AM
I would add to this that journals are increasingly asking more of reviewers (e.g. format reviews in a specific way, long consults on top of reviewing) which I understand the reasoning for, but it does increase burden, and increase difficulty to find reviewers.
www.theguardian.com/science/2025...
www.theguardian.com/science/2025...
Reposted by Laura Bradfield (she/her)
doing Concur reports
June 17, 2025 at 10:49 PM
doing Concur reports
Couldn't be more proud of these two who graduated today, Drs Abiero and Ganesan.
May 6, 2025 at 4:39 AM
Couldn't be more proud of these two who graduated today, Drs Abiero and Ganesan.
Reposted by Laura Bradfield (she/her)
💥GIF THREAD ALERT – pleased to share our latest paper @sfnjournals.bsky.social in J Neurosci- an epic over 5 years in the making examining amygdala and prefrontal interactions with the medial OFC in risk/reward decisions by Nicole Jenni and Deb Bercovici
www.jneurosci.org/content/45/1...
www.jneurosci.org/content/45/1...
Medial Orbitofrontal, Prefrontal, and Amygdalar Circuits Support Dissociable Component Processes of Risk/Reward Decision-Making
The medial orbitofrontal cortex (mOFC) has been implicated in shaping decisions involving reward uncertainty, in part by using memories to infer future outcomes. This region is interconnected with oth...
www.jneurosci.org
April 23, 2025 at 1:12 AM
💥GIF THREAD ALERT – pleased to share our latest paper @sfnjournals.bsky.social in J Neurosci- an epic over 5 years in the making examining amygdala and prefrontal interactions with the medial OFC in risk/reward decisions by Nicole Jenni and Deb Bercovici
www.jneurosci.org/content/45/1...
www.jneurosci.org/content/45/1...
It's gonna be epic!
🚨LAST DAY to submit poster abstracts for the PAVLOVIAN 2025 annual meeting 🚨
Check out our 🔥 program and submit abstracts in the link below, with 5 travel awards available for students and postdocs! 🧠
Check out our 🔥 program and submit abstracts in the link below, with 5 travel awards available for students and postdocs! 🧠
April 10, 2025 at 11:42 PM
It's gonna be epic!
Reposted by Laura Bradfield (she/her)
Don’t forget to submit your data blitz or poster abstracts for PAVLOVIAN in SYDNEY!🧪🧠
Due April 11th, including 5 x travel awards to help our buddies from the 🇺🇸 and elsewhere get to 🇦🇺
Our line up is 🔥 Check out our website, registration, and hotel block below 👇
Due April 11th, including 5 x travel awards to help our buddies from the 🇺🇸 and elsewhere get to 🇦🇺
Our line up is 🔥 Check out our website, registration, and hotel block below 👇
March 20, 2025 at 7:43 PM
Don’t forget to submit your data blitz or poster abstracts for PAVLOVIAN in SYDNEY!🧪🧠
Due April 11th, including 5 x travel awards to help our buddies from the 🇺🇸 and elsewhere get to 🇦🇺
Our line up is 🔥 Check out our website, registration, and hotel block below 👇
Due April 11th, including 5 x travel awards to help our buddies from the 🇺🇸 and elsewhere get to 🇦🇺
Our line up is 🔥 Check out our website, registration, and hotel block below 👇
Reposted by Laura Bradfield (she/her)
Exciting new science from the lab led by @melcooperphd.bsky.social.
More to come soon!
More to come soon!
Fresh off the press! We found that degeneration in one retina causes astrocytes to respond retinotopically across *both* hemispheres of the brain. Perhaps astrocytes across the CNS are able to coordinate their responses more than we anticipated... www.pnas.org/doi/10.1073/...
March 10, 2025 at 10:58 PM
Exciting new science from the lab led by @melcooperphd.bsky.social.
More to come soon!
More to come soon!
For those hurting after DP EOI outcomes today, courtesy of ChatGPT (I prompted with the first line, it will have to go over 2 posts as it's too long):
Oh ARC, why won't you fund me?
I’ve written papers, set them free,
With research deep and insights bright,
Yet still, no grant, no guiding light.
Oh ARC, why won't you fund me?
I’ve written papers, set them free,
With research deep and insights bright,
Yet still, no grant, no guiding light.
February 28, 2025 at 3:13 AM
For those hurting after DP EOI outcomes today, courtesy of ChatGPT (I prompted with the first line, it will have to go over 2 posts as it's too long):
Oh ARC, why won't you fund me?
I’ve written papers, set them free,
With research deep and insights bright,
Yet still, no grant, no guiding light.
Oh ARC, why won't you fund me?
I’ve written papers, set them free,
With research deep and insights bright,
Yet still, no grant, no guiding light.
Reposted by Laura Bradfield (she/her)
The ARC have tweeted that they will released Discovery Projects Expression of Interest outcomes tomorrow.
February 27, 2025 at 12:25 AM
The ARC have tweeted that they will released Discovery Projects Expression of Interest outcomes tomorrow.
Jon Stewart's take on DOGE, in case you feel like laughing and crying at the same time 🫤:
www.youtube.com/watch?v=utl2...
www.youtube.com/watch?v=utl2...
www.youtube.com
February 25, 2025 at 11:10 PM
Jon Stewart's take on DOGE, in case you feel like laughing and crying at the same time 🫤:
www.youtube.com/watch?v=utl2...
www.youtube.com/watch?v=utl2...
Reposted by Laura Bradfield (she/her)
Diversity is our greatest asset, even if the government disagrees… They not like us! POC in STEM are here to stay.
They tried to rig the game but you can’t fake influence!
Mustard on the [Be][At] bro.
Happy Black History Month!
They tried to rig the game but you can’t fake influence!
Mustard on the [Be][At] bro.
Happy Black History Month!
February 21, 2025 at 12:20 AM
Diversity is our greatest asset, even if the government disagrees… They not like us! POC in STEM are here to stay.
They tried to rig the game but you can’t fake influence!
Mustard on the [Be][At] bro.
Happy Black History Month!
They tried to rig the game but you can’t fake influence!
Mustard on the [Be][At] bro.
Happy Black History Month!
Reposted by Laura Bradfield (she/her)
🚨📃New Wassum Lab Paper📃🚨
Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇
www.nature.com/articles/s41...
Free full text: rdcu.be/eaxEv
Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇
www.nature.com/articles/s41...
Free full text: rdcu.be/eaxEv
A dual-pathway architecture for stress to disrupt agency and promote habit - Nature
Adaptive decision-making often requires an understanding of our agency in a situation; however, chronic stress can disrupt agency and promote inflexible, habitual behaviour by turning off a brain path...
www.nature.com
February 19, 2025 at 11:37 PM
🚨📃New Wassum Lab Paper📃🚨
Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇
www.nature.com/articles/s41...
Free full text: rdcu.be/eaxEv
Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇
www.nature.com/articles/s41...
Free full text: rdcu.be/eaxEv
I know everything is falling apart so this may not be the best time to post this, but know that we are watching on in horror in Australia and will do what we can to help.
Anyway, Psy post wrote an article about our article: www.psypost.org/brain-inflam...
www.sciencedirect.com/science/arti...
Anyway, Psy post wrote an article about our article: www.psypost.org/brain-inflam...
www.sciencedirect.com/science/arti...
Brain inflammation affects behavior differently in males and females, study finds
Inflammation in the hippocampus alters motivated behavior in mice, but in opposite ways for males and females regarding food seeking and memory.
www.psypost.org
February 18, 2025 at 1:30 AM
I know everything is falling apart so this may not be the best time to post this, but know that we are watching on in horror in Australia and will do what we can to help.
Anyway, Psy post wrote an article about our article: www.psypost.org/brain-inflam...
www.sciencedirect.com/science/arti...
Anyway, Psy post wrote an article about our article: www.psypost.org/brain-inflam...
www.sciencedirect.com/science/arti...
Reposted by Laura Bradfield (she/her)
Happy to share the latest finding on anterior cingulate cortex (ACC) and information choices from @vgonzalez.bsky.social ! #neuroscience
1/n
www.eneuro.org/content/earl...
1/n
www.eneuro.org/content/earl...
A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices
Humans and non-humans alike often make choices to gain information, even when the information cannot be used to change the outcome. Prior research has shown the anterior cingulate cortex (ACC) is impo...
www.eneuro.org
February 13, 2025 at 10:29 PM
Happy to share the latest finding on anterior cingulate cortex (ACC) and information choices from @vgonzalez.bsky.social ! #neuroscience
1/n
www.eneuro.org/content/earl...
1/n
www.eneuro.org/content/earl...
Enjoyed the use of the word "bollocks"in the first paragraph 😆
Preparing research articles: An appeal to author-ity. #Matter
Open Access
www.cell.com/matter/fullt...
Open Access
www.cell.com/matter/fullt...
February 13, 2025 at 12:41 AM
Enjoyed the use of the word "bollocks"in the first paragraph 😆