Boël Lab
@boellab.bsky.social
We are a research lab located in Paris, France.
We work on the fundamental aspect of protein synthesis mechanisms and regulations.
We work on the fundamental aspect of protein synthesis mechanisms and regulations.
Pinned
Boël Lab
@boellab.bsky.social
· Mar 3
Redirecting
doi.org
I am very happy to present our new manuscript in collaboration with the Aalbet and Hunt Labs on DNA sequence optimization for high expression in Escherichia coli as well as in in vitro translation assays (doi.org/10.1016/j.jm...)
Reposted by Boël Lab
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.
www.science.org
September 6, 2025 at 9:35 AM
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
A useful toolkit 🧰⚙️
Happy to share our genetic toolkit designed to make your gene editing (life) easier, faster and very efficient!
Also suitable to build saturated chromosomal variant libraries using oligo-recombineering with extra short homology arms!
www.biorxiv.org/content/10.1...
Also suitable to build saturated chromosomal variant libraries using oligo-recombineering with extra short homology arms!
www.biorxiv.org/content/10.1...
March 24, 2025 at 5:25 PM
A useful toolkit 🧰⚙️
Thanks for the great meeting.
It was so nice to see everyone and enjoy great science. 🔤❤️
It was so nice to see everyone and enjoy great science. 🔤❤️
We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025
See you next time!🗻⛷️🚠🧬🧫🧪💙
See you next time!🗻⛷️🚠🧬🧫🧪💙
March 7, 2025 at 9:23 AM
Thanks for the great meeting.
It was so nice to see everyone and enjoy great science. 🔤❤️
It was so nice to see everyone and enjoy great science. 🔤❤️
Reposted by Boël Lab
In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 1, 2025 at 1:40 PM
In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
I am very happy to present our new manuscript in collaboration with the Aalbet and Hunt Labs on DNA sequence optimization for high expression in Escherichia coli as well as in in vitro translation assays (doi.org/10.1016/j.jm...)
Redirecting
doi.org
March 3, 2025 at 11:40 AM
I am very happy to present our new manuscript in collaboration with the Aalbet and Hunt Labs on DNA sequence optimization for high expression in Escherichia coli as well as in in vitro translation assays (doi.org/10.1016/j.jm...)
Super happy to be with the ABC family
It's ABC protein, NOT transporter! We are an inclusive bunch! ❤️
Gregory Boel introducing the morning speakers! #ABC2025
Gregory Boel introducing the morning speakers! #ABC2025
March 1, 2025 at 8:23 PM
Super happy to be with the ABC family
Reposted by Boël Lab
Direct RNA sequencing coupled with adaptive sampling enriches RNAs of interest in the transcriptome www.nature.com/articles/s41... #jcampubs
Direct RNA sequencing coupled with adaptive sampling enriches RNAs of interest in the transcriptome ...
It can be difficult to find rare transcripts when sequencing a transcriptome. Here the authors show adaptive sampling on direct RNA runs to increase the likelihood of finding less frequent ones while ...
www.nature.com
January 12, 2024 at 2:29 PM
Direct RNA sequencing coupled with adaptive sampling enriches RNAs of interest in the transcriptome www.nature.com/articles/s41... #jcampubs
Reposted by Boël Lab
check it out!
RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution
🔎 microprotein
🧬 + 🖥️
www.biorxiv.org/content/10.1...
RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution
🔎 microprotein
🧬 + 🖥️
www.biorxiv.org/content/10.1...
RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
January 13, 2024 at 2:31 AM
check it out!
RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution
🔎 microprotein
🧬 + 🖥️
www.biorxiv.org/content/10.1...
RiboGraph: An interactive visualization system for ribosome profiling data at read length resolution
🔎 microprotein
🧬 + 🖥️
www.biorxiv.org/content/10.1...
Reposted by Boël Lab
www.biorxiv.org/content/10.1...
Time resolution in cryo-EM using a novel PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Just accepted by CELL as a resource article.
Time resolution in cryo-EM using a novel PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Just accepted by CELL as a resource article.
November 25, 2023 at 8:58 PM
www.biorxiv.org/content/10.1...
Time resolution in cryo-EM using a novel PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Just accepted by CELL as a resource article.
Time resolution in cryo-EM using a novel PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Just accepted by CELL as a resource article.
Hi everyone,
We are new on Bluesky 😀. We are a group of microbiologists 🧫🔬 interested in mRNA translation mechanisms and regulation.
We wish you a wonderful year in 2024 🥳🍾 and will be back soon with more news.
We are new on Bluesky 😀. We are a group of microbiologists 🧫🔬 interested in mRNA translation mechanisms and regulation.
We wish you a wonderful year in 2024 🥳🍾 and will be back soon with more news.
January 3, 2024 at 12:30 PM
Hi everyone,
We are new on Bluesky 😀. We are a group of microbiologists 🧫🔬 interested in mRNA translation mechanisms and regulation.
We wish you a wonderful year in 2024 🥳🍾 and will be back soon with more news.
We are new on Bluesky 😀. We are a group of microbiologists 🧫🔬 interested in mRNA translation mechanisms and regulation.
We wish you a wonderful year in 2024 🥳🍾 and will be back soon with more news.
Reposted by Boël Lab
Global regulation via modulation of ribosome pausing by EttA https://www.biorxiv.org/content/10.1101/2023.10.17.562674v1
Global regulation via modulation of ribosome pausing by EttA https://www.biorxiv.org/content/10.1101/2023.10.17.562674v1
Having multiple rounds of translation of the same mRNA is a key feature of the Central Dogma that cr
www.biorxiv.org
October 18, 2023 at 3:27 AM
Global regulation via modulation of ribosome pausing by EttA https://www.biorxiv.org/content/10.1101/2023.10.17.562674v1