Boël Lab
@boellab.bsky.social
We are a research lab located in Paris, France.
We work on the fundamental aspect of protein synthesis mechanisms and regulations.
We work on the fundamental aspect of protein synthesis mechanisms and regulations.
Congratulations great story
September 5, 2025 at 9:34 AM
Congratulations great story
Reposted by Boël Lab
In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 1, 2025 at 1:40 PM
In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The second method does the same but also
optimizes all other codons using the 44 best codons identified in our
previously published efficiency codon metric (doi.org/10.1038/natu...). The last method (AG29G) follows a similar
approach but utilizes only the 29 best codons.
optimizes all other codons using the 44 best codons identified in our
previously published efficiency codon metric (doi.org/10.1038/natu...). The last method (AG29G) follows a similar
approach but utilizes only the 29 best codons.
Codon influence on protein expression in E. coli correlates with mRNA levels - Nature
In-depth analyses of protein expression studies are used to derive a new codon-influence metric that correlates with global protein levels, mRNA levels and mRNA lifetimes in vivo, indicating tight cou...
doi.org
March 3, 2025 at 11:41 AM
The second method does the same but also
optimizes all other codons using the 44 best codons identified in our
previously published efficiency codon metric (doi.org/10.1038/natu...). The last method (AG29G) follows a similar
approach but utilizes only the 29 best codons.
optimizes all other codons using the 44 best codons identified in our
previously published efficiency codon metric (doi.org/10.1038/natu...). The last method (AG29G) follows a similar
approach but utilizes only the 29 best codons.
The first
optimization method (AGhead) focuses solely on the first codons to increase the
ratio of adenosine to guanosine.
optimization method (AGhead) focuses solely on the first codons to increase the
ratio of adenosine to guanosine.
Codon influence on protein expression in E. coli correlates with mRNA levels - Nature
In-depth analyses of protein expression studies are used to derive a new codon-influence metric that correlates with global protein levels, mRNA levels and mRNA lifetimes in vivo, indicating tight cou...
doi.org
March 3, 2025 at 11:41 AM
The first
optimization method (AGhead) focuses solely on the first codons to increase the
ratio of adenosine to guanosine.
optimization method (AGhead) focuses solely on the first codons to increase the
ratio of adenosine to guanosine.
The manuscript comes with a web server, opt.williams.edu, that allows for the prediction of expression for
a given DNA sequence and proposes three types of optimization.
a given DNA sequence and proposes three types of optimization.
OPT codon optimization
opt.williams.edu
March 3, 2025 at 11:40 AM
The manuscript comes with a web server, opt.williams.edu, that allows for the prediction of expression for
a given DNA sequence and proposes three types of optimization.
a given DNA sequence and proposes three types of optimization.
We are all the same super family 🥰
March 1, 2025 at 8:19 PM
We are all the same super family 🥰
Thanks to @onamy.bsky.social for the code 🙏
January 3, 2024 at 12:42 PM
Thanks to @onamy.bsky.social for the code 🙏