Reposted
In the BEYOND study (308 participants, median age 45), 97% had viral load <50 copies/mL at 12 months. 97% preferred CAB+RPV LA over oral therapy. Treatment challenges decreased significantly. 📉💊##idsky
Clinical Outcomes and Perspectives of People With HIV-1 12 Months After Initiation of Long-acting Cabotegravir and Rilpivirine in an Observational Real-World US Study (BEYOND)
Long-acting c abotegravir + rilpivirine (CAB+RPV LA) administered monthly or every 2 months is recommended by treatment guidelines for maintenance of virologic suppression in people with HIV-1. In clinical trials, CAB+RPV LA demonstrated non-inferiority versus FDA-approved daily oral therapy, and outcomes in real-world settings can supplement these results. We present Month 12 results of BEYOND.MethodsBEYOND is an ongoing, 2-year, multicenter, prospective, observational real-world study of adults initiating CAB+RPV LA in the United States. Key outcomes included reasons for initiating, virologic outcomes, adherence, and patient-reported outcomes related to treatment satisfaction and treatment challenges at baseline and Month 12.ResultsIn total, 308 participants (median age, 45 years; 83% identified as male; 39% identified as Black) initiated CAB+RPV LA most commonly because of treatment fatigue, adherence anxiety with daily oral therapy, and/or convenience. Of participants with baseline viral load data, 97% (194/200) had a viral load <50 copies/mL for their most recent test reported at Month 12. Mean treatment satisfaction scores increased significantly from baseline to Month 12 and 97% (223/229) of participants preferred LA versus oral treatment at Month 12. Proportions of participants reporting “always” or “often” experiencing challenges related to HIV-1 treatment (fear of disclosure, adherence anxiety, reminder of HIV-1 status, and feeling stigmatized) decreased from baseline to Month 12.ConclusionsMonth 12 results from the real-world BEYOND study support the effectiveness of CAB+RPV LA for maintenance of virologic suppression and as a preferred treatment option for people with HIV-1.
academic.oup.com
April 20, 2025 at 1:00 AM
In the BEYOND study (308 participants, median age 45), 97% had viral load <50 copies/mL at 12 months. 97% preferred CAB+RPV LA over oral therapy. Treatment challenges decreased significantly. 📉💊##idsky
Reposted
🚨TARIFF UPDATE:
Tariffs are non-negotiable, negotiable, but not a negotiating tactic. They are permanent until they are paused but they will never be paused, until they are paused which means they increase. Permanent exemptions already announced are temporary, but nothing has been announced.
🤡🎪
Tariffs are non-negotiable, negotiable, but not a negotiating tactic. They are permanent until they are paused but they will never be paused, until they are paused which means they increase. Permanent exemptions already announced are temporary, but nothing has been announced.
🤡🎪
April 13, 2025 at 8:24 PM
🚨TARIFF UPDATE:
Tariffs are non-negotiable, negotiable, but not a negotiating tactic. They are permanent until they are paused but they will never be paused, until they are paused which means they increase. Permanent exemptions already announced are temporary, but nothing has been announced.
🤡🎪
Tariffs are non-negotiable, negotiable, but not a negotiating tactic. They are permanent until they are paused but they will never be paused, until they are paused which means they increase. Permanent exemptions already announced are temporary, but nothing has been announced.
🤡🎪
Reposted
Vancomycin Taper trial presented by @dremilymcd.bsky.social #ESCMID2025. In people who get better by day 10 should we stop or give taper? Reduced recurrences by primary outcome timepoint but the KM suggests it may be just delaying rather than truly preventing recurrence? #IDSky
April 13, 2025 at 3:38 PM
Vancomycin Taper trial presented by @dremilymcd.bsky.social #ESCMID2025. In people who get better by day 10 should we stop or give taper? Reduced recurrences by primary outcome timepoint but the KM suggests it may be just delaying rather than truly preventing recurrence? #IDSky
Reposted
In 25 years of covering national security, I’ve never seen a story like this: Senior Trump officials discussed planning for the U.S. attack on Yemen in a Signal group--and inadvertently added the editor-in-chief of The Atlantic. www.theatlantic.com/politics/arc...
The Trump Administration Accidentally Texted Me Its War Plans
U.S. national-security leaders included me in a group chat about upcoming military strikes in Yemen. I didn’t think it could be real. Then the bombs started falling.
www.theatlantic.com
March 24, 2025 at 4:11 PM
In 25 years of covering national security, I’ve never seen a story like this: Senior Trump officials discussed planning for the U.S. attack on Yemen in a Signal group--and inadvertently added the editor-in-chief of The Atlantic. www.theatlantic.com/politics/arc...
Reposted
@kkjetelina.bsky.social
Your measles FAQ is very useful and timely, thank you!
I've been searching PubMed, etc. looking for clear recommendations, guidelines, data for measles boosters by year vaccinated like you show in your table in the FAQ. Where did you find that data?
#primarycare #IDsky
Your measles FAQ is very useful and timely, thank you!
I've been searching PubMed, etc. looking for clear recommendations, guidelines, data for measles boosters by year vaccinated like you show in your table in the FAQ. Where did you find that data?
#primarycare #IDsky
10 FAQs on MMR and Measles Protection
Boosters, waning immunity, checking titers, infection induced immunity, and more
yourlocalepidemiologist.substack.com
March 14, 2025 at 10:56 PM
@kkjetelina.bsky.social
Your measles FAQ is very useful and timely, thank you!
I've been searching PubMed, etc. looking for clear recommendations, guidelines, data for measles boosters by year vaccinated like you show in your table in the FAQ. Where did you find that data?
#primarycare #IDsky
Your measles FAQ is very useful and timely, thank you!
I've been searching PubMed, etc. looking for clear recommendations, guidelines, data for measles boosters by year vaccinated like you show in your table in the FAQ. Where did you find that data?
#primarycare #IDsky
Reposted
MAGA influencers are out in full force tonight, making up things that were not in this resolution.
Congrats on getting your $4.5 trillion in tax cuts for the wealthy, $19 trillion in added deficit spending, and $880 billion in Medicaid cuts through this initial step, though.
Congrats on getting your $4.5 trillion in tax cuts for the wealthy, $19 trillion in added deficit spending, and $880 billion in Medicaid cuts through this initial step, though.
February 26, 2025 at 6:09 AM
MAGA influencers are out in full force tonight, making up things that were not in this resolution.
Congrats on getting your $4.5 trillion in tax cuts for the wealthy, $19 trillion in added deficit spending, and $880 billion in Medicaid cuts through this initial step, though.
Congrats on getting your $4.5 trillion in tax cuts for the wealthy, $19 trillion in added deficit spending, and $880 billion in Medicaid cuts through this initial step, though.
Reposted
We are absolutely not prepared for emerging threats—just look at the Texas measles outbreak.
Over 120 cases, spread to another state, and yet silence from the CDC, HHS Secretary, and other government agencies while dismantling ACIP and public health in this country.
Over 120 cases, spread to another state, and yet silence from the CDC, HHS Secretary, and other government agencies while dismantling ACIP and public health in this country.
Staff and observers worry that the agency may not be prepared for emerging threats including bird flu and insect-borne diseases.
Upheaval and firings at CDC raise fears about disease outbreak response
Staff and observers worry that the agency may not be prepared for emerging threats including bird flu and insect-borne diseases.
www.npr.org
February 26, 2025 at 1:41 PM
We are absolutely not prepared for emerging threats—just look at the Texas measles outbreak.
Over 120 cases, spread to another state, and yet silence from the CDC, HHS Secretary, and other government agencies while dismantling ACIP and public health in this country.
Over 120 cases, spread to another state, and yet silence from the CDC, HHS Secretary, and other government agencies while dismantling ACIP and public health in this country.
Reposted
Enjoy the listeria coming our way, and remember to thank this guy
Scoop: As federal health agencies are gutted, Kyle Diamantas, a Florida attorney w/ a slim resume + no prior gov't experience, is the new head of food safety at @US_FDA. Turns out, he's Donald Trump Jr.'s hunting buddy, @vanityfair.com is reporting exclusively: www.vanityfair.com/news/story/f... /1
America’s Food Safety Is Now in the Hands of Don Jr.’s Hunting Buddy
As federal health agencies are gutted with abandon, a Florida attorney with a history of hunting with the president’s son has been put in charge of food safety at the FDA, overseeing the nation’s food...
www.vanityfair.com
February 25, 2025 at 2:58 AM
Enjoy the listeria coming our way, and remember to thank this guy
Reposted
Russia invaded the sovereign nation of Ukraine. Vladimir Putin is the aggressor. I’m not going to let Trump rewrite history.
Balint: And now the United States stands with Russia and North Korea against Ukraine and all of our allies in Europe? It’s sick
February 25, 2025 at 1:45 PM
Russia invaded the sovereign nation of Ukraine. Vladimir Putin is the aggressor. I’m not going to let Trump rewrite history.
Reposted
This is an extremely interesting analysis.
The DOGE firings have nothing to do with “efficiency” or “cutting waste.” They’re a direct push to weaken federal agencies perceived as liberal. This was evident from the start, and now the data confirms it: targeted agencies overwhelmingly those seen as more left-leaning. 🧵⬇️
February 20, 2025 at 1:34 PM
This is an extremely interesting analysis.
Reposted
NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%.
https://propub.li/43487Tj
https://propub.li/43487Tj
Texas Banned Abortion. Then Sepsis Rates Soared.
ProPublica’s first-of-its-kind analysis is the most detailed look yet into a rise in life-threatening complications for women experiencing pregnancy loss under Texas’ abortion ban.
propub.li
February 20, 2025 at 12:00 PM
NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%.
https://propub.li/43487Tj
https://propub.li/43487Tj
Reposted
"Law and order" in the Trump era: if you bow down to the head of the U.S. government, he may help you - whether you're awaiting trial for sex crimes in Europe or doing time in the USA for physically assaulting police.
February 18, 2025 at 2:45 AM
"Law and order" in the Trump era: if you bow down to the head of the U.S. government, he may help you - whether you're awaiting trial for sex crimes in Europe or doing time in the USA for physically assaulting police.
Reposted
JUST IN: Another medical horror story in an affidavit from a USAID employee stationed overseas. Says his pregnant wife was not medevac-ed for emergency health care because of directives from DC. Took intervention of a U.S. senator to reverse — but was too late. s3.documentcloud.org/documents/25...
February 18, 2025 at 1:40 AM
JUST IN: Another medical horror story in an affidavit from a USAID employee stationed overseas. Says his pregnant wife was not medevac-ed for emergency health care because of directives from DC. Took intervention of a U.S. senator to reverse — but was too late. s3.documentcloud.org/documents/25...
Reposted
This is why you fight these cowards.
The moment you stand up to them, they crumble.
Homan has nothing. The Fourth Amendment is clear and I am well within my duties to educate people of their rights.
He can threaten me with jail and call names all he wants. He’s got nothing else.
The moment you stand up to them, they crumble.
Homan has nothing. The Fourth Amendment is clear and I am well within my duties to educate people of their rights.
He can threaten me with jail and call names all he wants. He’s got nothing else.
a stammering Tom Homan on AOC: "She's the dumbest congresswoman ever elected to Congress."
February 18, 2025 at 3:17 AM
This is why you fight these cowards.
The moment you stand up to them, they crumble.
Homan has nothing. The Fourth Amendment is clear and I am well within my duties to educate people of their rights.
He can threaten me with jail and call names all he wants. He’s got nothing else.
The moment you stand up to them, they crumble.
Homan has nothing. The Fourth Amendment is clear and I am well within my duties to educate people of their rights.
He can threaten me with jail and call names all he wants. He’s got nothing else.
Reposted
1/29: First plane crash in 16 years in DC
1/31: Crash in Philly
2/5: Delta flight struck in Seattle
2/6: Flight wrecks in Alaska
2/10: Crash in Scottsdale
2/12: Military jet crashes in San Diego
2/16: Crash in Covington, GA
7 crashes since the WH congratulated itself for “restoring aviation safety”
1/31: Crash in Philly
2/5: Delta flight struck in Seattle
2/6: Flight wrecks in Alaska
2/10: Crash in Scottsdale
2/12: Military jet crashes in San Diego
2/16: Crash in Covington, GA
7 crashes since the WH congratulated itself for “restoring aviation safety”
February 16, 2025 at 3:01 PM
1/29: First plane crash in 16 years in DC
1/31: Crash in Philly
2/5: Delta flight struck in Seattle
2/6: Flight wrecks in Alaska
2/10: Crash in Scottsdale
2/12: Military jet crashes in San Diego
2/16: Crash in Covington, GA
7 crashes since the WH congratulated itself for “restoring aviation safety”
1/31: Crash in Philly
2/5: Delta flight struck in Seattle
2/6: Flight wrecks in Alaska
2/10: Crash in Scottsdale
2/12: Military jet crashes in San Diego
2/16: Crash in Covington, GA
7 crashes since the WH congratulated itself for “restoring aviation safety”
Reposted
If you wanted to cut waste, fraud, and abuse, you would empower the inspectors general.
If you wanted more waste, fraud, and abuse, you would fire them.
If you wanted more waste, fraud, and abuse, you would fire them.
February 17, 2025 at 2:17 PM
If you wanted to cut waste, fraud, and abuse, you would empower the inspectors general.
If you wanted more waste, fraud, and abuse, you would fire them.
If you wanted more waste, fraud, and abuse, you would fire them.
Reposted
Reposted
I fear they’re coming for ALL school vaccine mandates next. Including measles, mumps and rubella.
February 15, 2025 at 3:32 PM
I fear they’re coming for ALL school vaccine mandates next. Including measles, mumps and rubella.
Reposted
the single most un-american and anti-constitutional statement ever uttered by an american president
February 15, 2025 at 6:39 PM
the single most un-american and anti-constitutional statement ever uttered by an american president
Reposted
This is a very heavy day for us.
To those who lost their jobs, we are with you and will work with you again.
To those struggling to see a future for our work, do not give up.
Real change in public health has always been a battle. Now it’s a war.
We will win it.
This is our country. #RISEUP
To those who lost their jobs, we are with you and will work with you again.
To those struggling to see a future for our work, do not give up.
Real change in public health has always been a battle. Now it’s a war.
We will win it.
This is our country. #RISEUP
ACT UP’s Radical Activism Saved Lives During the AIDS Epidemic
The movement stood up to the president, pharmaceutical companies, and the CDC.
www.teenvogue.com
February 14, 2025 at 9:57 PM
This is a very heavy day for us.
To those who lost their jobs, we are with you and will work with you again.
To those struggling to see a future for our work, do not give up.
Real change in public health has always been a battle. Now it’s a war.
We will win it.
This is our country. #RISEUP
To those who lost their jobs, we are with you and will work with you again.
To those struggling to see a future for our work, do not give up.
Real change in public health has always been a battle. Now it’s a war.
We will win it.
This is our country. #RISEUP
Reposted
This is so smart. @petebuttigieg.bsky.social , thoughts ?
And if you see this. A reminder. This is not Twitter. You can engage here and have thoughtful discussions !
We all look forward to reading your thoughts
And if you see this. A reminder. This is not Twitter. You can engage here and have thoughtful discussions !
We all look forward to reading your thoughts
I keep saying Dems need to do a daily briefing on Capitol Hill and fill the void, fact check the WH. Hire Pete Buttigeig and give him a staff to do this.
February 14, 2025 at 6:15 PM
This is so smart. @petebuttigieg.bsky.social , thoughts ?
And if you see this. A reminder. This is not Twitter. You can engage here and have thoughtful discussions !
We all look forward to reading your thoughts
And if you see this. A reminder. This is not Twitter. You can engage here and have thoughtful discussions !
We all look forward to reading your thoughts
Reposted
It is perfectly legal to know your rights and to educate others about them, too.
EVERYONE in the United States, citizen or not, has rights. I will not allow this administration to intimidate us from helping you know about them.
Here’s our shareable guide ⬇️: (pt. 1/2)
EVERYONE in the United States, citizen or not, has rights. I will not allow this administration to intimidate us from helping you know about them.
Here’s our shareable guide ⬇️: (pt. 1/2)
February 14, 2025 at 11:47 PM
It is perfectly legal to know your rights and to educate others about them, too.
EVERYONE in the United States, citizen or not, has rights. I will not allow this administration to intimidate us from helping you know about them.
Here’s our shareable guide ⬇️: (pt. 1/2)
EVERYONE in the United States, citizen or not, has rights. I will not allow this administration to intimidate us from helping you know about them.
Here’s our shareable guide ⬇️: (pt. 1/2)
Reposted
DISEASES ERADICATED OR DECIMATED BY SCIENCE:
1. Chickenpox
2. Diphtheria
3. Measles
4. Pertussis
5. Pneumococcal Infection
6. Polio
7. Tetanus
8. Typhoid
9. Yellow Fever
10. Smallpox
DISEASES ERADICATED OR DECIMATED BY RFK JR. OR PRAYER:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
1. Chickenpox
2. Diphtheria
3. Measles
4. Pertussis
5. Pneumococcal Infection
6. Polio
7. Tetanus
8. Typhoid
9. Yellow Fever
10. Smallpox
DISEASES ERADICATED OR DECIMATED BY RFK JR. OR PRAYER:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
February 13, 2025 at 5:05 PM
DISEASES ERADICATED OR DECIMATED BY SCIENCE:
1. Chickenpox
2. Diphtheria
3. Measles
4. Pertussis
5. Pneumococcal Infection
6. Polio
7. Tetanus
8. Typhoid
9. Yellow Fever
10. Smallpox
DISEASES ERADICATED OR DECIMATED BY RFK JR. OR PRAYER:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
1. Chickenpox
2. Diphtheria
3. Measles
4. Pertussis
5. Pneumococcal Infection
6. Polio
7. Tetanus
8. Typhoid
9. Yellow Fever
10. Smallpox
DISEASES ERADICATED OR DECIMATED BY RFK JR. OR PRAYER:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
Reposted
July 1, 1946 CDC was created, in the heart of the south, to combat malaria in the US. That year there were ~48,610 US malaria cases. With the help of WHO and others, CDC established case reporting, investigation, and preventative measures. By 1957, endemic malaria had been eradicated in the US.
February 13, 2025 at 3:18 AM
July 1, 1946 CDC was created, in the heart of the south, to combat malaria in the US. That year there were ~48,610 US malaria cases. With the help of WHO and others, CDC established case reporting, investigation, and preventative measures. By 1957, endemic malaria had been eradicated in the US.
Reposted
BREAKING
On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders
On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.
On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders
On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.
BREAKING: NIH admits funding freeze is illegal, will resume issuing grants
An internal memo issued February 12 was obtained by Popular Information.
popular.info
February 12, 2025 at 7:36 PM
BREAKING
On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders
On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.
On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders
On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.