biorealism.bsky.social
@biorealism.bsky.social
You see also some of the most cited papers like Pekar et al (2022) supporting multiple spillovers appear to have serious flaws and may need to be retracted. @mbweissman.bsky.social arxiv.org/abs/2510.01484
Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to human...
arxiv.org
November 13, 2025 at 10:36 AM
Ultimately, as Jesse Bloom has explained, the early case data is hopelessly biased. If it began in Wuhan WIV's sampling history in Yunnan and Laos provides a potential link. The NIH terminated WIV's subaward for refusal to share records of their SrCoV research. academic.oup.com/mbe/article/...
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academic.oup.com
November 13, 2025 at 10:29 AM
Reposted
Wait- that's all stuff from Pekar 2022, the paper with enormous math errors that you just said was irrelevant. When those errors are fixed, its 2-spill probability becomes low, which undercuts its whole story. Tho P(other zoo stories) is unaffected by market-story errors.
November 3, 2025 at 11:30 PM
Reposted
By that token anything by anyone who cites anything by any of the 29 authors of Pekar et al. 2022 would have to be presumed false. Let's stick to the specific points. Here the only relevant one is whether leaving RE sites in eases making a series of partial new clones.
November 3, 2025 at 6:48 PM
Reposted
It was, in fact, a very good job by Brookings.
See michaelweissman.substack.com/p/an-inconve... for a (long) systematic summary of the evidence. For bite-size published refutations of the key zoonotic claims:
doi.org/10.1093/jrss...
doi.org/10.1093/jrss...
academic.oup.com/ve/article/1...
Importance of quantifying the number of viral reads in metagenomic sequencing of environmental samples from the Huanan Seafood Market
Abstract. In March 2023, the Chinese CDC publicly released raw metagenomic sequencing data for environmental samples collected in early 2020 from the Huana
academic.oup.com
October 28, 2025 at 2:13 AM
It's icky although the implications are hardly any worse than those for AI (mass unemployment, potential extinction).
October 23, 2025 at 2:51 AM
Reposted
Bloom again on evidence of bias in the early sequences and why the root of the SARS-CoV-2 tree cannot be conclusively resolved with the current data.
academic.oup.com/mbe/article/...
October 22, 2025 at 9:38 AM
Reposted
Who is conflicted in this scenario? There are obviously significant limitations with early case data which George Gao acknowledged was biased towards the market. The multiple spillover theory rests on a flawed analysis at odds with the analyses of Bloom, Kumar and Lv et al.
arxiv.org/abs/2510.01484
Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to human...
arxiv.org
October 22, 2025 at 9:34 AM
Reposted
Very interesting. “one of the greatest lessons of the last five years is that public health needs to step up its game in dealing with uncertainty.”
October 22, 2025 at 6:47 AM
Ultimately the early case data is highly biased and the root of the SARS-CoV-2 tree cannot be conclusively resolved with the current data. academic.oup.com/mbe/article/...
The Data are Insufficient to Confidently Root the SARS-CoV-2 Phylogenetic Tree
Abstract. Several years ago, I published a paper that described the discrepancy between outgroup and date-based methods for rooting the SARS-CoV-2 phylogen
academic.oup.com
October 22, 2025 at 9:40 AM
Bloom again on evidence of bias in the early sequences and why the root of the SARS-CoV-2 tree cannot be conclusively resolved with the current data.
academic.oup.com/mbe/article/...
October 22, 2025 at 9:38 AM
Who is conflicted in this scenario? There are obviously significant limitations with early case data which George Gao acknowledged was biased towards the market. The multiple spillover theory rests on a flawed analysis at odds with the analyses of Bloom, Kumar and Lv et al.
arxiv.org/abs/2510.01484
Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to human...
arxiv.org
October 22, 2025 at 9:34 AM
A number of those who have argued it is resolved seem unaware of the limitations of the early case data and apparent flaws in much cited papers like Pekar et al. @mbweissman.bsky.social arxiv.org/abs/2510.01484
Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to human...
arxiv.org
October 22, 2025 at 6:53 AM
Jane Qui wrote recently about how a lack of transparency and overconfident conclusions in relation to the origin of COVID-19 has undermined trust in science.
www.theguardian.com/commentisfre...
The Covid ‘lab leak’ theory isn’t just a rightwing conspiracy – pretending that’s the case is bad for science | Jane Qiu
While figures like Steve Bannon have exploited the issue, scientists have done themselves no favours by shutting down legitimate inquiry, says award-winning science writer Jane Qiu
www.theguardian.com
October 22, 2025 at 6:50 AM