Binyam Mogessie ቢንያም ሞገሴ
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binyammogessie.bsky.social
Binyam Mogessie ቢንያም ሞገሴ
@binyammogessie.bsky.social
Asst. Prof @Yale studying eggs, chromosomes and human infertility. Wellcome Trust Sir Henry Dale Fellow. Homepage: https://eggsnchromosomes.org
#actin #microtubules #oocytes #meiosis #FemaleReproductiveAging #QuantitativeCellBiology
We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨
With @jiyeonleem.bsky.social and our team at Yale MCDB.

Read: www.nature.com/articles/s43...
A versatile cohesion manipulation system probes female reproductive age-related egg aneuploidy - Nature Aging
To study pathways that lead to aneuploidy during aging, the authors provide a system that enables cohesion protein depletion in mouse oocytes, mimicking effects that occur during aging. They uncover a...
www.nature.com
November 4, 2025 at 1:17 PM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
Some good news during these difficult times. Please check out our new preprint. We built a new tool to probe the origins of high oocyte aneuploidy rates at advanced female reproductive ages. This NIH funded work was led by a fantastic postdoc in the lab, Jiyeon Leem. www.biorxiv.org/content/10.1...
A versatile cohesion manipulation system reveals CENP-A dysfunction accelerates female reproductive age-related egg aneuploidy.
Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromosome cohesion proteins and untimely separation of chromosomes is thought to unde...
www.biorxiv.org
February 28, 2025 at 12:39 PM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
Sharing some oocyte spindle love-an image taken by PhD student Phia Maddocks. This beautiful work is supported by our NIH funding. Without this funding, we cannot understand the complexities of fertility genetics. With declining fertility rates, this work is essential to human health.
January 29, 2025 at 9:42 PM
This is couple of years old since I rarely have time to sit at a scope these days but I was inspired by the end of year #FluorescenceFriday posts on hear and thought I should drop on y’all my Eye of Sauron, aka a mouse oocyte containing nuclear actin filaments #actin #meiosis #oocytes
December 20, 2024 at 10:57 PM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
Happy to see this out before the end of the year. Fantastic work by Lily Wang with help from our wonderful technologists in the Discovery Platform Proteomics Core managed by Christos Spanos. Great publishing experience @embojournal.bsky.social www.embopress.org/doi/full/10....
Molecular mechanism targeting condensin for chromosome condensation | The EMBO Journal
imageimageHow the condensin complex is recruited to genomic domains to promote their condensation is incompletely understood. This study identifies a generalised molecular mechanism by which condensin...
www.embopress.org
December 18, 2024 at 10:06 AM
Chromosome segregation errors are common in the early stages of human embryonic development. Read here our open access commentary on three recent studies of spindle architecture and positioning features that
could provide insights into why early embryos are predisposed to aneuploidy.
rdcu.be/d1TgG
On the origin of mitosis-derived human embryo aneuploidy
Nature Communications - Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell...
rdcu.be
November 29, 2024 at 2:29 PM
My lab came as me for Halloween…i’m proud 🥹
October 27, 2023 at 6:46 PM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
Yale University and the Department of Molecular, Cellular and Developmental Biology is looking for Assistant Professor in Plant Biology and Assistant Professor in Systems Biology.
#neurojobs
#neuroscience l🧪l🧠📊l🧠🖥️
#academicsky
#statsky
#physics
mcdb.yale.edu
October 8, 2023 at 2:48 AM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
The Department of Molecular, Cellular and Developmental Biology at Yale University is looking for a

Tenure-track Assistant Professor in Plant Biology

mcdb.yale.edu

PDF:
mcdb.yale.edu/sites/defaul...

#PlantSciJobs

FEED for Plant Science Jobs here:

bsky.app/profile/did:...
Welcome | Molecular, Cellular and Developmental Biology
mcdb.yale.edu
September 22, 2023 at 7:51 AM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
Come be my colleague! The MCB Department at UConn is looking for a TT Assistant Professor in the broad fields of structural biology, biophysics, and biochemistry. Collaborative department, strong graduate program, and state of the art core facilities. academicjobsonline.org/ajo/jobs/25945
September 27, 2023 at 1:35 PM
Reposted by Binyam Mogessie ቢንያም ሞገሴ
Excited to host @binyammogessie.bsky.social at UConn MCB tomorrow! Looking forward to nerding out about eggs and chromosomes 🧬🔬🥚
October 2, 2023 at 9:54 PM