Binyam Mogessie ቢንያም ሞገሴ
@binyammogessie.bsky.social
Asst. Prof @Yale studying eggs, chromosomes and human infertility. Wellcome Trust Sir Henry Dale Fellow. Homepage: https://eggsnchromosomes.org
#actin #microtubules #oocytes #meiosis #FemaleReproductiveAging #QuantitativeCellBiology
#actin #microtubules #oocytes #meiosis #FemaleReproductiveAging #QuantitativeCellBiology
We built an experimental system for manipulation of oocyte chromosome cohesion using PROTACs, mimicking within 1.5 hrs chromosomal abnormalities that naturally arise over years to decades. BONUS: we visualized by live imaging chromosome arm-specific and centromeric retention of REC8 during anaphase!
February 28, 2025 at 12:43 PM
We built an experimental system for manipulation of oocyte chromosome cohesion using PROTACs, mimicking within 1.5 hrs chromosomal abnormalities that naturally arise over years to decades. BONUS: we visualized by live imaging chromosome arm-specific and centromeric retention of REC8 during anaphase!