🚨review paper alert: non-invasive prenatal screening (NIPS) traditionally predicts common trisomies.
NIPS data however also contains genetic signal to predict additional complications: malignancies, rare autosomal trisomies confined to the placenta, monogenic disorders and common genetic risks.
NIPS data however also contains genetic signal to predict additional complications: malignancies, rare autosomal trisomies confined to the placenta, monogenic disorders and common genetic risks.
Expanding the scope of non-invasive prenatal screening
Nature Genetics - Cell-free DNA from non-invasive prenatal screening reflects the maternal and fetal genome and epigenome. This Review discusses its analysis for actionable pregnancy complication...
rdcu.be
October 17, 2025 at 2:26 PM
🚨review paper alert: non-invasive prenatal screening (NIPS) traditionally predicts common trisomies.
NIPS data however also contains genetic signal to predict additional complications: malignancies, rare autosomal trisomies confined to the placenta, monogenic disorders and common genetic risks.
NIPS data however also contains genetic signal to predict additional complications: malignancies, rare autosomal trisomies confined to the placenta, monogenic disorders and common genetic risks.
Reposted by Bernard Thienpont
Methods and applications for single-cell and spatial multi-omics go.nature.com/3GkzmzZ #Review by Katy Vandereyken, Alejandro Sifrim, @bernthie.bsky.social & Thierry Voet
Free to read here: rdcu.be/c6JjL
Free to read here: rdcu.be/c6JjL
Methods and applications for single-cell and spatial multi-omics
Nature Reviews Genetics - In this Review, the authors discuss the latest advances in profiling multiple molecular modalities from single cells, including genomic, transcriptomic, epigenomic and...
rdcu.be
June 27, 2025 at 8:30 AM
Methods and applications for single-cell and spatial multi-omics go.nature.com/3GkzmzZ #Review by Katy Vandereyken, Alejandro Sifrim, @bernthie.bsky.social & Thierry Voet
Free to read here: rdcu.be/c6JjL
Free to read here: rdcu.be/c6JjL
Reposted by Bernard Thienpont
Honoured to see an article about my research on extra-pair paternity in @science.org. Many thanks to journalist @spoke32.bsky.social for the story and to all colleagues for their quotes!
Hopefully, future visitors to my office will be less surprised by a (reproduction) 17th-century painting...
Hopefully, future visitors to my office will be less surprised by a (reproduction) 17th-century painting...
How often are children genetically unrelated to their presumed fathers?
Tackling a touchy subject, genetic detective finds only 1% of European children have unexpected paternity
www.science.org
March 7, 2025 at 11:03 PM
Honoured to see an article about my research on extra-pair paternity in @science.org. Many thanks to journalist @spoke32.bsky.social for the story and to all colleagues for their quotes!
Hopefully, future visitors to my office will be less surprised by a (reproduction) 17th-century painting...
Hopefully, future visitors to my office will be less surprised by a (reproduction) 17th-century painting...
Reposted by Bernard Thienpont
🚨The final deadline to register for #RNGS25 is this Wednesday, March 5th!🚨
Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬
www.vibconferences.be/events/revol...
Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬
www.vibconferences.be/events/revol...
March 3, 2025 at 10:33 AM
🚨The final deadline to register for #RNGS25 is this Wednesday, March 5th!🚨
Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬
www.vibconferences.be/events/revol...
Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬
www.vibconferences.be/events/revol...
Reposted by Bernard Thienpont
Review alert - "Modelling and design of transcriptional enhancers" by Seppe and Vasilis 👇
We wrote a review article on modelling and design of transcriptional enhancers using sequence-to-function models.
From conventional machine learning methods to CNNs and using models as oracles/generative AI for synthetic enhancer design!
@natrevbioeng.bsky.social
www.nature.com/articles/s44...
From conventional machine learning methods to CNNs and using models as oracles/generative AI for synthetic enhancer design!
@natrevbioeng.bsky.social
www.nature.com/articles/s44...
Modelling and design of transcriptional enhancers - Nature Reviews Bioengineering
Enhancers are genomic elements critical for regulating gene expression. In this Review, the authors discuss how sequence-to-function models can be used to unravel the rules underlying enhancer activit...
www.nature.com
February 28, 2025 at 4:53 PM
Review alert - "Modelling and design of transcriptional enhancers" by Seppe and Vasilis 👇
📢 #JobAlert We are looking for a lab technician. You can contribute to various interesting research projects. Apply before 11/03:
kuleuven.be/personeel/jo...
kuleuven.be/personeel/jo...
Laboratoriumtechnoloog (Lab technician)
Een gevarieerde functie in een boeiende onderzoeksomgeving!
kuleuven.be
February 20, 2025 at 7:26 PM
📢 #JobAlert We are looking for a lab technician. You can contribute to various interesting research projects. Apply before 11/03:
kuleuven.be/personeel/jo...
kuleuven.be/personeel/jo...
Reposted by Bernard Thienpont
In the most recent episode we talked with @vonmeyennlab.bsky.social from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. #podcast #epigenetics #chromatin
Listen here: https://buff.ly/4jmwK3j
Listen here: https://buff.ly/4jmwK3j
January 27, 2025 at 9:00 AM
In the most recent episode we talked with @vonmeyennlab.bsky.social from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. #podcast #epigenetics #chromatin
Listen here: https://buff.ly/4jmwK3j
Listen here: https://buff.ly/4jmwK3j
Reposted by Bernard Thienpont
Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII
Predicting ‘male-time’ with the Androgen Clock
YouTube video by Epigenetics Otago
youtu.be
January 26, 2025 at 7:00 PM
Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII
Reposted by Bernard Thienpont
Finding new folks to follow: try out this tool. bsky-follow-finder.theo.io
Bluesky Network Analyzer
Find accounts that you don't follow (yet) but are followed by lots of accounts that you do follow.
bsky-follow-finder.theo.io
January 21, 2025 at 4:21 PM
Finding new folks to follow: try out this tool. bsky-follow-finder.theo.io
Reposted by Bernard Thienpont
🧬Today is your last chance to submit your research for #RNGS25, the leading European #sequencing conference. Present your work on stage or during the poster sessions.
Submit it before midnight (CET) tonight here: vibbio.tech/40g5N8P #NGS #multiomics #genomics #epigenomics
Submit it before midnight (CET) tonight here: vibbio.tech/40g5N8P #NGS #multiomics #genomics #epigenomics
January 15, 2025 at 8:14 AM
🧬Today is your last chance to submit your research for #RNGS25, the leading European #sequencing conference. Present your work on stage or during the poster sessions.
Submit it before midnight (CET) tonight here: vibbio.tech/40g5N8P #NGS #multiomics #genomics #epigenomics
Submit it before midnight (CET) tonight here: vibbio.tech/40g5N8P #NGS #multiomics #genomics #epigenomics
very elegant approach to in vivo CRISPR screens!
Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology.
1/
www.nature.com/articles/s41...
1/
www.nature.com/articles/s41...
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology
Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.
www.nature.com
December 22, 2024 at 4:50 PM
very elegant approach to in vivo CRISPR screens!
Looking forward to meeting you all in Antwerp!
Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/4iJMnS0
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML
December 18, 2024 at 3:56 PM
Looking forward to meeting you all in Antwerp!
Reposted by Bernard Thienpont
Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/4iJMnS0
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML
December 18, 2024 at 2:32 PM
Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/4iJMnS0
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML
Present on stage with a poster pitch or during the poster sessions.
The abstract deadline is 15 January 2025.
#ngs #genomics #multiomics #epigenomics #AI #ML