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berlinliverlab.bsky.social
Rezvani Lab
@berlinliverlab.bsky.social
liver lovers | in vivo tissue reprogramming | stem cells | blood-liver development models | pediatric hepatology | Emmy Noether Lab | rezvanilab.org
Proud of my outstanding PhD students!

Independent of me, @julianweihs.bsky.social & Susanna Quach assembled with students from the Wagner lab in Berlin and won a Pitch Award for their idea to remove microplastics from cells.
@bihatcharite.bsky.social @einsteinberlin.bsky.social
November 6, 2025 at 11:53 AM
The liver balances immune tolerance and inflammation—but most liver models don’t.

In this new review, I break down human-specific systems to study liver–immune crosstalk.

From cocultures to organoids.

www.nature.com/articles/s41...

@bihatcharite.bsky.social
Human liver immunology: from in vitro models to new insights - Cellular & Molecular Immunology
Cellular & Molecular Immunology - Human liver immunology: from in vitro models to new insights
www.nature.com
July 2, 2025 at 2:35 PM
Reposted by Rezvani Lab
"Science is an investment.

We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world."

— President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷
May 5, 2025 at 10:16 AM
Reposted by Rezvani Lab
After every encounter with the current scientific publishing system
May 4, 2025 at 4:49 AM
So much fun at the @berlinliverlab.bsky.social outing — from laser tag battles to beers in the Berlin evening sun. Grateful for this brilliant, fun, and inspiring team! #LabLife #BerlinVibes @bihatcharite.bsky.social
May 2, 2025 at 5:24 AM
Reposted by Rezvani Lab
Who funds biomedical research? @nature.com
www.nature.com/articles/d41...
March 10, 2025 at 5:12 PM
Reposted by Rezvani Lab
New online! Clusters of metabolic dysfunction-associated steatotic liver disease for precision medicine
Clusters of metabolic dysfunction-associated steatotic liver disease for precision medicine
Nature Reviews Gastroenterology & Hepatology, Published online: 26 February 2025; doi:10.1038/s41575-025-01048-wMetabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous disease regarding its pathophysiology and clinical…
www.nature.com
February 26, 2025 at 10:29 AM
Reposted by Rezvani Lab
New online! Μetabolic dysfunction-associated steatotic liver disease: a condition of heterogeneous metabolic risk factors, mechanisms and comorbidities requiring holistic treatment
Μetabolic dysfunction-associated steatotic liver disease: a condition of heterogeneous metabolic risk factors, mechanisms and comorbidities requiring holistic treatment
Nature Reviews Gastroenterology & Hepatology, Published online: 17 February 2025; doi:10.1038/s41575-025-01045-zThis Review discusses the link between metabolic dysfunction-associated steatotic liver disease (MASLD) — a heterogeneous health condition —…
www.nature.com
February 18, 2025 at 3:44 AM
Reposted by Rezvani Lab
Check out this new article highlighting our postdoc @amandaanderssonr.bsky.social ’s work on a novel pancreatic organoid model that includes all three key cell types, offering new insights into pancreatic development: www.the-scientist.com/a-novel-thre...
A Novel Three-in-One Pancreatic Organoid
An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and possible regeneration.
www.the-scientist.com
February 13, 2025 at 11:31 AM
interesting.

Is PROX1 —a well established factor in liver development— also maintaining liver cell identity long after birth?

www.nature.com/articles/s41...
Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis - Nature Genetics
This study identifies candidate safeguard repressor transcription factors that repress alternate lineages in mature cell types and provides functional evidence that Prox1 performs such a function in h...
www.nature.com
February 13, 2025 at 3:35 PM
Reposted by Rezvani Lab
A new round of the Lise Meitner Excellence Program for #tenuretrack group leaders opened today - please consider applying! The program aims to recruit and promote exceptionally qualified female scientists. www.mpg.de/lise-meitner... #LiseMeitnerGroups #WomeninScience #ScienceCareer
February 12, 2025 at 2:46 PM
Reposted by Rezvani Lab
Die neue US-Administration schränkt die #Forschungsfreiheit ein – Förderanträge werden nicht geprüft, Mittel eingefroren. Das betrifft auch viele unserer Partner. Umso wichtiger ist es, den transatlantischen Austausch zu stärken. Gespräch im @spiegel.de u.a. dazu (€): www.spiegel.de/wissenschaft...
(S+) Deutschland und Donald Trump: Max-Planck-Gesellschaft wirbt um US-Spitzenforscher
Ist Deutschland am Ende Nutznießer von Trumps Feldzug gegen die Wissenschaft? Die Max-Planck-Gesellschaft meldet viel mehr Bewerbungen aus den USA als früher. Präsident Patrick Cramer will dort geziel...
www.spiegel.de
February 10, 2025 at 10:42 AM
Has writing scientific reviews just become obsolete?

…because AI does it better?

www.nature.com/articles/d41...

@maxplanck.de
OpenAI’s ‘deep research’ tool: is it useful for scientists?
The model produces cited, pages-long reports that might be helpful for generating literature reviews.
www.nature.com
February 10, 2025 at 6:29 AM
Reposted by Rezvani Lab
What do Europeans think of science and technology?

- 83% believe science and tech have a positive impact,
- 67% say science makes life easier, healthier and more comfortable,
- 58% want to learn more about scientific advances.

Find out more in the new Eurobarometer.
ec.europa.eu/commission/p...
Europeans strongly support science and technology according to new Eurobarometer survey
The latest Eurobarometer survey on ‘European citizens' knowledge and attitudes towards science and technology' released today shows more than 8 in 10 citizens (83%) think that the overall influence of...
ec.europa.eu
February 8, 2025 at 2:06 PM
Reposted by Rezvani Lab
Hello, Bluesky! ☀️

We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.

Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
February 7, 2025 at 8:16 AM
Lively discussions on Metabolic dysfunction-associated steatotic liver disease (MASLD) with scientists from Berlin and Dresden at Charité Berlin Crossover.

#BerlinInstituteofHealth #BIh
#TechnischeUniversitätDresden
#LiverResearch #MASLD #BerlinScience #Collaboration #Charité
February 7, 2025 at 6:31 PM
Reposted by Rezvani Lab
Cover letter when you're missing the mechanism
February 4, 2025 at 5:50 PM
🔔I take care of kids, not geriatrics, and I’m skeptical of the tech-bro #longevity obsession—but this study seems cool and cost-efficient!

If true, it suggests taking Vitamin D, algae-based Omega-3 + exercising 3x/week slows molecular aging by 3-4 months. Not bad!

www.nature.com/articles/s43...
Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial - Nature Aging
Applying epigenetic clocks to samples from the DO-HEALTH trial, Bischoff-Ferrari et al. report a small protective effect of omega-3 supplementation over 3 years on several clocks and an additive prote...
www.nature.com
February 3, 2025 at 5:50 PM
Reposted by Rezvani Lab
ICYMI: New online! Preventing the progression of cirrhosis to decompensation and death
Preventing the progression of cirrhosis to decompensation and death
Nature Reviews Gastroenterology & Hepatology, Published online: 27 January 2025; doi:10.1038/s41575-024-01031-xThis Review describes the progression of advanced chronic liver disease (ACLD) from its early stages (compensated ACLD) to more advanced disease…
www.nature.com
February 2, 2025 at 6:50 PM
Could fully biologic tissue-engineered blood vessels be the future of coronary bypass?

Promising work by Park et al. shows antithrombotic function & graft patency using hiPSC-ECs.

Thoughts?

www.cell.com/cell-stem-ce...

#RegenerativeMedicine #VascularBioengineering
www.cell.com
February 2, 2025 at 8:17 AM
Will there be a scientific Exodus to Germany from the US?

#NIH
#Trump
@maxplanck.de
@www.helmholtz.de
@harvard.edu
@harvardchanschool.bsky.social
January 31, 2025 at 3:41 PM
Encouraging.

Towards developing a new vaccine for urinary tract infections #UTIs.

I wonder if also applicable to children where #UTIs are a big problem

@ethzurich.bsky.social

ethz.ch/en/news-and-...
ETH Zurich researcher aims to prevent urinary tract infections with a vaccine
Every second woman and every eighth man suffer from urinary tract infections. These are painful and can recur with serious health consequences. Pioneer Fellow Giorgia Greter has a solution.
ethz.ch
January 31, 2025 at 10:30 AM
an alien with lipstick or a zebra fish heart.

both amazing
This is an image of a living zebrafish embryo with the heart visible, labelled with fluorescent proteins and taken using confocal #microscopy 🧪🔬

Image credits: Rashmi Priya and Srinivas Allanki
January 30, 2025 at 6:50 PM
AAVs are already used clinically🩻

This seems like a useful resource to make your experiments for translational
Many factors can affect serotype choice, so whatever your experiment, we recommend diving into the literature, understanding your variables, and always experimentally validating your AAV of choice.

blog.addgene.org/viral-vector...
Viral Vectors 101: AAV Variables That Matter
Learn about the process to select the optimal serotype, promoter, and titer for your AAV experiment.
blog.addgene.org
January 30, 2025 at 7:10 AM
mind. blown.

these peeps transplanted a bioengineered patch made from iPSCs and stromal into primates and a human and saw evidence for remuscularization.

www.nature.com/articles/s41...
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading ...
www.nature.com
January 29, 2025 at 5:08 PM