Benoît Zuber
@benoitzuber.bsky.social
Professor at University of Bern, Switzerland. Structural Biology, Neuroscience, and Toxins. #TeamTomo #CryoEM #DubochetCenterForImaging
Paper alert🚨
Label your protein of interest and localize it in cryoET 👁️❄️
Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...
Label your protein of interest and localize it in cryoET 👁️❄️
Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...
Genetically encoded FerriTag as a specific label for cryo-electron tomography
Wang et al. present an optimized labeling strategy for cryo-electron tomography based
on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded
ferritin to target proteins, en...
www.cell.com
September 11, 2025 at 9:36 AM
Paper alert🚨
Label your protein of interest and localize it in cryoET 👁️❄️
Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...
Label your protein of interest and localize it in cryoET 👁️❄️
Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...
Reposted by Benoît Zuber
We are hiring-join us!
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
September 8, 2025 at 10:31 AM
We are hiring-join us!
In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...
July 4, 2025 at 7:50 AM
In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...
🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins
doi.org/10.1101/2025...
A plain language overview of our recent publication link.growkudos.com/1bt0psurksg
Near-atomic detail from large sample areas using cryo-EM of frozen biological sample slices
This study explores how cryo-electron microscopy (cryo-EM) can be used to image large areas of frozen biological samples with near-atomic resolution. The researchers used a method called CEMOVIS, whic...
link.growkudos.com
July 2, 2025 at 10:26 AM
A plain language overview of our recent publication link.growkudos.com/1bt0psurksg
Out now at IUCJ doi.org/10.1107/S205...
June 25, 2025 at 7:36 AM
Out now at IUCJ doi.org/10.1107/S205...
Happy to announce our latest preprint. High resolution ribosomes in cells obtained on CEMOVIS (frozen-hydrated sections) www.biorxiv.org/content/10.1... in collaboration with @grigoriefflab.bsky.social and Wanda Kukulski.
April 1, 2025 at 6:18 AM
Happy to announce our latest preprint. High resolution ribosomes in cells obtained on CEMOVIS (frozen-hydrated sections) www.biorxiv.org/content/10.1... in collaboration with @grigoriefflab.bsky.social and Wanda Kukulski.
Reposted by Benoît Zuber
March 31, 2025 at 8:27 PM
Reposted by Benoît Zuber
Please check out our latest cryo-EM structure in the Journal of Structural Biology X: Structure of the PTS glucose transporter IICB stalled in an intermediate conformation.
www.sciencedirect.com/science/arti...
Congratulations Patrick for this great work !
www.sciencedirect.com/science/arti...
Congratulations Patrick for this great work !
Cryo-EM structure of a phosphotransferase system glucose transporter stalled in an intermediate conformation
The phosphotransferase system glucose-specific transporter IICBGlc serves as a central nutrient uptake system in bacteria. It transports glucose acros…
www.sciencedirect.com
March 19, 2025 at 6:46 PM
Please check out our latest cryo-EM structure in the Journal of Structural Biology X: Structure of the PTS glucose transporter IICB stalled in an intermediate conformation.
www.sciencedirect.com/science/arti...
Congratulations Patrick for this great work !
www.sciencedirect.com/science/arti...
Congratulations Patrick for this great work !
Reposted by Benoît Zuber
Great position for a postdoc to join @igreger.bsky.social’s group in the LMB’s Neurobiology Division, using diverse methods to study synaptic AMPA glutamate receptors.
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs
February 3, 2025 at 9:49 AM
Great position for a postdoc to join @igreger.bsky.social’s group in the LMB’s Neurobiology Division, using diverse methods to study synaptic AMPA glutamate receptors.
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs
Reposted by Benoît Zuber
Come and set up your own group at the @mrclmb.bsky.social in Cambridge, UK. Feel free to chat/email me with questions.
Join our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology!
You will be supported by core funding, excellent facilities & enthusiastic colleagues.
Apply by 18 MAR
www.nature.com/naturecareer...
You will be supported by core funding, excellent facilities & enthusiastic colleagues.
Apply by 18 MAR
www.nature.com/naturecareer...
February 3, 2025 at 7:51 PM
Come and set up your own group at the @mrclmb.bsky.social in Cambridge, UK. Feel free to chat/email me with questions.
Our latest JACS paper: high-resolution cryoEM of #aerolysin in lipid environment shows pore properties and 4 key constriction rings for #nanopore sensing. Collaboration with #DalPeraro & #Cao labs.
@coldpopeye.bsky.social
@unibern.bsky.social
#EPFL #UNIGE #DubochetCenter #MIC
shorturl.at/qyzbb
@coldpopeye.bsky.social
@unibern.bsky.social
#EPFL #UNIGE #DubochetCenter #MIC
shorturl.at/qyzbb
Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment
Aerolysin is a β-pore-forming toxin produced by most Aeromonas bacteria, which has attracted large attention in the field of nanopore sensing due to its narrow and charged pore lumen. Structurally sim...
shorturl.at
February 4, 2025 at 8:28 AM
Our latest JACS paper: high-resolution cryoEM of #aerolysin in lipid environment shows pore properties and 4 key constriction rings for #nanopore sensing. Collaboration with #DalPeraro & #Cao labs.
@coldpopeye.bsky.social
@unibern.bsky.social
#EPFL #UNIGE #DubochetCenter #MIC
shorturl.at/qyzbb
@coldpopeye.bsky.social
@unibern.bsky.social
#EPFL #UNIGE #DubochetCenter #MIC
shorturl.at/qyzbb
Reposted by Benoît Zuber
🎉Our latest publication "Predicting Polypharmacology with Web-Based Tools" by @maedehdarsaraee.bsky.social, Sacha Javor, and Jean-Louis Reymond is now published on Wiley!
Read it here👉
onlinelibrary.wiley.com/doi/abs/10.1...
#DCBP
#polypharmacology
#target_prediction
#chembl
#fingerprint
#ML
Read it here👉
onlinelibrary.wiley.com/doi/abs/10.1...
#DCBP
#polypharmacology
#target_prediction
#chembl
#fingerprint
#ML
January 6, 2025 at 8:58 AM
🎉Our latest publication "Predicting Polypharmacology with Web-Based Tools" by @maedehdarsaraee.bsky.social, Sacha Javor, and Jean-Louis Reymond is now published on Wiley!
Read it here👉
onlinelibrary.wiley.com/doi/abs/10.1...
#DCBP
#polypharmacology
#target_prediction
#chembl
#fingerprint
#ML
Read it here👉
onlinelibrary.wiley.com/doi/abs/10.1...
#DCBP
#polypharmacology
#target_prediction
#chembl
#fingerprint
#ML
Reposted by Benoît Zuber
Reminder:
Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative!
You will be supported by core funding, excellent facilities and a lively international community of researchers.
Apply by 19 Jan
www.nature.com/naturecareer...
Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative!
You will be supported by core funding, excellent facilities and a lively international community of researchers.
Apply by 19 Jan
www.nature.com/naturecareer...
January 6, 2025 at 3:31 PM
Reminder:
Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative!
You will be supported by core funding, excellent facilities and a lively international community of researchers.
Apply by 19 Jan
www.nature.com/naturecareer...
Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative!
You will be supported by core funding, excellent facilities and a lively international community of researchers.
Apply by 19 Jan
www.nature.com/naturecareer...
Reposted by Benoît Zuber
Our January cover shows a reconstructed synapse from a cryo-electron tomogram of cultured hippocampal neurons expressing a SNAP-25 mutant, using CryoVesNet developed by Amin Khosrozadeh, Benoît Zuber et al. (https://buff.ly/4h0DjGN).
JCB's January issue is here ✨ https://buff.ly/3ZZLqwE
JCB's January issue is here ✨ https://buff.ly/3ZZLqwE
January 6, 2025 at 3:02 PM
Our January cover shows a reconstructed synapse from a cryo-electron tomogram of cultured hippocampal neurons expressing a SNAP-25 mutant, using CryoVesNet developed by Amin Khosrozadeh, Benoît Zuber et al. (https://buff.ly/4h0DjGN).
JCB's January issue is here ✨ https://buff.ly/3ZZLqwE
JCB's January issue is here ✨ https://buff.ly/3ZZLqwE