Benjamin Basanta
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benjabsnt.bsky.social
Benjamin Basanta
@benjabsnt.bsky.social
100 followers 95 following 10 posts
Protein designer, cryoEMer, scientist at Arzeda. Views are my own. 🧉🇦🇷
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Reposted by Benjamin Basanta
nanigrotjahn.bsky.social
I have lots of opinions—but for your sake, I’ve limited them to segmentation in cryo-ET for this article 😉
www.sciencedirect.com/science/arti...

#teamtomo
Segmenting cryo-electron tomography data: Extracting models from cellular landscapes
Cryo-electron tomography provides an unprecedented view of cellular architecture, yet extracting meaningful biological insights remains challenging. S…
www.sciencedirect.com
July 11, 2025 at 12:46 AM
Reposted by Benjamin Basanta
nanigrotjahn.bsky.social
🚨New preprint!🚨 #teamtomo
We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles.

Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science
biorxivpreprint.bsky.social bioRxivpreprint @biorxivpreprint.bsky.social · May 1
Surface morphometrics reveals local membrane thickness variation in organellar subcompartments https://www.biorxiv.org/content/10.1101/2025.04.30.651574v1
May 1, 2025 at 7:42 PM
Reposted by Benjamin Basanta
natchembio.nature.com
A Perspective by @stephanieaw.bsky.social and @fraserlab.com discusses ways macromolecules use conformational entropy to control binding, catalysis, and allostery

www.nature.com/articles/s41...
Advances in uncovering the mechanisms of macromolecular conformational entropy - Nature Chemical Biology
Protein conformational entropy plays a vital role in functions like binding and catalysis. This Perspective discusses three ways macromolecules use conformational entropy: prepaying entropic costs, re...
www.nature.com
April 25, 2025 at 3:35 PM
Reposted by Benjamin Basanta
mgaldzic.bsky.social
Arzeda has been awarded DARPA funding to advance AI-driven protein design—even with limited data! We're pushing the boundaries to create next-gen proteins for national security, sustainability, and beyond. #AI #ProteinDesign
www.prnewswire.com/news-release...
Arzeda Awarded DARPA Funding to Advance AI-Driven Protein Design for National Security
/PRNewswire/ -- Arzeda, the industry-leading Protein Design Company™, today announced it has been selected for an award from the Defense Advanced Research...
www.prnewswire.com
January 25, 2025 at 3:41 AM
Reposted by Benjamin Basanta
baradlab.com
Tomorrow(!) morning at 9AM pacific, I am giving a webinar for EMS discussing the surface morphometrics pipeline and our approach to contextual structural biology #teamtomo. Free to attend, hope to see you all there!

us06web.zoom.us/webinar/regi...
Example series showing the surface morphometrics workflow
December 16, 2024 at 5:51 PM
Reposted by Benjamin Basanta
landerlab.bsky.social
The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex!

www.biorxiv.org/content/10.1...
November 14, 2024 at 3:19 PM
Reposted by Benjamin Basanta
hannahbaughman.bsky.social
Come be my colleague! UW Tacoma is hiring an Assistant Professor of Biochemistry. We're looking for someone excited about mentoring undergraduates in research, inclusive teaching, and being part of an interdisciplinary community of scholars. apply.interfolio.com/154390
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 21, 2024 at 12:04 AM
Reposted by Benjamin Basanta
baradlab.com
The Barad lab is hiring across all levels. Open positions here: baradlab.com/join/. If you are interested in doing cutting edge tomography and computational methods development to study intracellular bacterial infection, and living in Portland, OR, but don't fit the openings, reach out anyway!
Join the Barad Lab
The Barad Lab is a cryo-electron tomography and computational structural biology lab at Oregon Health & Science University
baradlab.com
January 24, 2024 at 5:45 PM
benjabsnt.bsky.social
I'm happy to share the publication of my postdoctoral work from the Lander lab at Scripps. We solved previously-unobserved conformations of human TTR, an 55kDa amyloid-forming protein, to great resolution.
www.biorxiv.org/content/10.1...
The conformational landscape of human transthyretin revealed by cryo-EM
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
January 24, 2024 at 5:57 AM
Reposted by Benjamin Basanta
baradlab.com
baradlab.com (aka tomo.science ) is now online! Beginning to feel like a real lab!
Barad Lab at OHSU
The Barad Lab is a cryo-electron tomography and computational structural biology lab at Oregon Health & Science University
baradlab.com
January 24, 2024 at 5:34 AM
Reposted by Benjamin Basanta
baradlab.com
The Barad lab is open!
Photo of my office with my nameplate on the wall
January 3, 2024 at 4:13 AM
Reposted by Benjamin Basanta
alexis-verger.cpesr.fr
Unusual repetitive DNA sequence in the E. coli genome --> CRISPR ---> genome editing

Ψ Pseudouridine ---> mRNA immunogenicity and potency ---> mRNA COVID vaccine

#basicresearch

Dear funders, dear governments

please increase the basic research budget !
October 2, 2023 at 1:52 PM