Béla Frohn
@belafrohn.bsky.social
PhD Student @ Schwille Lab, MPIB. Interested in the synthesis of protein design and synthetic cells. Eventually aiming to create life from scratch.
Reposted by Béla Frohn
With this, the last bit of my PhD at @embl.org is finally out!
We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models.
Paper: nature.com/articles/s42256-…
Code: github.com/mjendrusch/salad
Data: zenodo.org/records/14711580
1/🧵
We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models.
Paper: nature.com/articles/s42256-…
Code: github.com/mjendrusch/salad
Data: zenodo.org/records/14711580
1/🧵
‘Salad’ – a new AI model from EMBL scientists – offers major improvements in synthetic protein design.
Salad is significantly faster than comparable methods, and designing proteins that don't exist in nature can have applications in many scientific fields.
www.nature.com/articles/s42...
Salad is significantly faster than comparable methods, and designing proteins that don't exist in nature can have applications in many scientific fields.
www.nature.com/articles/s42...
September 24, 2025 at 12:27 PM
With this, the last bit of my PhD at @embl.org is finally out!
We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models.
Paper: nature.com/articles/s42256-…
Code: github.com/mjendrusch/salad
Data: zenodo.org/records/14711580
1/🧵
We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models.
Paper: nature.com/articles/s42256-…
Code: github.com/mjendrusch/salad
Data: zenodo.org/records/14711580
1/🧵
Reposted by Béla Frohn
Should researchers use proteins designed from scratch rather than those found in nature to build synthetic cells?
In a new review, Béla Frohn, Shunshi Kohyama and Petra Schwille explore how protein design and optimisation offer new possibilities for #syntheticcell design.
#syncell
In a new review, Béla Frohn, Shunshi Kohyama and Petra Schwille explore how protein design and optimisation offer new possibilities for #syntheticcell design.
#syncell
Can we build synthetic cells from de novo designed proteins?
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
May 22, 2025 at 7:11 AM
Should researchers use proteins designed from scratch rather than those found in nature to build synthetic cells?
In a new review, Béla Frohn, Shunshi Kohyama and Petra Schwille explore how protein design and optimisation offer new possibilities for #syntheticcell design.
#syncell
In a new review, Béla Frohn, Shunshi Kohyama and Petra Schwille explore how protein design and optimisation offer new possibilities for #syntheticcell design.
#syncell
Reposted by Béla Frohn
Can we build synthetic cells from de novo designed proteins?
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
May 21, 2025 at 8:35 AM
Can we build synthetic cells from de novo designed proteins?
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille.
❕Publication: doi.org/10.1038/s442...
#ProteinDesign #SyntheticBiology @belafrohn.bsky.social
Reposted by Béla Frohn
Protein design and optimization for synthetic cells
Protein design and optimization for synthetic cells
Nature Reviews Bioengineering, Published online: 19 May 2025; doi:10.1038/s44222-025-00318-1Bottom-up synthetic biology might greatly benefit from custom-made proteins as components of new biological systems. This Review discusses various protein optimization and design approaches, and explores how these can contribute to the generation of controllable synthetic cells.
www.nature.com
May 20, 2025 at 1:23 AM
Protein design and optimization for synthetic cells
New Review out!
Can we eventually design not only proteins, but entire cells from scratch? Check out the review I wrote in @natrevbioeng.nature.com about how to combine protein design with synthetic cell science.
Link: www.nature.com/articles/s44...
Can we eventually design not only proteins, but entire cells from scratch? Check out the review I wrote in @natrevbioeng.nature.com about how to combine protein design with synthetic cell science.
Link: www.nature.com/articles/s44...
May 20, 2025 at 2:15 PM
New Review out!
Can we eventually design not only proteins, but entire cells from scratch? Check out the review I wrote in @natrevbioeng.nature.com about how to combine protein design with synthetic cell science.
Link: www.nature.com/articles/s44...
Can we eventually design not only proteins, but entire cells from scratch? Check out the review I wrote in @natrevbioeng.nature.com about how to combine protein design with synthetic cell science.
Link: www.nature.com/articles/s44...