ayahabdel.bsky.social
@ayahabdel.bsky.social
Reposted
An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology
New in @natbiotech.nature.com: a team led by scientists at MSK and ‪University of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology
RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.
www.nature.com
July 29, 2025 at 1:41 AM
Reposted
Here for my first post. Our new approach to study tRNA aminoacylation by nanopore sequencing. Started as a napkin sketch ~1 year ago! This was a fun one, congrats to @laurakwhite.bsky.social and Aleks.

www.biorxiv.org/content/10.1...
Nanopore sequencing of intact aminoacylated tRNAs
Transfer RNAs (tRNA) are decorated during biogenesis with a variety of modifications that modulate their stability, aminoacylation, and decoding potential during translation. The complex landscape of ...
www.biorxiv.org
November 19, 2024 at 3:07 AM
Reposted
Here's the Six Classes of Molecular Interactions for designing drugs and their frequencies in protein-ligand complexes. They are all very useful in drug design (except perhaps the last one). I'll post a few slides from my Medchem Uni course for each interaction over the coming days/weeks.
November 19, 2024 at 11:46 AM