Apophenia
@apophenia.bsky.social
Psychiatrist; here for the vibes. Also TTRPGs.
Reposted by Apophenia
We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)
September 7, 2025 at 10:57 AM
We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)
Reposted by Apophenia
Anatomy of Moncrieff's Anti-Medication Playbook
A 3-step strategy of attacking medical psychiatry
www.psychiatrymargins.com/p/anatomy-of...
A 3-step strategy of attacking medical psychiatry
www.psychiatrymargins.com/p/anatomy-of...
Anatomy of Moncrieff's Anti-Medication Playbook
A 3-step strategy of attacking medical psychiatry
www.psychiatrymargins.com
February 8, 2025 at 2:22 PM
Anatomy of Moncrieff's Anti-Medication Playbook
A 3-step strategy of attacking medical psychiatry
www.psychiatrymargins.com/p/anatomy-of...
A 3-step strategy of attacking medical psychiatry
www.psychiatrymargins.com/p/anatomy-of...
Reposted by Apophenia
So misleading—as if there never had been a bio-psychosocial model. I have not read the book, but *no* plausible representation of depression in the brain will be incompatible the life-circumstance perspective. No biological theory ever proposed has been.
November 27, 2024 at 2:10 AM
So misleading—as if there never had been a bio-psychosocial model. I have not read the book, but *no* plausible representation of depression in the brain will be incompatible the life-circumstance perspective. No biological theory ever proposed has been.
Reposted by Apophenia
Odd, isn’t it, that Nietzsche was made much weaker, not stronger, by things that didn’t (immediately) kill him.
October 20, 2024 at 8:37 AM
Odd, isn’t it, that Nietzsche was made much weaker, not stronger, by things that didn’t (immediately) kill him.
Reposted by Apophenia
Systematic review & meta-analysis of severe adverse events (SAE) in psychedelic trials finds
(1) ~4% of people with mental health problems experience SAE
(2) true rates are possibly (much) higher because of a lack of systemic reporting in the literature.
🧪 #psychscisky #EpiSky
(1) ~4% of people with mental health problems experience SAE
(2) true rates are possibly (much) higher because of a lack of systemic reporting in the literature.
🧪 #psychscisky #EpiSky
Adverse Events in Studies of Classic Psychedelics
This systematic review and meta-analysis assesses the frequency and severity of adverse events (AEs), including serious and nonserious AEs, among studies
jamanetwork.com
September 6, 2024 at 8:32 AM
Systematic review & meta-analysis of severe adverse events (SAE) in psychedelic trials finds
(1) ~4% of people with mental health problems experience SAE
(2) true rates are possibly (much) higher because of a lack of systemic reporting in the literature.
🧪 #psychscisky #EpiSky
(1) ~4% of people with mental health problems experience SAE
(2) true rates are possibly (much) higher because of a lack of systemic reporting in the literature.
🧪 #psychscisky #EpiSky
Reposted by Apophenia
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific "Lab Leak" hypothesis.
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
On the day of Dr. Fauci's testimony, @nytimes.com decides to run a deeply unethical OpEd with snazzy graphics and snappy headlines about the Lab Leak.
The article itself contains multiple falsehoods and deep mischaracterizations.
Let's take every point in turn 👇🧵
www.nytimes.com/interactive/...
The article itself contains multiple falsehoods and deep mischaracterizations.
Let's take every point in turn 👇🧵
www.nytimes.com/interactive/...
Opinion | Why the Pandemic Probably Started in a Lab, in 5 Key Points
The world must not continue to bear the intolerable risks of research with the potential to cause pandemics.
www.nytimes.com
June 5, 2024 at 7:35 PM
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific "Lab Leak" hypothesis.
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin.
It's a prime example of conspiracism vs empiricism, so let's dive in.
🧵
Reposted by Apophenia
Counties in states that expanded Medicaid under the ACA saw a 25% decrease in drug arrests, a 19% drop in “violent offense” arrests, and a 24% decrease in “low-level” offense arrests (Simes & Jahn 2022). Expanding public benefits leads to lower crime rates!
November 20, 2023 at 12:37 PM
Counties in states that expanded Medicaid under the ACA saw a 25% decrease in drug arrests, a 19% drop in “violent offense” arrests, and a 24% decrease in “low-level” offense arrests (Simes & Jahn 2022). Expanding public benefits leads to lower crime rates!
Reposted by Apophenia
In depression screening, we often query for core symptoms sad mood & anhedonia, and "skip" the other 7 symptoms (e.g. sleep, appetite) if neither of the core symptoms are present.
What are the consequences of this practice?
Brief thread 🧵:
pubmed.ncbi.nlm.nih.gov/36972115/
What are the consequences of this practice?
Brief thread 🧵:
pubmed.ncbi.nlm.nih.gov/36972115/
Quantifying skip-out information loss when assessing major depression symptoms - PubMed
Large-scale mental health surveys screen participants for the presence of the core diagnostic criteria of a mental disorder such as major depressive disorder (MDD). Only participants who screen positi...
pubmed.ncbi.nlm.nih.gov
November 10, 2023 at 12:56 PM
In depression screening, we often query for core symptoms sad mood & anhedonia, and "skip" the other 7 symptoms (e.g. sleep, appetite) if neither of the core symptoms are present.
What are the consequences of this practice?
Brief thread 🧵:
pubmed.ncbi.nlm.nih.gov/36972115/
What are the consequences of this practice?
Brief thread 🧵:
pubmed.ncbi.nlm.nih.gov/36972115/
Reposted by Apophenia
1/12 New paper on psychedelics as treatments for mental health problems is out! We discuss 10 challenges which limit conclusions that can be drawn about safety/efficacy of psychedelic therapy.
We share a checklist for journalists, policymakers & others to assess quality of studies.
Brief thread:
We share a checklist for journalists, policymakers & others to assess quality of studies.
Brief thread:
History repeating: guidelines to address common problems in psychedelic science - Michiel van Elk, E...
Research in the last decade has expressed considerable optimism about the clinical potential of psychedelics for the treatment of mental disorders. This optimis...
journals.sagepub.com
November 6, 2023 at 2:01 PM
1/12 New paper on psychedelics as treatments for mental health problems is out! We discuss 10 challenges which limit conclusions that can be drawn about safety/efficacy of psychedelic therapy.
We share a checklist for journalists, policymakers & others to assess quality of studies.
Brief thread:
We share a checklist for journalists, policymakers & others to assess quality of studies.
Brief thread:
Reposted by Apophenia
Aesthetic literary experience may be conceived as the integration of cognitive and emotional events leading to transformative processes in the phenomenal aspect of conscious experience. This form of learning -conceptual and affective- may be helpful in creating...
November 4, 2023 at 3:42 PM
Aesthetic literary experience may be conceived as the integration of cognitive and emotional events leading to transformative processes in the phenomenal aspect of conscious experience. This form of learning -conceptual and affective- may be helpful in creating...
Reposted by Apophenia
Fascinating new study from @smfleming.bsky.social finds an illusion of overconfidence in AI decision making - humans judge artificial systems to be more confident and take their advice more readily.
psyarxiv.com/mjx2v/ #psyscisky 🧠🤖
psyarxiv.com/mjx2v/ #psyscisky 🧠🤖
psyarxiv.com
October 3, 2023 at 5:13 PM
Fascinating new study from @smfleming.bsky.social finds an illusion of overconfidence in AI decision making - humans judge artificial systems to be more confident and take their advice more readily.
psyarxiv.com/mjx2v/ #psyscisky 🧠🤖
psyarxiv.com/mjx2v/ #psyscisky 🧠🤖