Anke Sparmann
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ankesparmann.bsky.social
Anke Sparmann
@ankesparmann.bsky.social
64 followers 91 following 8 posts
Scientific writer @helmholtz-hiri.bsky.social and editor at Life Science Editors (https://www.lifescienceeditors.com/)
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Reposted by Anke Sparmann
natbiotech.nature.com
Inspired by bacteria’s defense strategies, scientists pioneer a novel method for genome editing #NBTintheNews via @helmholtzhzi.bsky.social www.helmholtz-hzi.de/en/media-cen...
September 22, 2025 at 6:44 PM
ankesparmann.bsky.social
2/2 @jorg-vogel-lab.bsky.social, @gerovac.bsky.social & team @helmholtz-hiri.bsky.social developed a non-genetic antisense oligomer approach to silence phage genes and probe their function—a powerful tool for functional genomics & phage therapy. Now out @nature.com go.nature.com/46b1XAQ
Cartoon depiction of the antisense oligomer approach to silence transcripts from phages in infected bacteria. In the top left, a bacteriophage infects a bacterial cells and injects its DNA, which is transcribed into an mRNA and expressed into a protein. In the top right, antisense oligomers (shown in red) delivered into the bacterium bind to the target phage mRNA and prevent synthesis of the phage protein. If the encoded protein is essential, phage replication and bacterial cell lysis (shown on the bottom right) are halted and the bacterium is protected, depicted by a red shield (bottom left).
September 12, 2025 at 12:56 PM
ankesparmann.bsky.social
Apparently hell keeps business hours :)
June 30, 2025 at 12:39 PM