Abdel Mazouzi
amazouzi.bsky.social
Abdel Mazouzi
@amazouzi.bsky.social
Scientist at the Netherlands Cancer Institute, EMBO fellow, Opinions are my own
Reposted by Abdel Mazouzi
Sarah Moser ( @sarahmoser.bsky.social) from the lab of Jos Jonkers, Netherlands Cancer Institute (@nkinl.bsky.social) & Oncode Institute (@oncodeinstitute.bsky.social). 👏🏾 5/
September 10, 2025 at 10:24 AM
Congrats Andre!
September 4, 2025 at 1:33 PM
Reposted by Abdel Mazouzi
This project has been a truly exciting chapter of my PhD journey and I am deeply grateful to everyone involved. A heartfelt thank you to my mentors, @josjonkers.bsky.social and @amazouzi.bsky.social for their guidance in solving the histone puzzle.
August 13, 2025 at 3:44 PM
Thank you for sharing!
August 14, 2025 at 12:55 PM
Here is the link to get the PDF of our paper in case you don’t have access to Nature: rdcu.be/eAChv
NASP modulates histone turnover to drive PARP inhibitor resistance
Nature - PARP inhibitor treatment triggers histone release from the chromatin in cancer cells; consequently, targeting the histone chaperone NASP renders cells vulnerable to PARP inhibition.
rdcu.be
August 13, 2025 at 5:10 PM
Thanks Sabrina!
August 13, 2025 at 5:07 PM
Thanks Andre!
August 13, 2025 at 5:07 PM