Antoni Martija
@amartija.bsky.social
Postdoctoral scholar in the Bhaduri Lab at UCLA
Reposted by Antoni Martija
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
biorxiv.org
June 24, 2025 at 2:24 AM
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
💥Now on
@biorxivpreprint
: biorxiv.org/content/10.1...
Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab
Reposted by Antoni Martija
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
May 6, 2025 at 4:50 PM
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote the generation of upper layer cortical neurons through NRXN1-mediated contacts with outer radial glia. www.biorxiv.org/content/10.1...
Reposted by Antoni Martija
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks that can describe mechanisms of cortical development, centering on peak stages of neurogenesis 🧠🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex - Nature Neuroscience
Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing these programs in...
www.nature.com
May 2, 2025 at 12:39 AM
It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)
Reposted by Antoni Martija
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
www.biorxiv.org
March 13, 2025 at 4:36 AM
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...