Ali Amara
amara-lab.bsky.social
Ali Amara
@amara-lab.bsky.social
Reposted by Ali Amara
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 6:05 PM
Reposted by Ali Amara
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 17, 2025 at 6:43 PM
Reposted by Ali Amara
#NotOnlyParasites! 2 Cell papers by @edchuong.bsky.social lab & Amigorena lab demonstrate that transposable elements #TEs can exonize giving rise to functional (often shorter) proteins with distinct functions: eg a decoy short IFNAR2 that inhibits #interferon signaling! www.cell.com/cell/fulltex...
Transposable element exonization generates a reservoir of evolving and functional protein isoforms
Transposable element exonization by unannotated splicing events produces stable protein isoforms with acquired functions that are subject to evolutionary selection.
www.cell.com
December 12, 2024 at 5:36 PM
Reposted by Ali Amara
Thinking of colleagues in Argentina. Sad to read this.

www.nature.com/articles/d41...
‘There will be nothing left’: researchers fear collapse of science in Argentina
One year into President Javier Milei’s presidency, scientists are exiting the country in the face of big budget cuts.
www.nature.com
December 10, 2024 at 11:38 AM
Reposted by Ali Amara
Working on Negative Strand RNA viruses? Here is the THE meeting you don't want to miss in 2025: #NSV2025!
It will take place in vibrant Montpellier, South of France, and is organized by Wendy Barclay, Paul Duprex, Sean Whelan and Olivier Moncorgé

Please share widely! #ViroSky #LoveVirology
December 9, 2024 at 10:05 AM
Reposted by Ali Amara
Faster and more accurate protein modeling with CryFold. By focusing on nearby points (Local Attention) and employing map masking, CryFold excels in generating models from challenging maps regions. It enables a more cost-efficient model building. 🧵
💾 github.com/SBQ-1999/Cry...
November 25, 2024 at 5:25 PM
Reposted by Ali Amara
Excited by viruses and how our bodies repel them? A fully funded PhD project now available combining expertise from the lab to the clinic. #virology #immunology #dermatology #CRISPR #vector-vertebrate biology. Help us spread the word. ☺️

www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Can skin inflammation stop mosquito-borne virus infection? at University of York on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Can skin inflammation stop mosquito-borne virus infection? at University of York, listed on FindAPhD.com
www.findaphd.com
November 8, 2024 at 9:13 AM