Aging and Metabolism
@am-omrf.bsky.social
The Aging and Metabolism Research Program at Oklahoma Medical Research Foundation
https://omrf.org/programs/aging-metabolism-research-program/
https://omrf.org/programs/aging-metabolism-research-program/
Pinned
Aging and Metabolism
@am-omrf.bsky.social
· Nov 23
Check it out ⤵️
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
From our own Dr. Benjamin Miller's Edward F. Adolph Distinguished Lecture- Protein and energy metabolism: a state of flux @benjaminfmiller.bsky.social journals.physiology.org/doi/full/10....
Edward F. Adolph Distinguished Lecture. Protein and energy metabolism: a state of flux | Journal of Applied Physiology | American Physiological Society
Physiology processes are integrated, dynamic, and periodic and thus benefit from methods that capture their dynamic nature. Since we are often limited to discrete sampling points in physiological stud...
journals.physiology.org
October 29, 2025 at 3:48 PM
From our own Dr. Benjamin Miller's Edward F. Adolph Distinguished Lecture- Protein and energy metabolism: a state of flux @benjaminfmiller.bsky.social journals.physiology.org/doi/full/10....
Why do some people get massive gains from exercise while others see little change? 🤔
The M^3AX Trial is diving into the "Inter-individual Response Heterogeneity" to figure out how to maximize adaptations to exercise, especially as we age. journals.physiology.org/doi/abs/10.1...
The M^3AX Trial is diving into the "Inter-individual Response Heterogeneity" to figure out how to maximize adaptations to exercise, especially as we age. journals.physiology.org/doi/abs/10.1...
Multidimensional Modeling to Maximize Adaptations to eXercise: The M3AX Trial Rationale and Study Design | Journal of Applied Physiology | American Physiological Society
Age-related functional declines are thought to be caused by hallmark biological processes that manifest in physical, mental, and metabolic impairments compromising intrinsic capacity, healthspan and q...
journals.physiology.org
October 27, 2025 at 7:16 PM
Why do some people get massive gains from exercise while others see little change? 🤔
The M^3AX Trial is diving into the "Inter-individual Response Heterogeneity" to figure out how to maximize adaptations to exercise, especially as we age. journals.physiology.org/doi/abs/10.1...
The M^3AX Trial is diving into the "Inter-individual Response Heterogeneity" to figure out how to maximize adaptations to exercise, especially as we age. journals.physiology.org/doi/abs/10.1...
Huge congratulations to our very own Dr. Benjamin Miller on his induction into the prestigious Academy for Health and Lifespan Research! 🎉 His groundbreaking work is at the forefront of extending human healthspan. @omrf.bsky.social
omrf.org/2025/05/19/o...
omrf.org/2025/05/19/o...
OMRF scientist named to international research academy
Benjamin Miller, Ph.D., inducted into the Academy for Health and Lifespan Research
omrf.org
May 21, 2025 at 5:24 PM
Huge congratulations to our very own Dr. Benjamin Miller on his induction into the prestigious Academy for Health and Lifespan Research! 🎉 His groundbreaking work is at the forefront of extending human healthspan. @omrf.bsky.social
omrf.org/2025/05/19/o...
omrf.org/2025/05/19/o...
Reposted by Aging and Metabolism
With a new three-year grant from the American Heart Association, OMRF's Dr. Kamil Kobak will study a common and life-threatening heart condition. 🫀
Read more: omrf.org/2025/05/15/o...
Read more: omrf.org/2025/05/15/o...
May 16, 2025 at 3:42 PM
With a new three-year grant from the American Heart Association, OMRF's Dr. Kamil Kobak will study a common and life-threatening heart condition. 🫀
Read more: omrf.org/2025/05/15/o...
Read more: omrf.org/2025/05/15/o...
Reposted by Aging and Metabolism
U.S. Rep. Stephanie Bice highlighted OMRF at a congressional budget hearing yesterday involving the U.S. Department of Health and Human Services, which includes the National Institutes of Health.
We thank you for sharing the vital impact and importance of biomedical research.
We thank you for sharing the vital impact and importance of biomedical research.
May 15, 2025 at 3:53 PM
U.S. Rep. Stephanie Bice highlighted OMRF at a congressional budget hearing yesterday involving the U.S. Department of Health and Human Services, which includes the National Institutes of Health.
We thank you for sharing the vital impact and importance of biomedical research.
We thank you for sharing the vital impact and importance of biomedical research.
Reposted by Aging and Metabolism
Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...
2025 Study section tracking
docs.google.com
February 24, 2025 at 4:17 PM
Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...
Reposted by Aging and Metabolism
Grateful for the award! A major thanks to the Multiplexing Protein Analysis Core and folks at @am-omrf.bsky.social (like @benjaminfmiller.bsky.social) who were instrumental in gathering preliminary data for our NIH grant proposal.
We are so glad to highlight 2023 Oklahoma NSC Pilot Awardee Robert Musci! Check out the full Pilot Awardee Spotlight here: bit.ly/40Obn3A #AgingResearch @oknathanshock.bsky.social
January 28, 2025 at 1:51 AM
Grateful for the award! A major thanks to the Multiplexing Protein Analysis Core and folks at @am-omrf.bsky.social (like @benjaminfmiller.bsky.social) who were instrumental in gathering preliminary data for our NIH grant proposal.
Recent paper from the Stout lab reveals Canagliflozin, a diabetes drug, may delay ovarian aging by preserving follicular reserves and improving mitochondrial function. Could this hold promise for delaying menopause and systemic aging in women? 🧬
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice - GeroScience
Ovarian aging is characterized by declines in follicular reserve and the emergence of mitochondrial dysfunction, reactive oxygen species production, inflammation, and fibrosis, which eventually result...
link.springer.com
January 10, 2025 at 5:44 PM
Recent paper from the Stout lab reveals Canagliflozin, a diabetes drug, may delay ovarian aging by preserving follicular reserves and improving mitochondrial function. Could this hold promise for delaying menopause and systemic aging in women? 🧬
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Exciting progress in ALS research from the Van Remmen lab! This study demonstrates that the nitrone compound OKN-007 delays motor neuron loss and slows disease progression in a mouse model of amyotrophic lateral sclerosis.
www.frontiersin.org/journals/neu...
www.frontiersin.org/journals/neu...
Frontiers | The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis
www.frontiersin.org
December 29, 2024 at 7:48 PM
Exciting progress in ALS research from the Van Remmen lab! This study demonstrates that the nitrone compound OKN-007 delays motor neuron loss and slows disease progression in a mouse model of amyotrophic lateral sclerosis.
www.frontiersin.org/journals/neu...
www.frontiersin.org/journals/neu...
Reposted by Aging and Metabolism
First post on Bluesky! Congrats to Aga Borowik and Miller Lab on this thoughtful and thought provoking piece “The expanding roles of myonuclei in adult skeletal muscle health and function” portlandpress.com/biochemsoctr... @myoblue.bsky.social @am-omrf.bsky.social @omrf.bsky.social
The expanding roles of myonuclei in adult skeletal muscle health and function
Skeletal muscle cells (myofibers) require multiple nuclei to support a cytoplasmic volume that is larger than other mononuclear cell types. It is dogmatic that mammalian resident myonuclei rely on ste...
portlandpress.com
December 21, 2024 at 1:37 PM
First post on Bluesky! Congrats to Aga Borowik and Miller Lab on this thoughtful and thought provoking piece “The expanding roles of myonuclei in adult skeletal muscle health and function” portlandpress.com/biochemsoctr... @myoblue.bsky.social @am-omrf.bsky.social @omrf.bsky.social
Reposted by Aging and Metabolism
I visited the Oklahoma Medical Research Foundation (OMRF) today. Incredible place! Thank you Magdalena Bieniasz for the invitation. Great to meet with Joan Walker, Doris Bennrook, Bethany Hannafon, Maureen Cox, Xin Zhang, and Priyabrata Mukherjee. @omrf.bsky.social @am-omrf.bsky.social
December 20, 2024 at 5:43 AM
I visited the Oklahoma Medical Research Foundation (OMRF) today. Incredible place! Thank you Magdalena Bieniasz for the invitation. Great to meet with Joan Walker, Doris Bennrook, Bethany Hannafon, Maureen Cox, Xin Zhang, and Priyabrata Mukherjee. @omrf.bsky.social @am-omrf.bsky.social
Congratulations, Weronika! It’s well deserved!
I’m thrilled to share this incredible news as the year comes to a close! I’m deeply grateful to @americanheart.bsky.social for funding my Predoctoral Fellowship. Many thanks to my mentor @annchiao.bsky.social for her guidance and support! @am-omrf.bsky.social
December 16, 2024 at 2:18 PM
Congratulations, Weronika! It’s well deserved!
A new review from the Van Remmen lab. Everything you wanted to know about ROS and oxidative stress in muscle ⤵️
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reactive oxygen species in skeletal muscle injury, fatigue, regeneration and ageing: In memory of John Faulkner
One of the most critical factors impacting healthspan in the elderly is the loss of muscle mass and function, clinically referred to as sarcopenia. Mu…
www.sciencedirect.com
December 2, 2024 at 5:02 PM
A new review from the Van Remmen lab. Everything you wanted to know about ROS and oxidative stress in muscle ⤵️
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Aging and Metabolism
We are all going to Alaska!! #AGE2025 as organized by the indomitable Ben Miller at OMRF @benjaminfmiller.bsky.social @americanaging.bsky.social @am-omrf.bsky.social
We're happy to join all of you here on Bluesky! Be sure to give us a follow and check out our site for new announcements and opportunities in research on aging biology!
www.americanagingassociation.org
www.americanagingassociation.org
Home
www.americanagingassociation.org
November 26, 2024 at 7:11 PM
We are all going to Alaska!! #AGE2025 as organized by the indomitable Ben Miller at OMRF @benjaminfmiller.bsky.social @americanaging.bsky.social @am-omrf.bsky.social
Check it out ⤵️
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
November 23, 2024 at 6:29 PM
Check it out ⤵️
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
Several of our scientists and outstanding trainees are on Bluesky.
go.bsky.app/5oUbpNy
How cool is this?? OMRF has its own scientific relic, located in the heart of the Aging and Metabolism Program.
November 22, 2024 at 2:48 PM
How cool is this?? OMRF has its own scientific relic, located in the heart of the Aging and Metabolism Program.
Welcome to all our new followers and thanks to @brunetlab.bsky.social for adding us to the Aging Research starter pack!
November 22, 2024 at 1:47 PM
Welcome to all our new followers and thanks to @brunetlab.bsky.social for adding us to the Aging Research starter pack!
Reposted by Aging and Metabolism
November 22, 2024 at 4:23 AM
Congratulations to Dr. Wan Hee Yoon! For those not familiar, BSF brings together American and Israeli scientists and researchers for innovative partnerships that enhance the advancement of scientific breakthroughs.
November 19, 2024 at 9:00 PM
Congratulations to Dr. Wan Hee Yoon! For those not familiar, BSF brings together American and Israeli scientists and researchers for innovative partnerships that enhance the advancement of scientific breakthroughs.
Where did we get our profile picture? The foyer at OMRF has an amazing artistic cell representation with inlaid marble #mitochondria
November 18, 2024 at 11:29 PM
Where did we get our profile picture? The foyer at OMRF has an amazing artistic cell representation with inlaid marble #mitochondria
New research in Nature Communications shows how SK channel dysfunction makes dopamine neurons hyperexcitable in a mouse model of Alzheimer's. Could this be a key to understanding cognitive decline? 🤔 #Alzheimers #Neuroscience #Dopamine
@mikebeckstead.bsky.social
www.nature.com/articles/s41...
@mikebeckstead.bsky.social
www.nature.com/articles/s41...
VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction - Nature Communications
Recent studies unexpectedly indicate involvement of ventral tegmental area dopamine neurons in Alzheimer’s disease (AD). Here, the authors identified the enzyme casein kinase 2 as a mechanistic link b...
www.nature.com
November 18, 2024 at 10:57 PM
New research in Nature Communications shows how SK channel dysfunction makes dopamine neurons hyperexcitable in a mouse model of Alzheimer's. Could this be a key to understanding cognitive decline? 🤔 #Alzheimers #Neuroscience #Dopamine
@mikebeckstead.bsky.social
www.nature.com/articles/s41...
@mikebeckstead.bsky.social
www.nature.com/articles/s41...
How’s this for a first post?
New publication in Nature Communications about the role of dopamine in Alzheimer’s disease⤵️
omrf.org/2024/11/12/o...
New publication in Nature Communications about the role of dopamine in Alzheimer’s disease⤵️
omrf.org/2024/11/12/o...
OMRF discovers new chemical link to Alzheimer’s
Findings may explain mood changes that precede disease
omrf.org
November 15, 2024 at 4:53 AM
How’s this for a first post?
New publication in Nature Communications about the role of dopamine in Alzheimer’s disease⤵️
omrf.org/2024/11/12/o...
New publication in Nature Communications about the role of dopamine in Alzheimer’s disease⤵️
omrf.org/2024/11/12/o...