Alison Low
@alow.bsky.social
Post-doctoral scientist at Roslin Institute, University of Edinburgh. Microbiology, E. coli, phage, UTI, O157:H7
Not long to go until the abstract deadline for #Microbio26 and we have a dedicated #phage session with a couple of super invited speakers - don’t miss it phage enthusiasts!
There's still time to submit your abstract to Annual Conference 2026. Abstract submission closes at 23:59 GMT on 11 November 2025. For the full list of abstract submissions we welcome, visit our events page: microb.io/AC26Abstracts #Microbio26
October 30, 2025 at 9:36 AM
Not long to go until the abstract deadline for #Microbio26 and we have a dedicated #phage session with a couple of super invited speakers - don’t miss it phage enthusiasts!
Really super talk from @nicholden.bsky.social this morning exploring all things E. coli #microbio25. Lovely to consider the big picture of our favourite bug!
April 3, 2025 at 10:11 AM
Really super talk from @nicholden.bsky.social this morning exploring all things E. coli #microbio25. Lovely to consider the big picture of our favourite bug!
Lovely poster by Emily from our group - a side project investigating the use of ClearColi for phage production
April 2, 2025 at 4:40 PM
Lovely poster by Emily from our group - a side project investigating the use of ClearColi for phage production
@strain9000.bsky.social group travel to VoM UK. Looking forward to listening to all things phage
January 23, 2025 at 10:17 AM
@strain9000.bsky.social group travel to VoM UK. Looking forward to listening to all things phage
And we have a second competition funded PhD studentship available - get in touch if you want to study #phage in beautiful Edinburgh. www.findaphd.com/phds/project...
December 19, 2024 at 6:49 AM
And we have a second competition funded PhD studentship available - get in touch if you want to study #phage in beautiful Edinburgh. www.findaphd.com/phds/project...
Reposted by Alison Low
New paper from the group. Very proud to share our recent work for the first time here on Bluesky- give me 50 likes and it’s a permanent move!🤣.
doi.org/10.1098/rsob...
doi.org/10.1098/rsob...
November 29, 2024 at 9:15 PM
New paper from the group. Very proud to share our recent work for the first time here on Bluesky- give me 50 likes and it’s a permanent move!🤣.
doi.org/10.1098/rsob...
doi.org/10.1098/rsob...
Reposted by Alison Low
New MRC-funded postdoc with me on comparative bacterial genomics/phylodynamics @roslininstitute.bsky.social university of Edinburgh. Great multidisciplinary team and collaboration with partners at Shanghai Jao Tong University.
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
PDRA in Bacterial Genomics
We are looking for a Post-Doctoral Research Associate in Bacterial Genomics at the Laboratory for Bacterial Evolution and Pathogenesis (www.ed.ac.uk/roslin/research/divisions/bacteriology/lbep) at The...
elxw.fa.em3.oraclecloud.com
December 4, 2024 at 9:56 AM
New MRC-funded postdoc with me on comparative bacterial genomics/phylodynamics @roslininstitute.bsky.social university of Edinburgh. Great multidisciplinary team and collaboration with partners at Shanghai Jao Tong University.
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Interested in a EastBio PhD studentship developing phage therapy to treat pathogenic E coli infections in farm animals then apply below to come and work with us at The Roslin Instute, University of Edinburgh www.findaphd.com/phds/project...
EASTBIO: Prediction of capsule type to improve efficacy of phage cocktails for eradication of multi-drug resistant Escherichia coli from the gastrointestinal tract of colonised livestock species at Un...
PhD Project - EASTBIO: Prediction of capsule type to improve efficacy of phage cocktails for eradication of multi-drug resistant Escherichia coli from the gastrointestinal tract of colonised livestock...
www.findaphd.com
November 29, 2024 at 5:38 PM
Interested in a EastBio PhD studentship developing phage therapy to treat pathogenic E coli infections in farm animals then apply below to come and work with us at The Roslin Instute, University of Edinburgh www.findaphd.com/phds/project...
Reposted by Alison Low
Bacteriophages evolve enhanced persistence to a mucosal surface.
DOI: 10.1073/pnas.2116197119
https://pubmed.ncbi.nlm.nih.gov/35767643/
DOI: 10.1073/pnas.2116197119
https://pubmed.ncbi.nlm.nih.gov/35767643/
Bacteriophages evolve enhanced persistence to a mucosal surface - PubMed
The majority of viruses within the gut are obligate bacterial viruses known as bacteriophages (phages). Their bacteriotropism underscores the study of phage ecology in the gut, where they modulate and coevolve with gut bacterial communities. Traditionally, these ecological and evolutionary questions …
pubmed.ncbi.nlm.nih.gov
November 29, 2024 at 2:37 AM
Bacteriophages evolve enhanced persistence to a mucosal surface.
DOI: 10.1073/pnas.2116197119
https://pubmed.ncbi.nlm.nih.gov/35767643/
DOI: 10.1073/pnas.2116197119
https://pubmed.ncbi.nlm.nih.gov/35767643/
Reposted by Alison Low
How invasive are different E .coli capsules and how many are there? Find out here and use the group 2 and 3 database to type your own!
medrxiv.org/cgi/content/...
medrxiv.org/cgi/content/...
Group 2 and 3 ABC-transporter dependant capsular K-loci contribute significantly to variation in the invasive potential of Escherichia coli
The major opportunistic pathogen Escherichia coli is the largest cause of antimicrobial resistance (AMR) associated infections and deaths globally. Considerable antigenic diversity has been documented...
medrxiv.org
November 27, 2024 at 2:44 AM
How invasive are different E .coli capsules and how many are there? Find out here and use the group 2 and 3 database to type your own!
medrxiv.org/cgi/content/...
medrxiv.org/cgi/content/...
Reposted by Alison Low
We've long been able to find new phages and figure out what they interact with. But what about the other direction: if you have a gene, like an antibiotic resistance efflux pump, or a phage defense system, and you want to find phages that do or do not interact with it?
Now you can!
Now you can!
What if we dug into a sample a little more “wild” and a little less characterized? We combined our strains with a wastewater sample (thank you citizens of Boston for your ~contributions~), and again we found fluorescent hits! Each was isolated and characteristics confirmed on monoculture lawns. 5/
November 23, 2024 at 6:49 PM
We've long been able to find new phages and figure out what they interact with. But what about the other direction: if you have a gene, like an antibiotic resistance efflux pump, or a phage defense system, and you want to find phages that do or do not interact with it?
Now you can!
Now you can!
@uoe-eid.bsky.social Winter lecture Alison Holmes giving a very timely talk for #WAAW ‘Protecting healthcare, preventing infections and preserving antibiotics’
November 20, 2024 at 5:50 PM
@uoe-eid.bsky.social Winter lecture Alison Holmes giving a very timely talk for #WAAW ‘Protecting healthcare, preventing infections and preserving antibiotics’
Starting the year off with a week in the sunshine. Beautiful view from the apartment to Mount Teide, Tenerife. Some good work news already this year so hoping 2024 will be a great one for our group!
January 3, 2024 at 9:18 AM
Starting the year off with a week in the sunshine. Beautiful view from the apartment to Mount Teide, Tenerife. Some good work news already this year so hoping 2024 will be a great one for our group!
New pre-print: study from our group addressing one of the hurdles of phage therapy - rapidly selecting the right phage cocktail to treat an infection - using bacterial genome sequence to predict effective phage cocktail design biorxiv.org/content/10.110…
November 25, 2023 at 2:39 PM
New pre-print: study from our group addressing one of the hurdles of phage therapy - rapidly selecting the right phage cocktail to treat an infection - using bacterial genome sequence to predict effective phage cocktail design biorxiv.org/content/10.110…
Reposted by Alison Low
Check out the latest Microbiology Primer on using TraDIS to link genotype to phenotype www.microbiologyresearch.org/content/micr...
November 1, 2023 at 12:57 PM
Check out the latest Microbiology Primer on using TraDIS to link genotype to phenotype www.microbiologyresearch.org/content/micr...
A fantastic PdD opportunity at The Roslin Institute studying phage In aquaculture. #phage #UniversityOfEdinburgh www.findaphd.com/phds/project...
EASTBIO: Can phage therapy be used in aquaculture to tackle bacterial infections and AMR? at Univer...
PhD Project - EASTBIO: Can phage therapy be used in aquaculture to tackle bacterial infections and AMR? at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
October 16, 2023 at 8:05 AM
A fantastic PdD opportunity at The Roslin Institute studying phage In aquaculture. #phage #UniversityOfEdinburgh www.findaphd.com/phds/project...