DefinitelyNotAlice
@alicele.bsky.social
Evolutionary scientists, curious epidemiologist, plasmid enthusiast, old school social!
Sardinian, Italian and European in the Uk.
Briton in training, loves BCN.
Mum. Baker. Birdwatcher. Gardener.
Very opinionated & opinions are my own.
Sardinian, Italian and European in the Uk.
Briton in training, loves BCN.
Mum. Baker. Birdwatcher. Gardener.
Very opinionated & opinions are my own.
Reposted by DefinitelyNotAlice
Reposted by DefinitelyNotAlice
PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification. #PathogenSurveillance #Nextflow #Bioinformatics #WGS #PathogenIdentification @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 9, 2025 at 5:49 PM
PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification. #PathogenSurveillance #Nextflow #Bioinformatics #WGS #PathogenIdentification @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by DefinitelyNotAlice
November 9, 2025 at 11:56 AM
Reposted by DefinitelyNotAlice
Eurasian Wren (Troglodytes troglodytes) perched in the reed bed #birds #ukwildlife #birdlovers #birdfaves #birdphotos
November 9, 2025 at 11:47 AM
Eurasian Wren (Troglodytes troglodytes) perched in the reed bed #birds #ukwildlife #birdlovers #birdfaves #birdphotos
One of the things that amazes me after all this time in the UK is that I see the different shades of grey sky...
In Sardinia there is only grey and blue.
Here there is dark grey, light grey, shiny grey, foggy grey, not-that-bad grey, cloudy grey, grey where you can see shadows of blue...
In Sardinia there is only grey and blue.
Here there is dark grey, light grey, shiny grey, foggy grey, not-that-bad grey, cloudy grey, grey where you can see shadows of blue...
November 9, 2025 at 11:54 AM
One of the things that amazes me after all this time in the UK is that I see the different shades of grey sky...
In Sardinia there is only grey and blue.
Here there is dark grey, light grey, shiny grey, foggy grey, not-that-bad grey, cloudy grey, grey where you can see shadows of blue...
In Sardinia there is only grey and blue.
Here there is dark grey, light grey, shiny grey, foggy grey, not-that-bad grey, cloudy grey, grey where you can see shadows of blue...
This is interesting and sounds to me much more realistic than many other accounts...
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Remembering my sister Rosalind Franklin
Rosalind Franklin died of ovarian cancer in 1958 aged 37 years. Sympathy and feminism
have combined to give us her familiar image as a downtrodden woman scientist, brilliant
but neglected, a heroine t...
www.thelancet.com
November 9, 2025 at 10:48 AM
This is interesting and sounds to me much more realistic than many other accounts...
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by DefinitelyNotAlice
I almost missed the 5th anniversary of the greatest moment in political history.
Happy Four Seasons Total Landscaping Day!
Happy Four Seasons Total Landscaping Day!
November 7, 2025 at 8:33 PM
I almost missed the 5th anniversary of the greatest moment in political history.
Happy Four Seasons Total Landscaping Day!
Happy Four Seasons Total Landscaping Day!
Halloween ✔️
Guy Fawkes ✔️ ... Well, still ongoing!
Let the Christmas Season begin!!!
(Daughter and friends decorating, me drinking mulled cider with mums)
Guy Fawkes ✔️ ... Well, still ongoing!
Let the Christmas Season begin!!!
(Daughter and friends decorating, me drinking mulled cider with mums)
November 7, 2025 at 7:14 PM
Halloween ✔️
Guy Fawkes ✔️ ... Well, still ongoing!
Let the Christmas Season begin!!!
(Daughter and friends decorating, me drinking mulled cider with mums)
Guy Fawkes ✔️ ... Well, still ongoing!
Let the Christmas Season begin!!!
(Daughter and friends decorating, me drinking mulled cider with mums)
Reposted by DefinitelyNotAlice
#ISMEJournal paper from Simon Heilbronner
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
academic.oup.com/ismej/advanc...
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
academic.oup.com/ismej/advanc...
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
Abstract. The human nasal microbiome can serve as a reservoir for pathogens. In particular, the opportunistic pathogen Staphylococcus aureus can be a membe
academic.oup.com
November 6, 2025 at 8:38 AM
#ISMEJournal paper from Simon Heilbronner
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
academic.oup.com/ismej/advanc...
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
academic.oup.com/ismej/advanc...
Reposted by DefinitelyNotAlice
"New York will remain a city of immigrants, a city built by immigrants, powered by immigrants, and as of tonight, led by an immigrant."
In the richest city, in the richest country in the world, on a platform of Democratic Socialism. 👏🏽
In the richest city, in the richest country in the world, on a platform of Democratic Socialism. 👏🏽
November 5, 2025 at 8:03 AM
"New York will remain a city of immigrants, a city built by immigrants, powered by immigrants, and as of tonight, led by an immigrant."
In the richest city, in the richest country in the world, on a platform of Democratic Socialism. 👏🏽
In the richest city, in the richest country in the world, on a platform of Democratic Socialism. 👏🏽
I would love to study the evolution of food in time and space...
And this article confirms
A. That genoise and pan di spagna are one and the same
B. That in pan di spagna there is no yeast, the rising comes from the eggs
elpais.com/gastronomia/...
And this article confirms
A. That genoise and pan di spagna are one and the same
B. That in pan di spagna there is no yeast, the rising comes from the eggs
elpais.com/gastronomia/...
Por qué en Italia se llama “pan de España” al bizcocho
Tras ser expulsados de España, los judíos se repartieron por todo el Mediterráneo. Algunos fueron a Génova, llevando consigo su bizcocho de almidón de trigo
elpais.com
November 5, 2025 at 9:11 AM
I would love to study the evolution of food in time and space...
And this article confirms
A. That genoise and pan di spagna are one and the same
B. That in pan di spagna there is no yeast, the rising comes from the eggs
elpais.com/gastronomia/...
And this article confirms
A. That genoise and pan di spagna are one and the same
B. That in pan di spagna there is no yeast, the rising comes from the eggs
elpais.com/gastronomia/...
Reposted by DefinitelyNotAlice
Two papers accepted and Liverpool beat Real Madrid - am I dreaming? This week is delivering
November 4, 2025 at 10:14 PM
Two papers accepted and Liverpool beat Real Madrid - am I dreaming? This week is delivering
Reposted by DefinitelyNotAlice
Microbial genomics for antimicrobial resistance ecology and action www.nature.com/articles/s41... 🧬🖥️🧪🦠 rdcu.be/eOcFc
November 4, 2025 at 5:04 PM
Microbial genomics for antimicrobial resistance ecology and action www.nature.com/articles/s41... 🧬🖥️🧪🦠 rdcu.be/eOcFc
Reposted by DefinitelyNotAlice
"For older people whose brains have begun to show molecular signs of the disease, but who have yet to display any cognitive symptoms, taking as few as 3,000 to 5,000 steps per day can help to stave off mental decline, a study finds1." www.nature.com/articles/d41...
Alzheimer’s decline slows with just a few thousand steps a day
A modest increase in physical activity can delay cognitive decline by three years — or more.
www.nature.com
November 4, 2025 at 2:56 AM
"For older people whose brains have begun to show molecular signs of the disease, but who have yet to display any cognitive symptoms, taking as few as 3,000 to 5,000 steps per day can help to stave off mental decline, a study finds1." www.nature.com/articles/d41...
One never ceases to learn!
New word learned today:
Despondent
Meaning: in low spirits from loss of hope or courage (see gif).
More depressed and flat than despair...
Just in case you needed it!
New word learned today:
Despondent
Meaning: in low spirits from loss of hope or courage (see gif).
More depressed and flat than despair...
Just in case you needed it!
a woman is laying on a couch with a box of chocolates in her hand .
Alt: a woman is laying on a couch with a box of chocolates in her hand looking sad and a little disjevelled
media.tenor.com
November 3, 2025 at 1:49 PM
One never ceases to learn!
New word learned today:
Despondent
Meaning: in low spirits from loss of hope or courage (see gif).
More depressed and flat than despair...
Just in case you needed it!
New word learned today:
Despondent
Meaning: in low spirits from loss of hope or courage (see gif).
More depressed and flat than despair...
Just in case you needed it!
Reposted by DefinitelyNotAlice
Rare Diseases Masked by Common Diagnoses: Genome Sequencing Uncovers Hidden Variants Impacting Treatment Outcomes
by Rahimov F, Jacobs BM (...) Smaoui N et 12 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2405459
by Rahimov F, Jacobs BM (...) Smaoui N et 12 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2405459
November 1, 2025 at 12:52 PM
Rare Diseases Masked by Common Diagnoses: Genome Sequencing Uncovers Hidden Variants Impacting Treatment Outcomes
by Rahimov F, Jacobs BM (...) Smaoui N et 12 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2405459
by Rahimov F, Jacobs BM (...) Smaoui N et 12 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2405459
Reposted by DefinitelyNotAlice
Detecting Introgression in Shallow Phylogenies: How Minor Molecular Clock Deviations Lead to Major Inference Errors academic.oup.com/mbe/article/...
Detecting Introgression in Shallow Phylogenies: How Minor Molecular Clock Deviations Lead to Major Inference Errors
Abstract. Recent theoretical and algorithmic advances in introgression detection, coupled with the growing availability of genome-scale data, have highligh
academic.oup.com
November 1, 2025 at 4:32 PM
Detecting Introgression in Shallow Phylogenies: How Minor Molecular Clock Deviations Lead to Major Inference Errors academic.oup.com/mbe/article/...
Reposted by DefinitelyNotAlice
2024-2025 Covid-19 vaccine cut risks of emergency visits, hospitalizations, and deaths among U.S. veterans, showing significant protective effects.
by Cai M, Xie Y and Al-Aly Z in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2510226
by Cai M, Xie Y and Al-Aly Z in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2510226
November 1, 2025 at 8:28 PM
2024-2025 Covid-19 vaccine cut risks of emergency visits, hospitalizations, and deaths among U.S. veterans, showing significant protective effects.
by Cai M, Xie Y and Al-Aly Z in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2510226
by Cai M, Xie Y and Al-Aly Z in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2510226
Reposted by DefinitelyNotAlice
Our new paper:
Science for Pandemic Preparedness: A precautionary framework
dx.doi.org/10.1111/jep....
Science for Pandemic Preparedness: A precautionary framework
dx.doi.org/10.1111/jep....
Science for Pandemic Preparedness: A Precautionary Framework
In the early weeks of the pandemic year 2020, health agencies were slow to warn of the potential for a global health emergency while scientists waited for ‘sufficient’ evidence of human-to-human tran...
dx.doi.org
November 2, 2025 at 2:39 PM
Our new paper:
Science for Pandemic Preparedness: A precautionary framework
dx.doi.org/10.1111/jep....
Science for Pandemic Preparedness: A precautionary framework
dx.doi.org/10.1111/jep....
Reposted by DefinitelyNotAlice
PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification www.biorxiv.org/content/10.1...
Code: github.com/nf-core/path...
Nextflow nf-core pipeline: nf-co.re/pathogensurv...
Code: github.com/nf-core/path...
Nextflow nf-core pipeline: nf-co.re/pathogensurv...
November 2, 2025 at 9:58 PM
PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification www.biorxiv.org/content/10.1...
Code: github.com/nf-core/path...
Nextflow nf-core pipeline: nf-co.re/pathogensurv...
Code: github.com/nf-core/path...
Nextflow nf-core pipeline: nf-co.re/pathogensurv...
Reposted by DefinitelyNotAlice
Increasingly seeing a strange false logic in political discourse around science, which goes something like:
1. No observational evidence can be trusted
2. The only reliable evidence is an RCT
3. RCTs involving pharma can't be trusted
4. Public funds shouldn't cover RCTs, so pharma must do them
1. No observational evidence can be trusted
2. The only reliable evidence is an RCT
3. RCTs involving pharma can't be trusted
4. Public funds shouldn't cover RCTs, so pharma must do them
November 2, 2025 at 2:58 PM
Increasingly seeing a strange false logic in political discourse around science, which goes something like:
1. No observational evidence can be trusted
2. The only reliable evidence is an RCT
3. RCTs involving pharma can't be trusted
4. Public funds shouldn't cover RCTs, so pharma must do them
1. No observational evidence can be trusted
2. The only reliable evidence is an RCT
3. RCTs involving pharma can't be trusted
4. Public funds shouldn't cover RCTs, so pharma must do them
Does anyone want to organize a discussion on this article (academia edition)?
I am having a lot of feelings about it!
www.theguardian.com/money/2025/n...
I am having a lot of feelings about it!
www.theguardian.com/money/2025/n...
Even when unthinkable things were happening to me, my first instinct was to work. Am I addicted?
It was only years later, when I heard the word workaholic being used seriously for the first time, that I wondered whether I had a problem
www.theguardian.com
November 1, 2025 at 4:27 PM
Does anyone want to organize a discussion on this article (academia edition)?
I am having a lot of feelings about it!
www.theguardian.com/money/2025/n...
I am having a lot of feelings about it!
www.theguardian.com/money/2025/n...
As I was dressing up the young lady of the house as a black cat yesterday night, I remembered that there is a technical reason why black cats are believed to bring bad luck: because horses did not see them until they were too close, got scared and bolted the carriage... (Not fact checked)
Yes, Halloween is the deadliest day of the year for child pedestrians—great advice from @mcbazacophd.bsky.social
(It’s also our kid’s birthday)
(It’s also our kid’s birthday)
November 1, 2025 at 9:46 AM
As I was dressing up the young lady of the house as a black cat yesterday night, I remembered that there is a technical reason why black cats are believed to bring bad luck: because horses did not see them until they were too close, got scared and bolted the carriage... (Not fact checked)