Ali Akbari
aliakbari.bsky.social
Ali Akbari
@aliakbari.bsky.social
Research Associate at Reich lab @HarvardMed and @HarvardHEB
For neutrophil count, J-PEP expands interpretation beyond immune cells, highlighting hepatic-inflammatory and neuroimmune axes.
May 13, 2025 at 8:38 PM
For hypertension (HTN), it identifies stromal and adrenal-endocrine processes missed by prior methods.
May 13, 2025 at 8:38 PM
For type 2 diabetes (T2D), J-PEP refines known pathways like β-cell dysfunction and uncovers underexplored immune and developmental signals.
May 13, 2025 at 8:38 PM
Reposted by Ali Akbari
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
academic.oup.com/mbe/advance-...
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
Abstract. A recently proposed model suggests a severe bottleneck in the panmictic ancestral population of modern humans during the Early to Middle Pleistoc
academic.oup.com
February 17, 2025 at 4:56 PM
Reposted by Ali Akbari
Distinct explanations underlie gene-environment interactions in the UK Biobank.
www.cell.com/ajhg/abstrac...
Distinct explanations underlie gene-environment interactions in the UK Biobank
The role of gene-environment (GxE) interaction in disease and complex trait architectures is widely hypothesized but currently unknown. Here, we apply three statistical approaches to quantify and dist...
www.cell.com
February 17, 2025 at 4:56 PM