Ali Rifat
@ali-rifat.bsky.social
MD and neuroscientist @ChariteBerlin | interested in microglial physiology
Microglia are the brain’s most dynamic cells, constantly extending and retracting their processes to monitor the parenchyma and respond to potential danger with inflammatory signaling.
Our new study in @ScienceAdvances @science.org explores how these functions are regulated.
Our new study in @ScienceAdvances @science.org explores how these functions are regulated.
October 25, 2025 at 3:24 PM
Microglia are the brain’s most dynamic cells, constantly extending and retracting their processes to monitor the parenchyma and respond to potential danger with inflammatory signaling.
Our new study in @ScienceAdvances @science.org explores how these functions are regulated.
Our new study in @ScienceAdvances @science.org explores how these functions are regulated.
Reposted by Ali Rifat
Very interesting paper in Science Advances by the Madry lab showing that the chloride channel Clic1 regulates morphodynamics and surveillance of #microglia via ERM proteins. These functions are chloride independent. www.science.org/doi/10.1126/...
The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation
CLIC1 regulates surveillance, morphology, and interleukin release in mouse and human brain microglia.
www.science.org
October 22, 2025 at 7:37 PM
Very interesting paper in Science Advances by the Madry lab showing that the chloride channel Clic1 regulates morphodynamics and surveillance of #microglia via ERM proteins. These functions are chloride independent. www.science.org/doi/10.1126/...