Alex Fratzl 🇪🇺
@alex-fratzl.bsky.social
🇪🇺 European Neuroscientist
👁🧠🎓 @IOB (PD) | @SWC (PhD) | @EPFL (BSc/MSc)
🕊️🗳️📖 Peace | Democracy | Education
🌐 https://www.linkedin.com/in/alexfratzl
👁🧠🎓 @IOB (PD) | @SWC (PhD) | @EPFL (BSc/MSc)
🕊️🗳️📖 Peace | Democracy | Education
🌐 https://www.linkedin.com/in/alexfratzl
Reposted by Alex Fratzl 🇪🇺
🚨 CALL FOR APPLICATIONS 🚨
Looking for your next academic step?
Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases.
⏰ Deadline: November 16, 2025 (midnight CET)
🔗 iob.ch/phd-md-phd-program
#IOB #Basel #PhDProgram #VisionScience
Looking for your next academic step?
Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases.
⏰ Deadline: November 16, 2025 (midnight CET)
🔗 iob.ch/phd-md-phd-program
#IOB #Basel #PhDProgram #VisionScience
iob.ch
September 30, 2025 at 11:06 AM
🚨 CALL FOR APPLICATIONS 🚨
Looking for your next academic step?
Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases.
⏰ Deadline: November 16, 2025 (midnight CET)
🔗 iob.ch/phd-md-phd-program
#IOB #Basel #PhDProgram #VisionScience
Looking for your next academic step?
Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases.
⏰ Deadline: November 16, 2025 (midnight CET)
🔗 iob.ch/phd-md-phd-program
#IOB #Basel #PhDProgram #VisionScience
Reposted by Alex Fratzl 🇪🇺
Applications are now open for the SWC Systems Neuroscience PhD Programme.
Join us in London!
🧠 World-class neuroscience training
💰 Fully-funded 4-year programme
🖥️ Close links to @gatsbyucl.bsky.social
Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
Join us in London!
🧠 World-class neuroscience training
💰 Fully-funded 4-year programme
🖥️ Close links to @gatsbyucl.bsky.social
Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
September 23, 2025 at 8:47 AM
Applications are now open for the SWC Systems Neuroscience PhD Programme.
Join us in London!
🧠 World-class neuroscience training
💰 Fully-funded 4-year programme
🖥️ Close links to @gatsbyucl.bsky.social
Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
Join us in London!
🧠 World-class neuroscience training
💰 Fully-funded 4-year programme
🖥️ Close links to @gatsbyucl.bsky.social
Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
Reposted by Alex Fratzl 🇪🇺
Single-cell electroporation is performed via patch pipette and under 2-photon visual guidance in vivo. A short voltage pulse train is applied through the pipette to deliver RNA molecules into a targeted cell. The video below shows this process in cortical neurons expressing GCaMP6s.
September 15, 2025 at 9:19 AM
Single-cell electroporation is performed via patch pipette and under 2-photon visual guidance in vivo. A short voltage pulse train is applied through the pipette to deliver RNA molecules into a targeted cell. The video below shows this process in cortical neurons expressing GCaMP6s.
Reposted by Alex Fratzl 🇪🇺
Gene editing of single, targeted neurons in vivo is now feasible. We are proud to present our preprint for highly efficient single-cell electroporation using RNA. With @alex-fratzl.bsky.social, @munzlab.bsky.social, Botond Roska @iobswiss.bsky.social
#neuroskyence
www.biorxiv.org/content/10.1...
#neuroskyence
www.biorxiv.org/content/10.1...
In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance
The balance between excitatory and inhibitory neurotransmission is fundamental for normal brain function, yet the adaptation of individual neurons to disrupted excitatory-inhibitory balance is not wel...
www.biorxiv.org
September 15, 2025 at 9:19 AM
Gene editing of single, targeted neurons in vivo is now feasible. We are proud to present our preprint for highly efficient single-cell electroporation using RNA. With @alex-fratzl.bsky.social, @munzlab.bsky.social, Botond Roska @iobswiss.bsky.social
#neuroskyence
www.biorxiv.org/content/10.1...
#neuroskyence
www.biorxiv.org/content/10.1...
Reposted by Alex Fratzl 🇪🇺
In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance https://www.biorxiv.org/content/10.1101/2025.09.13.672380v1
September 14, 2025 at 7:15 AM
In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance https://www.biorxiv.org/content/10.1101/2025.09.13.672380v1
Reposted by Alex Fratzl 🇪🇺
🧠👁️ How does your eye prevent seeing a scrambled world? @anbucci.bsky.social and @ffranke.bsky.social reveal the eye's secret "clockwork": bigger axons = faster signals = perfect visual timing!
📖 Full paper nature.com/articles/s41593-025-02011-3
#Vision #AcademicSky #Neuroscience #Retina
Image ©IOB
📖 Full paper nature.com/articles/s41593-025-02011-3
#Vision #AcademicSky #Neuroscience #Retina
Image ©IOB
August 13, 2025 at 10:53 AM
🧠👁️ How does your eye prevent seeing a scrambled world? @anbucci.bsky.social and @ffranke.bsky.social reveal the eye's secret "clockwork": bigger axons = faster signals = perfect visual timing!
📖 Full paper nature.com/articles/s41593-025-02011-3
#Vision #AcademicSky #Neuroscience #Retina
Image ©IOB
📖 Full paper nature.com/articles/s41593-025-02011-3
#Vision #AcademicSky #Neuroscience #Retina
Image ©IOB
Reposted by Alex Fratzl 🇪🇺
🔬 Thrilled to share that our latest research on how the retina synchronizes visual signals has been featured by Medical Xpress! 🧠👁️
It’s exciting to see our work reaching a broader audience. Huge thanks to Medical Xpress for highlighting it!
#neuroskyence #retina #VisualProcessing
It’s exciting to see our work reaching a broader audience. Huge thanks to Medical Xpress for highlighting it!
#neuroskyence #retina #VisualProcessing
August 8, 2025 at 2:33 PM
🔬 Thrilled to share that our latest research on how the retina synchronizes visual signals has been featured by Medical Xpress! 🧠👁️
It’s exciting to see our work reaching a broader audience. Huge thanks to Medical Xpress for highlighting it!
#neuroskyence #retina #VisualProcessing
It’s exciting to see our work reaching a broader audience. Huge thanks to Medical Xpress for highlighting it!
#neuroskyence #retina #VisualProcessing
Reposted by Alex Fratzl 🇪🇺
Finally it's out! www.nature.com/articles/s41... How flexible are essential innate behaviours and their underlying neural circuits? @felixbaier.bsky.social & I, with Hopi Hoekstra and @farrowlab.bsky.social, addressed this by studying the #evolution of threat avoidance in Peromyscus mice.
The neural basis of species-specific defensive behaviour in Peromyscus mice - Nature
Visual threat triggers contrasting freeze and escape defensive responses in two species of deer mice as a result of different activation thresholds downstream of the superior colliculus in the do...
www.nature.com
July 23, 2025 at 4:57 PM
Finally it's out! www.nature.com/articles/s41... How flexible are essential innate behaviours and their underlying neural circuits? @felixbaier.bsky.social & I, with Hopi Hoekstra and @farrowlab.bsky.social, addressed this by studying the #evolution of threat avoidance in Peromyscus mice.
Reposted by Alex Fratzl 🇪🇺
1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits
Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...
www.biorxiv.org
July 21, 2025 at 7:58 AM
1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Alex Fratzl 🇪🇺
🚨🚨Job Alert🚨🚨!! Neuroscience, Physiology and Pharmacology are recruiting a new lecturer/associate professor! an amazing opportunity to join our fantastic dept! @ucl.ac.uk @ucllifesciences.bsky.social @uclnpp.bsky.social post here:
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Lecturer / Associate Professor - London, England job with University College London (UCL) | 12840324
About usThe Division of Biosciences at UCL is one of the world's foremost centres for research and teaching in the biological sciences. We have an out
www.nature.com
June 19, 2025 at 12:59 PM
🚨🚨Job Alert🚨🚨!! Neuroscience, Physiology and Pharmacology are recruiting a new lecturer/associate professor! an amazing opportunity to join our fantastic dept! @ucl.ac.uk @ucllifesciences.bsky.social @uclnpp.bsky.social post here:
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Alex Fratzl 🇪🇺
My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date
Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour.
Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org
Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour.
Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org
April 17, 2025 at 9:28 PM
My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date
Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour.
Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org
Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour.
Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org
Reposted by Alex Fratzl 🇪🇺
Hi, We have new open positions – PhD student and postdocs– experimental or computational– in our research groups at @nerflabs.bsky.social in Leuven Belgium on neural circuit basis of visual behavior/developmental disorders. I am at Cosyne Workshops and happy to discuss opportunities.
March 31, 2025 at 2:50 AM
Hi, We have new open positions – PhD student and postdocs– experimental or computational– in our research groups at @nerflabs.bsky.social in Leuven Belgium on neural circuit basis of visual behavior/developmental disorders. I am at Cosyne Workshops and happy to discuss opportunities.
Reposted by Alex Fratzl 🇪🇺
📢 🚨 Postdoc Opportunity 📢 🚨
Join us at @lmumuenchen.bsky.social to study how neural circuits 🧠 drive adaptive behavior. The lab uses state-of-the-art neuroscience technologies and offers a supportive environment 🤗!
⏳ Deadline: 15. April 2025
Learn more and apply: www.fens.org/careers/job-...
Join us at @lmumuenchen.bsky.social to study how neural circuits 🧠 drive adaptive behavior. The lab uses state-of-the-art neuroscience technologies and offers a supportive environment 🤗!
⏳ Deadline: 15. April 2025
Learn more and apply: www.fens.org/careers/job-...
March 13, 2025 at 6:20 AM
📢 🚨 Postdoc Opportunity 📢 🚨
Join us at @lmumuenchen.bsky.social to study how neural circuits 🧠 drive adaptive behavior. The lab uses state-of-the-art neuroscience technologies and offers a supportive environment 🤗!
⏳ Deadline: 15. April 2025
Learn more and apply: www.fens.org/careers/job-...
Join us at @lmumuenchen.bsky.social to study how neural circuits 🧠 drive adaptive behavior. The lab uses state-of-the-art neuroscience technologies and offers a supportive environment 🤗!
⏳ Deadline: 15. April 2025
Learn more and apply: www.fens.org/careers/job-...
It is my great pleasure to share this paper from my postdoc in which we developed an implantable biohybrid neural interface toward synaptic deep brain stimulation. Great collaboration with @tobiasruff.bsky.social and team at ETH!
We are thrilled to have contributed to this innovative research published in Advanced Functional Materials, together with the team of @tobiasruff.bsky.social at ETH!
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
February 20, 2025 at 3:52 PM
It is my great pleasure to share this paper from my postdoc in which we developed an implantable biohybrid neural interface toward synaptic deep brain stimulation. Great collaboration with @tobiasruff.bsky.social and team at ETH!
Reposted by Alex Fratzl 🇪🇺
We are thrilled to have contributed to this innovative research published in Advanced Functional Materials, together with the team of @tobiasruff.bsky.social at ETH!
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
February 20, 2025 at 3:06 PM
We are thrilled to have contributed to this innovative research published in Advanced Functional Materials, together with the team of @tobiasruff.bsky.social at ETH!
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
Check out the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...
🧠 #neuroscience #brainresearch #academicsky
Reposted by Alex Fratzl 🇪🇺
Exciting news! My PhD work with @flor-iacaruso.bsky.social is now online as a preprint!
We explored how the timing between visual and auditory stimuli shapes multisensory interactions. Check it out!
We explored how the timing between visual and auditory stimuli shapes multisensory interactions. Check it out!
Functional specialisation of multisensory temporal integration in the mouse superior colliculus https://www.biorxiv.org/content/10.1101/2025.02.11.637674v1
February 12, 2025 at 5:40 PM
Exciting news! My PhD work with @flor-iacaruso.bsky.social is now online as a preprint!
We explored how the timing between visual and auditory stimuli shapes multisensory interactions. Check it out!
We explored how the timing between visual and auditory stimuli shapes multisensory interactions. Check it out!
Reposted by Alex Fratzl 🇪🇺
How do different sensory signals combine in the computation of cognitive maps? I’m thrilled to share our new preprint, in which we investigate this question in the context of the head-direction system:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Joint visual-vestibular computation of head direction and reflexive eye movement
Several cognitive maps have been identified, but what sensory signals drive them and how these are combined are not well understood. One such map, the head-direction representation, is believed to be ...
www.biorxiv.org
February 12, 2025 at 6:42 AM
How do different sensory signals combine in the computation of cognitive maps? I’m thrilled to share our new preprint, in which we investigate this question in the context of the head-direction system:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Alex Fratzl 🇪🇺
I am very happy to share that our big collaborative effort on developing "An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation" has now been published in Advanced Functional Materials! #neuroscience, #academicsky
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
February 11, 2025 at 3:27 PM
I am very happy to share that our big collaborative effort on developing "An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation" has now been published in Advanced Functional Materials! #neuroscience, #academicsky
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Alex Fratzl 🇪🇺
A thalamic hub-and-spoke network enables visual perception during action by coordinating visuomotor dynamics 🧪🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A thalamic hub-and-spoke network enables visual perception during action by coordinating visuomotor dynamics - Nature Neuroscience
Animals must distinguish between signals from sensory stimuli and action-generated signals. This paper shows that the ventral lateral geniculate nucleus acts as a corollary discharge center to suppres...
www.nature.com
February 10, 2025 at 1:21 PM
A thalamic hub-and-spoke network enables visual perception during action by coordinating visuomotor dynamics 🧪🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Alex Fratzl 🇪🇺
Another step on Moldova's path to the EU.
We have signed a 2-year Strategy for Energy Independence and Resilience of Moldova.
It will bring Moldova into our energy system, reduce its reliance on insecure Russian supplies and help lower energy costs for all Moldovans ↓
europa.eu/!nqG7Dd
We have signed a 2-year Strategy for Energy Independence and Resilience of Moldova.
It will bring Moldova into our energy system, reduce its reliance on insecure Russian supplies and help lower energy costs for all Moldovans ↓
europa.eu/!nqG7Dd
February 4, 2025 at 10:16 AM
Another step on Moldova's path to the EU.
We have signed a 2-year Strategy for Energy Independence and Resilience of Moldova.
It will bring Moldova into our energy system, reduce its reliance on insecure Russian supplies and help lower energy costs for all Moldovans ↓
europa.eu/!nqG7Dd
We have signed a 2-year Strategy for Energy Independence and Resilience of Moldova.
It will bring Moldova into our energy system, reduce its reliance on insecure Russian supplies and help lower energy costs for all Moldovans ↓
europa.eu/!nqG7Dd
Reposted by Alex Fratzl 🇪🇺
I’m thrilled to share our preprint presenting MORSE: a new way to simultaneously & quantitatively track patterns of neuromodulators/neuropeptides in vitro & in vivo using spatially multiplexed 3D imaging of 10+ green optical sensors on a microendoscope
biorxiv.org/content/10.1101/2025.01.26.634931v1
biorxiv.org/content/10.1101/2025.01.26.634931v1
January 27, 2025 at 12:50 PM
I’m thrilled to share our preprint presenting MORSE: a new way to simultaneously & quantitatively track patterns of neuromodulators/neuropeptides in vitro & in vivo using spatially multiplexed 3D imaging of 10+ green optical sensors on a microendoscope
biorxiv.org/content/10.1101/2025.01.26.634931v1
biorxiv.org/content/10.1101/2025.01.26.634931v1
Reposted by Alex Fratzl 🇪🇺
RA positions with potential PhD continuation are now open! We're seeking two candidates with slice patch clamp or programming skills for the projects outlined in the advert: www.jobs.cam.ac.uk/job/50040/
Apply by 21 February!
Apply by 21 February!
📣 Opportunity Alert! We have two PhD positions in our lab at Cambridge University starting in Autumn 2025. Exceptional candidates may join earlier as RAs and receive PhD funding if scholarship applications are unsuccessful (RA advert coming soon!).
Details here: www.keshavarzilab.com/blog/phd-pos...
Details here: www.keshavarzilab.com/blog/phd-pos...
January 26, 2025 at 1:37 PM
RA positions with potential PhD continuation are now open! We're seeking two candidates with slice patch clamp or programming skills for the projects outlined in the advert: www.jobs.cam.ac.uk/job/50040/
Apply by 21 February!
Apply by 21 February!
Reposted by Alex Fratzl 🇪🇺
Our vision for energy? Clean, affordable, and proudly made in Europe.
By investing in next-gen clean energy like fusion and geothermal, we are ensuring a sustainable future for all Europeans.
Our success over the past two years is clear. And the third quarter of 2024 proves it ↓
By investing in next-gen clean energy like fusion and geothermal, we are ensuring a sustainable future for all Europeans.
Our success over the past two years is clear. And the third quarter of 2024 proves it ↓
January 23, 2025 at 8:15 AM
Our vision for energy? Clean, affordable, and proudly made in Europe.
By investing in next-gen clean energy like fusion and geothermal, we are ensuring a sustainable future for all Europeans.
Our success over the past two years is clear. And the third quarter of 2024 proves it ↓
By investing in next-gen clean energy like fusion and geothermal, we are ensuring a sustainable future for all Europeans.
Our success over the past two years is clear. And the third quarter of 2024 proves it ↓
Reposted by Alex Fratzl 🇪🇺
Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro
Apply by: February 16th!
Apply by: February 16th!
January 14, 2025 at 4:58 AM
Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro
Apply by: February 16th!
Apply by: February 16th!
Reposted by Alex Fratzl 🇪🇺
We are pleased to share that RhyGaze, IOB's first spin-off, has secured Series A funding with an USD 86 million investment to advance vision restoration therapy.
Read more: iob.ch/news-view-al...
#Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub
Read more: iob.ch/news-view-al...
#Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub
January 10, 2025 at 2:26 PM
We are pleased to share that RhyGaze, IOB's first spin-off, has secured Series A funding with an USD 86 million investment to advance vision restoration therapy.
Read more: iob.ch/news-view-al...
#Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub
Read more: iob.ch/news-view-al...
#Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub