Anne Nichols
@aecnichols.bsky.social
Tendon cell biology, mechanobiology, and epitenon-obsessed.
Assistant Professor 👩🏻🔬
@nichols_lab / @ROC_CMSR / @URMC
Assistant Professor 👩🏻🔬
@nichols_lab / @ROC_CMSR / @URMC
Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.
July 1, 2025 at 6:01 PM
Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.
It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.
July 1, 2025 at 6:01 PM
It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.
Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.
July 1, 2025 at 6:01 PM
Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.
Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.
July 1, 2025 at 5:54 PM
Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.
It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.
July 1, 2025 at 5:54 PM
It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.
Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.
July 1, 2025 at 5:54 PM
Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.
Is this the universe telling us that we're on the right track with our mouse model of tendon healing??? 🤯 #teamtendon
January 15, 2025 at 6:10 PM
Is this the universe telling us that we're on the right track with our mouse model of tendon healing??? 🤯 #teamtendon
I'm not sure what I expected 😂 #teamtendon
December 3, 2024 at 8:30 PM
I'm not sure what I expected 😂 #teamtendon
catch ya'll on the flip side...
November 25, 2024 at 4:35 PM
catch ya'll on the flip side...
AMAZING talk by @ccstorytime to a packed house at #ORS2024!! Awesome to learn about TENDOTIME- can't wait to hear results! #teamtendon @ors_tendon
November 25, 2024 at 4:35 PM
AMAZING talk by @ccstorytime to a packed house at #ORS2024!! Awesome to learn about TENDOTIME- can't wait to hear results! #teamtendon @ors_tendon
Heading to the airport for #ORS2024! Excited to see everyone and hear about all the cool science people have been up to! Also excited to share #HITSteamtendon work! Thanks to @easa_me for the graphic 😎
November 25, 2024 at 4:35 PM
Heading to the airport for #ORS2024! Excited to see everyone and hear about all the cool science people have been up to! Also excited to share #HITSteamtendon work! Thanks to @easa_me for the graphic 😎
Great NIRA talk by @JasonCMarvin to a packed house!! Congrats Jason- have loved watching this project come together over the years! #teamtendon
November 25, 2024 at 4:35 PM
Great NIRA talk by @JasonCMarvin to a packed house!! Congrats Jason- have loved watching this project come together over the years! #teamtendon
Ever wonder what kind of cells are in mature human scar? So did we! Come find me during this morning's poster session (Poster 728) to find out how we used scRNA-seq to explore!! #teamtendon #ORS2023
November 25, 2024 at 4:35 PM
Ever wonder what kind of cells are in mature human scar? So did we! Come find me during this morning's poster session (Poster 728) to find out how we used scRNA-seq to explore!! #teamtendon #ORS2023
Excited to share our newest @biorxivpreprint!
"Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury"
@LoiselleLab @ROC_CMSR #teamtendon
A very quick 🧵:
tinyurl.com/2p8h3e93
"Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury"
@LoiselleLab @ROC_CMSR #teamtendon
A very quick 🧵:
tinyurl.com/2p8h3e93
November 25, 2024 at 4:35 PM
Excited to share our newest @biorxivpreprint!
"Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury"
@LoiselleLab @ROC_CMSR #teamtendon
A very quick 🧵:
tinyurl.com/2p8h3e93
"Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury"
@LoiselleLab @ROC_CMSR #teamtendon
A very quick 🧵:
tinyurl.com/2p8h3e93
14-years-ago-me being so excited about a confocal image of an adipocyte that I posted it on facebook = adorable 😂😂
November 25, 2024 at 4:35 PM
14-years-ago-me being so excited about a confocal image of an adipocyte that I posted it on facebook = adorable 😂😂
Here it is, straight from the man himself!!!🙌🙌🙌 Great story that shows how dogma gets established and how hard it is to overturn. Also now I have a citation to support why I will never doing a trilineage assay.
loom.ly/2c-e_-E
loom.ly/2c-e_-E
November 25, 2024 at 4:35 PM
Here it is, straight from the man himself!!!🙌🙌🙌 Great story that shows how dogma gets established and how hard it is to overturn. Also now I have a citation to support why I will never doing a trilineage assay.
loom.ly/2c-e_-E
loom.ly/2c-e_-E
Look who finally arrived today... exactly a year from the day that I submitted the proposal! Thanks @NIH_NIAMS for the support- super excited to get cracking on this project!! 💪💪 #teamtendon #teamepitenon @ROC_CMSR @URochester_SMD
November 25, 2024 at 4:35 PM
Look who finally arrived today... exactly a year from the day that I submitted the proposal! Thanks @NIH_NIAMS for the support- super excited to get cracking on this project!! 💪💪 #teamtendon #teamepitenon @ROC_CMSR @URochester_SMD
Best birthday and lab ever!! a whole feast from @easa_me and cheesecake from @LoiselleLab?? can I get older everyday please 🤩
November 25, 2024 at 4:34 PM
Best birthday and lab ever!! a whole feast from @easa_me and cheesecake from @LoiselleLab?? can I get older everyday please 🤩
November 25, 2024 at 4:34 PM
Not sure I was quite ready for the 50 degree temperature difference, but it's good to be home! Had a great time at #ORS2022- awesome to see/meet everyone and hear about all the amazing science! Here's to #ORS2023!!🍻
November 25, 2024 at 4:34 PM
Not sure I was quite ready for the 50 degree temperature difference, but it's good to be home! Had a great time at #ORS2022- awesome to see/meet everyone and hear about all the amazing science! Here's to #ORS2023!!🍻
Even audio difficulties couldn't stop @AntonionKorcari from giving an amazing talk! Great job Tony!! 💪💪
@LoiselleLab #teamtendon
@LoiselleLab #teamtendon
November 25, 2024 at 4:34 PM
Even audio difficulties couldn't stop @AntonionKorcari from giving an amazing talk! Great job Tony!! 💪💪
@LoiselleLab #teamtendon
@LoiselleLab #teamtendon
Heading to #ORS2022? Check out the @LoiselleLab #teamtendon lineup! (1/n)
November 25, 2024 at 4:34 PM
Heading to #ORS2022? Check out the @LoiselleLab #teamtendon lineup! (1/n)