Adrià Sogues
@adriasogues.bsky.social
Spores, Bacterial S-layers, Cell Envelope & Cell Division. Structural Microbiologist 💎❄️🔬 at Institut Pasteur (Paris). Formerly at VIB-VUB in Brussels (EMBO & MSCA fellow) 🇫🇷🇧🇪🇪🇸
A new chapter begins! Happy to be back at the @pasteur.fr , a place that feels like home. Excited for the journey ahead and all the science to come!
September 18, 2025 at 8:52 AM
A new chapter begins! Happy to be back at the @pasteur.fr , a place that feels like home. Excited for the journey ahead and all the science to come!
3/4🧵How does the S-layer grow during cell division? Using pulse-chase labeling with the SpyTag-SpyCatcher system, we discovered that new S-layer is inserted exclusively at the cell poles, exactly where peptidoglycan synthesis occurs. S-layer assembly and growth are tightly coordinated!
July 30, 2025 at 4:56 AM
3/4🧵How does the S-layer grow during cell division? Using pulse-chase labeling with the SpyTag-SpyCatcher system, we discovered that new S-layer is inserted exclusively at the cell poles, exactly where peptidoglycan synthesis occurs. S-layer assembly and growth are tightly coordinated!
1/4🧵 We show across different strains that the S-layer provides mechanical support to the cell wall, especially when it's compromised (such as after lysozyme treatment). The S-layer acts as a protective scaffold, reinforcing the envelope under stress.
July 30, 2025 at 4:54 AM
1/4🧵 We show across different strains that the S-layer provides mechanical support to the cell wall, especially when it's compromised (such as after lysozyme treatment). The S-layer acts as a protective scaffold, reinforcing the envelope under stress.
New preprint from the @remaut-lab.bsky.social ! Happy to share our latest work on a new member of the ENA family, protein fibers found on the spore’s surface. Using CryoID @mikesleutel.bsky.social identified F-ENA in BTK. The paper dives deep into its structure analysis by integrating X-ray and AF3
February 12, 2025 at 12:54 PM
New preprint from the @remaut-lab.bsky.social ! Happy to share our latest work on a new member of the ENA family, protein fibers found on the spore’s surface. Using CryoID @mikesleutel.bsky.social identified F-ENA in BTK. The paper dives deep into its structure analysis by integrating X-ray and AF3