Abhinay Ramaprasad
@abhinay.bsky.social
Malaria biologist. Can stitch together some code. MRC Career Development Fellow at School of Infection and Immunity, UofGlasgow @uofgsii.bsky.social. #NewPI. Fuelled by chai. www.parafugelab.com
Pinned
Abhinay Ramaprasad
@abhinay.bsky.social
· Nov 25
The Parasitologists Unite starter pack is full (150 parasitologists!). Time to open a new one! Keep the suggestions coming and spread the word!
go.bsky.app/KdBboF2
go.bsky.app/KdBboF2
Reposted by Abhinay Ramaprasad
University administration:
"We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible."
Also university administration:
"We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible."
Also university administration:
October 15, 2025 at 3:09 PM
University administration:
"We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible."
Also university administration:
"We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible."
Also university administration:
Reposted by Abhinay Ramaprasad
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
September 11, 2025 at 11:09 AM
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Reposted by Abhinay Ramaprasad
🎥 | WATCH | Dr Francesca Florini (@fra-florini.bsky.social | @weillcornell.bsky.social) discusses the immune evasion in malaria using insights from single-cell analysis of Plasmodium falciparum.
The full GRiP-ing seminar is now available on our YouTube channel:
📺 youtu.be/bKU2Cfv79K8?...
The full GRiP-ing seminar is now available on our YouTube channel:
📺 youtu.be/bKU2Cfv79K8?...
July 28, 2025 at 2:35 PM
🎥 | WATCH | Dr Francesca Florini (@fra-florini.bsky.social | @weillcornell.bsky.social) discusses the immune evasion in malaria using insights from single-cell analysis of Plasmodium falciparum.
The full GRiP-ing seminar is now available on our YouTube channel:
📺 youtu.be/bKU2Cfv79K8?...
The full GRiP-ing seminar is now available on our YouTube channel:
📺 youtu.be/bKU2Cfv79K8?...
Reposted by Abhinay Ramaprasad
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection
phenotypes of the intracellular parasite Cryptosporidium. Hits in the host cholesterol
biosynthesis pathway a...
www.cell.com
July 24, 2025 at 2:08 PM
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
Reposted by Abhinay Ramaprasad
I used inducible CRISPR/Cas9 to make Trypanosoma brucei cell line that allowed me to edit originally muti-copy histone gene. We uncovered a novel role of H4 histone tail in gene regulation. I enjoyed working on this exciting project with @joanarcf.bsky.social, a great mentor.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes - Nature Communications
Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses precision gene editing, site-satur...
www.nature.com
July 6, 2025 at 3:36 PM
I used inducible CRISPR/Cas9 to make Trypanosoma brucei cell line that allowed me to edit originally muti-copy histone gene. We uncovered a novel role of H4 histone tail in gene regulation. I enjoyed working on this exciting project with @joanarcf.bsky.social, a great mentor.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Abhinay Ramaprasad
🎥 | WATCH | Dr Mark Carrington (University of Cambridge) discusses the identification of Trypanosoma brucei gambiense genes that enable resistance to the human trypanolytic lytic factor.
The full Parasitology seminar is now available on our YouTube channel.
📺 www.youtube.com/watch?v=b2QE...
The full Parasitology seminar is now available on our YouTube channel.
📺 www.youtube.com/watch?v=b2QE...
June 27, 2025 at 1:52 PM
🎥 | WATCH | Dr Mark Carrington (University of Cambridge) discusses the identification of Trypanosoma brucei gambiense genes that enable resistance to the human trypanolytic lytic factor.
The full Parasitology seminar is now available on our YouTube channel.
📺 www.youtube.com/watch?v=b2QE...
The full Parasitology seminar is now available on our YouTube channel.
📺 www.youtube.com/watch?v=b2QE...
Reposted by Abhinay Ramaprasad
What happens when the parasite that causes malaria in humans experiences fever-induced heat stress in its host red blood cell?
Check out David Jones' PhD work now on BioRxiv
www.biorxiv.org/content/10.1...
Check out David Jones' PhD work now on BioRxiv
www.biorxiv.org/content/10.1...
www.biorxiv.org
June 23, 2025 at 8:58 AM
What happens when the parasite that causes malaria in humans experiences fever-induced heat stress in its host red blood cell?
Check out David Jones' PhD work now on BioRxiv
www.biorxiv.org/content/10.1...
Check out David Jones' PhD work now on BioRxiv
www.biorxiv.org/content/10.1...
Reposted by Abhinay Ramaprasad
90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
Omaya Dudin
Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why
unicellular organisms evolved multicellularity at the University of Geneva.
www.cell.com
June 10, 2025 at 9:41 AM
90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
Reposted by Abhinay Ramaprasad
🎥 WATCH | Dr Natalia de Miguel (@ndemiguel.bsky.social | @intechchascomus.bsky.social) discusses the role of T. vaginalis extracellular vesicles in cell communication.
A recording of the GRiP-ing seminar can be viewed on our
@uofgsii.bsky.social YouTube channel.
📺 www.youtube.com/watch?v=rGOn...
A recording of the GRiP-ing seminar can be viewed on our
@uofgsii.bsky.social YouTube channel.
📺 www.youtube.com/watch?v=rGOn...
May 23, 2025 at 1:59 PM
🎥 WATCH | Dr Natalia de Miguel (@ndemiguel.bsky.social | @intechchascomus.bsky.social) discusses the role of T. vaginalis extracellular vesicles in cell communication.
A recording of the GRiP-ing seminar can be viewed on our
@uofgsii.bsky.social YouTube channel.
📺 www.youtube.com/watch?v=rGOn...
A recording of the GRiP-ing seminar can be viewed on our
@uofgsii.bsky.social YouTube channel.
📺 www.youtube.com/watch?v=rGOn...
Reposted by Abhinay Ramaprasad
Huge congratulations to @hbelda.bsky.social and David Bradley for their publication on the extraordinarily interesting FIKK kinase family (I am biased) of the malaria causing parasite Plasmodium falciparum. 1/n
May 19, 2025 at 9:20 PM
Huge congratulations to @hbelda.bsky.social and David Bradley for their publication on the extraordinarily interesting FIKK kinase family (I am biased) of the malaria causing parasite Plasmodium falciparum. 1/n
Reposted by Abhinay Ramaprasad
Parasites need mitochondrial respiration to infect and spread. Effective anti-malaria and ani-toxoplasmosis drugs target respiratory complexes (e.g. atovaquone)!
But how do the parasite complexes work and how do drugs inhibit them?
Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇
But how do the parasite complexes work and how do drugs inhibit them?
Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇
Happy to share our latest paper. Result of a great collaboration between @sheinerlab.bsky.social @oninopantsu.bsky.social and Alexander Mühleip’s new group.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex - Nature Structural & Molecular Biology
Here the authors demonstrate that the assembly of mitochondrial respiratory supercomplex (III2–IV) from Toxoplasma gondii is critical for parasite fitness. They reveal the basis for cytochrome b inhib...
www.nature.com
May 19, 2025 at 12:56 PM
Parasites need mitochondrial respiration to infect and spread. Effective anti-malaria and ani-toxoplasmosis drugs target respiratory complexes (e.g. atovaquone)!
But how do the parasite complexes work and how do drugs inhibit them?
Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇
But how do the parasite complexes work and how do drugs inhibit them?
Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇
Reposted by Abhinay Ramaprasad
🎥 | WATCH | Dr Mattie Pawlowic (@goldenpipette.bsky.social) | @dundeeuni.bsky.social) discusses the use of genetics to investigate the Cryptosporidium oocyst.
A recording of the full Parasitology seminar can now be viewed on our @uofgsii.bsky.social YouTube channel.
📺 youtu.be/2ZNNtC4ZWps?...
A recording of the full Parasitology seminar can now be viewed on our @uofgsii.bsky.social YouTube channel.
📺 youtu.be/2ZNNtC4ZWps?...
May 9, 2025 at 12:27 PM
🎥 | WATCH | Dr Mattie Pawlowic (@goldenpipette.bsky.social) | @dundeeuni.bsky.social) discusses the use of genetics to investigate the Cryptosporidium oocyst.
A recording of the full Parasitology seminar can now be viewed on our @uofgsii.bsky.social YouTube channel.
📺 youtu.be/2ZNNtC4ZWps?...
A recording of the full Parasitology seminar can now be viewed on our @uofgsii.bsky.social YouTube channel.
📺 youtu.be/2ZNNtC4ZWps?...
Reposted by Abhinay Ramaprasad
If you have ever wanted to know "Where is the gut is the parasite?" this pre-print is for you. 🐮 Led by Peyton, with thanks to our wonderful collaborators at @moredunfoundation.bsky.social Frank Katzer, @geordieparasit.bsky.social and EMs by @lemgruber.bsky.social www.biorxiv.org/content/10.1...
Tissue atlas of Cryptosporidium parvum infection reveals contrasts between the natural neonatal calf model and laboratory mouse models
Cryptosporidium is an apicomplexan parasite that causes diarrhoeal disease. The species C. parvum is zoonotic and causes significant morbidity and mortality for both humans and farm animals; most comm...
www.biorxiv.org
May 7, 2025 at 11:09 AM
If you have ever wanted to know "Where is the gut is the parasite?" this pre-print is for you. 🐮 Led by Peyton, with thanks to our wonderful collaborators at @moredunfoundation.bsky.social Frank Katzer, @geordieparasit.bsky.social and EMs by @lemgruber.bsky.social www.biorxiv.org/content/10.1...
In case you missed it!
www.youtube.com/watch?v=2ZNN...
www.youtube.com/watch?v=2ZNN...
May 8, 2025 at 6:02 PM
In case you missed it!
www.youtube.com/watch?v=2ZNN...
www.youtube.com/watch?v=2ZNN...
GRiP-ing talk tomorrow from Natalia de Miguel from Instituto Tecnológico de Chascomús (INTECH), Buenos Aires, Argentina. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link: uofglasgow.zoom.us/j/8674596707...
Passcode: 262806
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link: uofglasgow.zoom.us/j/8674596707...
Passcode: 262806
May 1, 2025 at 3:57 PM
GRiP-ing talk tomorrow from Natalia de Miguel from Instituto Tecnológico de Chascomús (INTECH), Buenos Aires, Argentina. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link: uofglasgow.zoom.us/j/8674596707...
Passcode: 262806
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link: uofglasgow.zoom.us/j/8674596707...
Passcode: 262806
Reposted by Abhinay Ramaprasad
GRiP-ing Crypto talk tomorrow from Mattie Pawlowic from the University of Dundee. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
April 24, 2025 at 1:40 PM
GRiP-ing Crypto talk tomorrow from Mattie Pawlowic from the University of Dundee. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
GRiP-ing Crypto talk tomorrow from Mattie Pawlowic from the University of Dundee. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
April 24, 2025 at 1:40 PM
GRiP-ing Crypto talk tomorrow from Mattie Pawlowic from the University of Dundee. Join us!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link- uofglasgow.zoom.us/j/8172068584...
Passcode: 038661
Reposted by Abhinay Ramaprasad
A GRIP-ing and Tryp-ing seminar tomorrow - Joana Faria from the University of York!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
April 10, 2025 at 1:23 PM
A GRIP-ing and Tryp-ing seminar tomorrow - Joana Faria from the University of York!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
A GRIP-ing and Tryp-ing seminar tomorrow - Joana Faria from the University of York!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
April 10, 2025 at 1:23 PM
A GRIP-ing and Tryp-ing seminar tomorrow - Joana Faria from the University of York!
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
2 pm (GMT) | 3 pm (CET) | 9 am (EDT)
Link - uofglasgow.zoom.us/j/8897218018...
Passcode: 987702
Don't miss @reecelab.bsky.social interesting talk on why malaria parasites are crazy sticklers to routines and schedules.
🎥 | WATCH | Professor Sarah Reece (@edinburghuni.bsky.social) explains how daily rhythms matter to malaria parasites.
A recording of the full Parasitology
GRiP-ing seminar can now be viewed on our @uofgsii.bsky.social YouTube channel for a limited time.
youtu.be/OwV82b0oEj4?...
A recording of the full Parasitology
GRiP-ing seminar can now be viewed on our @uofgsii.bsky.social YouTube channel for a limited time.
youtu.be/OwV82b0oEj4?...
April 3, 2025 at 3:44 PM
Don't miss @reecelab.bsky.social interesting talk on why malaria parasites are crazy sticklers to routines and schedules.
Reposted by Abhinay Ramaprasad
It’s 9am TFT time here, and citizens are already gathering to protest Tariffs by the United States. Our plain clothes Officer Penguins are attempting to maintain calm, but unfortunately we keep losing them in the crowd.
April 3, 2025 at 4:13 AM
It’s 9am TFT time here, and citizens are already gathering to protest Tariffs by the United States. Our plain clothes Officer Penguins are attempting to maintain calm, but unfortunately we keep losing them in the crowd.
"I don't care if the analysis shows no differential expression. I have to give a talk tomorrow and I want to show these genes are upregulated. Just divide column D by column C and send me the results"
www.nytimes.com/2025/04/02/b...
www.nytimes.com/2025/04/02/b...
How Are Trump’s Tariff Rates Calculated?
The answer appears to begin with the total trade deficit America runs with its trading partners.
www.nytimes.com
April 3, 2025 at 10:00 AM
"I don't care if the analysis shows no differential expression. I have to give a talk tomorrow and I want to show these genes are upregulated. Just divide column D by column C and send me the results"
www.nytimes.com/2025/04/02/b...
www.nytimes.com/2025/04/02/b...
Reposted by Abhinay Ramaprasad
GRIP-ing seminar this Friday from André Schneider from University of Bern. Don't miss it!
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
March 26, 2025 at 11:44 AM
GRIP-ing seminar this Friday from André Schneider from University of Bern. Don't miss it!
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
Reposted by Abhinay Ramaprasad
Ten years of bigger samples, better views mcgovern.mit.edu/2025/03/03/t...
Thank you for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans. @benliffner.bsky.social @jvr-lab.bsky.social
Thank you for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans. @benliffner.bsky.social @jvr-lab.bsky.social
Ten years of bigger samples, better views - MIT McGovern Institute
Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons they had seen under the microscopes of the time. With today’s imaging tech...
mcgovern.mit.edu
March 26, 2025 at 8:25 PM
Ten years of bigger samples, better views mcgovern.mit.edu/2025/03/03/t...
Thank you for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans. @benliffner.bsky.social @jvr-lab.bsky.social
Thank you for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans. @benliffner.bsky.social @jvr-lab.bsky.social
GRIP-ing seminar this Friday from André Schneider from University of Bern. Don't miss it!
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
March 26, 2025 at 11:44 AM
GRIP-ing seminar this Friday from André Schneider from University of Bern. Don't miss it!
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619
Link: uofglasgow.zoom.us/j/8255427338...
Passcode: 984619