Abdou Akkouche
@abdouak.bsky.social
Transposable elements, Chromatin, piRNAs, Drosophila/iGRED-Clermont FERRAND
Reposted by Abdou Akkouche
Hi! Florence Hommais, @nicolasparisot.bsky.social , and I are looking for a postdoctoral candidate to investigate the molecular dialogue between three weevil species and their endosymbiotic bacteria #symbiosis! Please see the #post-doc offer for more information. #SymbioSky #Bioinformatics
November 3, 2025 at 11:50 AM
Hi! Florence Hommais, @nicolasparisot.bsky.social , and I are looking for a postdoctoral candidate to investigate the molecular dialogue between three weevil species and their endosymbiotic bacteria #symbiosis! Please see the #post-doc offer for more information. #SymbioSky #Bioinformatics
Reposted by Abdou Akkouche
piRNAs are essential for transposon silencing in the animal germline.
But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response?
Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.
But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response?
Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.
Antisense transposon insertions into host genes trigger piRNA mediated immunity https://www.biorxiv.org/content/10.1101/2025.07.28.667215v1
August 3, 2025 at 3:39 PM
piRNAs are essential for transposon silencing in the animal germline.
But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response?
Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.
But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response?
Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.
Reposted by Abdou Akkouche
Honored to see our work highlighted in this News & Views by Germano Cecere @cecerelab.bsky.social and @arantxarojas.bsky.social in @natsmb.nature.com!
A great read on how H3K27me3 shapes piRNA transcription in 🪱 worms and 🪰 flies. rdcu.be/euuRJ
A great read on how H3K27me3 shapes piRNA transcription in 🪱 worms and 🪰 flies. rdcu.be/euuRJ
H3K27me3 expands the epigenetic control of piRNA transcription
Nature Structural & Molecular Biology - Constitutive heterochromatin can promote piRNA transcription, a crucial step in genome defense. Two studies now show that piRNA transcription in...
rdcu.be
July 2, 2025 at 3:09 PM
Honored to see our work highlighted in this News & Views by Germano Cecere @cecerelab.bsky.social and @arantxarojas.bsky.social in @natsmb.nature.com!
A great read on how H3K27me3 shapes piRNA transcription in 🪱 worms and 🪰 flies. rdcu.be/euuRJ
A great read on how H3K27me3 shapes piRNA transcription in 🪱 worms and 🪰 flies. rdcu.be/euuRJ
Reposted by Abdou Akkouche
A little late to share, but still thrilled 🤗!
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
New online: Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks
Nature Structural & Molecular Biology, Published online: 17 June 2025; doi:10.1038/s41594-025-01584-8The authors reveal that, in fruit fly ovaries, the protein Rhino is guided to specific regions of the genome by a combination of two histone modifications, enhancing understanding of how cells protect their DNA from harmful virus-like elements.
go.nature.com
July 2, 2025 at 3:09 PM
A little late to share, but still thrilled 🤗!
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇
What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters.
When forces unite…
👇👇👇