Abby Buchwalter
@abbybuch.bsky.social
Associate professor at UCSF. Cell biologist at heart, research focus on the function and dynamic regulation of the nuclear periphery.
www.buchwalterlab.UCSF.edu.
www.buchwalterlab.UCSF.edu.
And yep - we found that the nuclear membrane protein LAP2b cooperates with lamin B1 to maintain nuclear integrity. When both are depleted, we see lamina defects and nuclear ruptures that look like this (cyan is nuclear lamina, magenta is nuclear integrity reporter): (5/n)
July 21, 2025 at 5:49 PM
And yep - we found that the nuclear membrane protein LAP2b cooperates with lamin B1 to maintain nuclear integrity. When both are depleted, we see lamina defects and nuclear ruptures that look like this (cyan is nuclear lamina, magenta is nuclear integrity reporter): (5/n)