Frances Arnold
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francesarnold.bsky.social
Frances Arnold
@francesarnold.bsky.social
6.8K followers 120 following 46 posts

Engineer/scientist, Nobel Prize in Chemistry 2018
I love evolution, enzymes, protein engineering, AI
Linus Pauling Professor at Caltech

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Frances Hamilton Arnold is an American chemical engineer and Nobel Laureate. She is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology (Caltech). In 2018, she was awarded the Nobel Prize in Chemistry for pioneering the use of directed evolution to engineer enzymes. .. more

Biology 27%
Chemistry 19%
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Reposted by Frances H. Arnold

anima-anandkumar.bsky.social
Anima Anandkumar @anima-anandkumar.bsky.social · 10d
An exciting collaboration with @francesarnold.bsky.social on AI+enzymes. This combines generative protein models with carefully tuned filters that resulted in functional and versatile enzymes beating natural and previously engineered enzymes.
francesarnold.bsky.social Frances Arnold @francesarnold.bsky.social · 10d
Generated PLP-dependent Trp synthases are functional, stable, and exhibit usefully broad substrate scopes! fun collaboration with @anima-anandkumar.bsky.social @ramanathanlab.bsky.social Amin Takavoli. I love AI + #enzymes!
kevinkaichuang.bsky.social Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 10d
Finetune a codon-level language model with 30k tryptophan synthases, then generate diverse, functional, enzymes with broad substrate scopes.

Théophile Lambert @jsunn-y.bsky.social @francesarnold.bsky.social

www.biorxiv.org/content/10.1...

Reposted by Anima Anandkumar

francesarnold.bsky.social
Frances Arnold @francesarnold.bsky.social · 10d
Generated PLP-dependent Trp synthases are functional, stable, and exhibit usefully broad substrate scopes! fun collaboration with @anima-anandkumar.bsky.social @ramanathanlab.bsky.social Amin Takavoli. I love AI + #enzymes!
kevinkaichuang.bsky.social Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 10d
Finetune a codon-level language model with 30k tryptophan synthases, then generate diverse, functional, enzymes with broad substrate scopes.

Théophile Lambert @jsunn-y.bsky.social @francesarnold.bsky.social

www.biorxiv.org/content/10.1...

Reposted by Anima Anandkumar, Frances H. Arnold

kevinkaichuang.bsky.social
Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 10d
Finetune a codon-level language model with 30k tryptophan synthases, then generate diverse, functional, enzymes with broad substrate scopes.

Théophile Lambert @jsunn-y.bsky.social @francesarnold.bsky.social

www.biorxiv.org/content/10.1...

Reposted by Frances H. Arnold

Reposted by Frances H. Arnold

kevinkaichuang.bsky.social
Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 14d
Enzyme Engineering Database (EnzEngDB): a platform for sharing and interpreting sequence–function relationships across protein engineering campaigns

@francescazfl.bsky.social @jsunn-y.bsky.social @francesarnold.bsky.social @arianemora.bsky.social

Paper: doi.org/10.1093/nar/...
DB: enzengdb.org

Reposted by Frances H. Arnold

Reposted by Frances H. Arnold

francesarnold.bsky.social
Frances Arnold @francesarnold.bsky.social · 28d
Thank you, Gianluca. The pleasure was all mine. What a great meeting in a magical location.

francesarnold.bsky.social
Frances Arnold @francesarnold.bsky.social · Oct 19
Friday night at Adams pack station. 9 miles and a century from @caltech.

Reposted by Frances H. Arnold

chemistryworld.com
Chemistry World @chemistryworld.com · Oct 19
A new round of layoffs at Nasa’s jet propulsion lab will result in ‘an untold loss of scientific knowledge and expertise’ according to congresswoman Judy Chu.
Nasa’s Jet Propulsion Lab and home of Mars rovers loses 10% of its staff
The dismissal of 550 JPL workers is the fourth round of recent layoffs at the lab, prompting fears of a brain drain
www.chemistryworld.com

Reposted by Frances H. Arnold