Bogi
@zbobo2.bsky.social
Reposted by Bogi
🧬 New paper in Nature Communications!
We found that POLE2,part of DNA polymerase ε,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair.
The interactome is more interconnected than thought.
@teamgogl.bsky.social 🇫🇮🇫🇷🇭🇺🇬🇧
www.nature.com/articles/s41...
We found that POLE2,part of DNA polymerase ε,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair.
The interactome is more interconnected than thought.
@teamgogl.bsky.social 🇫🇮🇫🇷🇭🇺🇬🇧
www.nature.com/articles/s41...
December 15, 2025 at 11:58 AM
🧬 New paper in Nature Communications!
We found that POLE2,part of DNA polymerase ε,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair.
The interactome is more interconnected than thought.
@teamgogl.bsky.social 🇫🇮🇫🇷🇭🇺🇬🇧
www.nature.com/articles/s41...
We found that POLE2,part of DNA polymerase ε,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair.
The interactome is more interconnected than thought.
@teamgogl.bsky.social 🇫🇮🇫🇷🇭🇺🇬🇧
www.nature.com/articles/s41...
Reposted by Bogi
Happy to share that our paper describing a new motif-mediated interactome is out in Nature Communications
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein - Nature Communications
Short linear motifs in disordered protein regions are involved numerous protein–protein interactions. Here, the authors find that the POLE2 subunit of human DNA polymerase ε acts as a motif binding pr...
www.nature.com
December 15, 2025 at 8:41 AM
Happy to share that our paper describing a new motif-mediated interactome is out in Nature Communications
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Bogi
profaff.fr
The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.
The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.
ProfAffv2 - Protein Affinity Database
profaff.fr
October 28, 2025 at 8:04 AM
profaff.fr
The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.
The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.
I’m thrilled to share that I have secured a permanent position within Section 20 of the CNRS. I will do my utmost to advance our understanding of the intricate interactome of transcription factors, an area of research I am deeply passionate about. 🎆
Congratulations to Boglarka for obtaining a CNRS permanent position! 🎉🥂 She will start a new line of research in the Gogl lab focusing on the quantitative interactomics and biophysics of protein-DNA interactions and their consequences on transcription regulation and chromatin organization.
June 12, 2025 at 8:49 AM
I’m thrilled to share that I have secured a permanent position within Section 20 of the CNRS. I will do my utmost to advance our understanding of the intricate interactome of transcription factors, an area of research I am deeply passionate about. 🎆
Reposted by Bogi