Yifei Du
@yifeidu.bsky.social
RNA Structure & Design | Co-Founder & Head of Research @RNAvate. Prev: @MRC-LMB @LeverhulmeTrust @IBP
Pinned
Yifei Du
@yifeidu.bsky.social
· Jan 23
Rolling toward circular solutions - Nature Chemical Biology
Nature Chemical Biology - Rolling toward circular solutions
www.nature.com
Thanks to @nchembio.bsky.social for highlighting our research on circular RNA and rolling circle translation: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....
Our latest work from the Venki Lab on translation initiation in endogenous circular RNAs is now available on bioRxiv! A great collaboration with Philipp Zuber (@zuber-phil15.bsky.social) and Xueyan Li!
Mechanism of translation initiation on endogenous eukaryotic circular RNAs https://www.biorxiv.org/content/10.1101/2025.10.31.685782v1
November 3, 2025 at 7:20 PM
Our latest work from the Venki Lab on translation initiation in endogenous circular RNAs is now available on bioRxiv! A great collaboration with Philipp Zuber (@zuber-phil15.bsky.social) and Xueyan Li!
Reposted by Yifei Du
This one is a bit of a departure from the usual and definitely a work in progress!
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
September 13, 2025 at 12:05 AM
This one is a bit of a departure from the usual and definitely a work in progress!
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
Thanks to @nchembio.bsky.social for highlighting our research on circular RNA and rolling circle translation: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....
Rolling toward circular solutions - Nature Chemical Biology
Nature Chemical Biology - Rolling toward circular solutions
www.nature.com
January 23, 2025 at 7:44 PM
Thanks to @nchembio.bsky.social for highlighting our research on circular RNA and rolling circle translation: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....
Original research paper is here: www.nature.com/articles/s41....