Yu Xiao (肖燏)
@xiaoyucaly.bsky.social
Postdoctoral researcher in DeMON lab, Lund University | Machine learning | Alzheimer’s Disease pregression modeling | multimodality neuroimaging
Reposted by Yu Xiao (肖燏)
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 2:22 AM
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
How could we predict multiple neurodegenerative disease using just blood sample and a single model? Check out this incredible work by @anlijuncn.bsky.social ⬇️
Can AI reveal risk & co-pathology of multiple neurodegenerative diseases from a single blood sample? We explored AI-based diagnostic power on high rank plasma proteomics (N=17,170). www.medrxiv.org/content/10.1... #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #neurology
Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people
Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathologi...
www.medrxiv.org
July 17, 2025 at 9:26 AM
How could we predict multiple neurodegenerative disease using just blood sample and a single model? Check out this incredible work by @anlijuncn.bsky.social ⬇️
How does brain change functionally in AD and aging? Check out this cool work from @jorittmo.bsky.social
How does the brain reorganize in the context of age and AD?
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
Are functional changes in age and AD similar?
Are these changes dynamic across the age/AD spectrum?
We unpack these questions in a sample of N=973 with AD biomarkers
Preprint: tinyurl.com/ymv8s7h8
⬇️🧵
1/
May 27, 2025 at 1:58 PM
How does brain change functionally in AD and aging? Check out this cool work from @jorittmo.bsky.social
Reposted by Yu Xiao (肖燏)
Preprint 🥳
"A unified imaging-histology framework for superficial white matter architecture studies in the human brain"
🧠 SMW key for brain structure-function links
🤔 understudied because of its complexity
💡 SMW mapping for histology & MRI
🌟 OA
📖 lnkd.in/ef8bGGrF
by Youngeun Hwang et al
"A unified imaging-histology framework for superficial white matter architecture studies in the human brain"
🧠 SMW key for brain structure-function links
🤔 understudied because of its complexity
💡 SMW mapping for histology & MRI
🌟 OA
📖 lnkd.in/ef8bGGrF
by Youngeun Hwang et al
May 11, 2025 at 2:24 AM
Preprint 🥳
"A unified imaging-histology framework for superficial white matter architecture studies in the human brain"
🧠 SMW key for brain structure-function links
🤔 understudied because of its complexity
💡 SMW mapping for histology & MRI
🌟 OA
📖 lnkd.in/ef8bGGrF
by Youngeun Hwang et al
"A unified imaging-histology framework for superficial white matter architecture studies in the human brain"
🧠 SMW key for brain structure-function links
🤔 understudied because of its complexity
💡 SMW mapping for histology & MRI
🌟 OA
📖 lnkd.in/ef8bGGrF
by Youngeun Hwang et al
Reposted by Yu Xiao (肖燏)
Check out Xiaoyu’s fantastic work!!
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
www.biorxiv.org
May 2, 2025 at 9:51 AM
Check out Xiaoyu’s fantastic work!!
Reposted by Yu Xiao (肖燏)
Really important and cool work by @xiaoyucaly.bsky.social! Congratulations!
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
www.biorxiv.org
April 28, 2025 at 8:05 AM
Really important and cool work by @xiaoyucaly.bsky.social! Congratulations!
Reposted by Yu Xiao (肖燏)
‼️New preprint!
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
April 25, 2025 at 9:35 AM
‼️New preprint!
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
We are happy to share our latest work led by @teanijarv.bsky.social investigating why tau pathology in AD often accumulates more in one hemisphere of the brain than the other.
Check out 🔗https://biorxiv.org/content/10.1101/2025.04.15.648728v1 or dive into the details below👇
Reposted by Yu Xiao (肖燏)
🧠Exciting new findings from a great collaboration between the BioFINDER study and the talented
@xiaoyucaly.bsky.social from @jwvogel.bsky.social group!! In their preprint, they show that tau presence and tau load are guided by unique brain mechanisms. Dive into the details here 👇
@xiaoyucaly.bsky.social from @jwvogel.bsky.social group!! In their preprint, they show that tau presence and tau load are guided by unique brain mechanisms. Dive into the details here 👇
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
www.biorxiv.org
April 25, 2025 at 9:38 AM
🧠Exciting new findings from a great collaboration between the BioFINDER study and the talented
@xiaoyucaly.bsky.social from @jwvogel.bsky.social group!! In their preprint, they show that tau presence and tau load are guided by unique brain mechanisms. Dive into the details here 👇
@xiaoyucaly.bsky.social from @jwvogel.bsky.social group!! In their preprint, they show that tau presence and tau load are guided by unique brain mechanisms. Dive into the details here 👇
Reposted by Yu Xiao (肖燏)
I am so very proud announce my lab's first preprint!!
@xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution:
* Tau sequence driven by connectivity dynamics
* Tau load driven by local factors
Check out her thread below
@xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution:
* Tau sequence driven by connectivity dynamics
* Tau load driven by local factors
Check out her thread below
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
www.biorxiv.org
April 24, 2025 at 9:24 PM
I am so very proud announce my lab's first preprint!!
@xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution:
* Tau sequence driven by connectivity dynamics
* Tau load driven by local factors
Check out her thread below
@xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution:
* Tau sequence driven by connectivity dynamics
* Tau load driven by local factors
Check out her thread below
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
www.biorxiv.org
April 24, 2025 at 7:42 PM
🧠New preprint! What drives tau, the pathological protein in AD, to spread?
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology
We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out: www.biorxiv.org/content/10.1...
#MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology