Walid Khaled
@wtklab.bsky.social
Professor at University of Cambridge Department of Pharmacology and Cambridge Stem Cell Institute. Fellow of Magdalene College.
Ageing, Resilience and Cancer Prevention
www.wtklab.com
Ageing, Resilience and Cancer Prevention
www.wtklab.com
Reposted by Walid Khaled
Really happy to share a link to our work showing that anti-progestin therapy could help prevent breast cancer before menopause.
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science
Anti-progestin therapy targets hallmarks of breast cancer risk
Nature - Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing...
urldefense.com
November 5, 2025 at 9:07 PM
Really happy to share a link to our work showing that anti-progestin therapy could help prevent breast cancer before menopause.
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science
Reposted by Walid Khaled
So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis!
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social
It just came out online, check it out here:
rdcu.be/eIIKD
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social
It just came out online, check it out here:
rdcu.be/eIIKD
Contractile fibroblasts form a transient niche for the branching mammary epithelium
Nature Communications - Fibroblasts represent a heterogenous cell population but how their differences reflect their plasticity and origin is not fully understood. Here, the authors map the origin...
rdcu.be
September 29, 2025 at 4:34 PM
So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis!
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social
It just came out online, check it out here:
rdcu.be/eIIKD
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social
It just came out online, check it out here:
rdcu.be/eIIKD
Reposted by Walid Khaled
Geometry first: how positional cues dictate fate in bilayered epithelia thenode.biologists.com/geometry-fir...
Geometry first: how positional cues dictate fate in bilayered epithelia - the Node
Behind the paper story focussed on research on early fate decisions in bilayered epithelia.
thenode.biologists.com
September 9, 2025 at 7:12 AM
Geometry first: how positional cues dictate fate in bilayered epithelia thenode.biologists.com/geometry-fir...
Reposted by Walid Khaled
Congratulations to the team on all their hard work on developing this first of its kind model! @andreaventura.bsky.social @psalmotoxin.bsky.social @wtklab.bsky.social
@kytsailab.bsky.social @moffittnews.bsky.social
@kytsailab.bsky.social @moffittnews.bsky.social
Now online in Cancer Discovery @aacrjournals.bsky.social: An Autochthonous Model of Lung Cancer Identifies Requirements for Cellular Transformation in the Naked Mole-Rat - by Alyssa Shepard, Daniel Lester, @kissillab.bsky.social,
and colleagues doi.org/10.1158/2159... @moffittnews.bsky.social
and colleagues doi.org/10.1158/2159... @moffittnews.bsky.social
September 8, 2025 at 5:53 PM
Congratulations to the team on all their hard work on developing this first of its kind model! @andreaventura.bsky.social @psalmotoxin.bsky.social @wtklab.bsky.social
@kytsailab.bsky.social @moffittnews.bsky.social
@kytsailab.bsky.social @moffittnews.bsky.social
Reposted by Walid Khaled
Could this be the future of cancer prevention?
Walid Khaled, a new ERC Advanced Grant recipient @cam.ac.uk, will work on a preventive vaccine for breast cancer.
Learn more 👉 buff.ly/s6cBCwL
#ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social
Walid Khaled, a new ERC Advanced Grant recipient @cam.ac.uk, will work on a preventive vaccine for breast cancer.
Learn more 👉 buff.ly/s6cBCwL
#ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social
June 17, 2025 at 11:02 AM
Could this be the future of cancer prevention?
Walid Khaled, a new ERC Advanced Grant recipient @cam.ac.uk, will work on a preventive vaccine for breast cancer.
Learn more 👉 buff.ly/s6cBCwL
#ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social
Walid Khaled, a new ERC Advanced Grant recipient @cam.ac.uk, will work on a preventive vaccine for breast cancer.
Learn more 👉 buff.ly/s6cBCwL
#ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social
Thank you @erc.europa.eu for highlighting PreBRCATx. I am excited where this grant will take will take our science - hopefully a step closer to therapeutic cancer prevention!
The 2024 ERC Advanced Grants will help 281 researchers set up their own teams and conduct research on the topics of their choice.
We selected 5 examples of projects; based in Spain, the Netherlands, Germany and the UK.
Find out more 👉 buff.ly/Kuo67XK
We selected 5 examples of projects; based in Spain, the Netherlands, Germany and the UK.
Find out more 👉 buff.ly/Kuo67XK
June 17, 2025 at 10:17 AM
Thank you @erc.europa.eu for highlighting PreBRCATx. I am excited where this grant will take will take our science - hopefully a step closer to therapeutic cancer prevention!
Our latest paper from is out! Congratulations to all members the lab that contributed over the years!
No UMAPs in this one!
@phar.cam.ac.uk @scicambridge.bsky.social
Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social
No UMAPs in this one!
@phar.cam.ac.uk @scicambridge.bsky.social
Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social
CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer
@wtklab.bsky.social and collaborators
www.embopress.org/doi/full/10....
@wtklab.bsky.social and collaborators
www.embopress.org/doi/full/10....
May 6, 2025 at 2:22 PM
Our latest paper from is out! Congratulations to all members the lab that contributed over the years!
No UMAPs in this one!
@phar.cam.ac.uk @scicambridge.bsky.social
Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social
No UMAPs in this one!
@phar.cam.ac.uk @scicambridge.bsky.social
Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social
Reposted by Walid Khaled
Join our Prevention Primer on 24 June and grow your knowledge ahead of @cancerresearchuk.org's #PrevConf25. Hear from Prof Peter Sasieni, @sarahblagden.bsky.social, @wtklab.bsky.social and others, inc lab scientists, clinicians, behavioural scientists and epidemiologists.
bit.ly
April 14, 2025 at 9:30 AM
Join our Prevention Primer on 24 June and grow your knowledge ahead of @cancerresearchuk.org's #PrevConf25. Hear from Prof Peter Sasieni, @sarahblagden.bsky.social, @wtklab.bsky.social and others, inc lab scientists, clinicians, behavioural scientists and epidemiologists.
Check out the final programme for ENBDC (23-26 April) now with 7 short talks selected from the abstracts.
Last 8 spots still available but you need to be quick! We can accept applications till 31st March.
Last 8 spots still available but you need to be quick! We can accept applications till 31st March.
Workshop | ENBDC
enbdc.org
March 28, 2025 at 8:00 PM
Check out the final programme for ENBDC (23-26 April) now with 7 short talks selected from the abstracts.
Last 8 spots still available but you need to be quick! We can accept applications till 31st March.
Last 8 spots still available but you need to be quick! We can accept applications till 31st March.
Reposted by Walid Khaled
We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social
March 20, 2025 at 2:04 PM
We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social
Reposted by Walid Khaled
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Linsey Porter in our lab is running the Cambridge half marathon for this worthy cause 👇👇. Please support if you can.
www.givengain.com/project/lins...
www.givengain.com/project/lins...
Music therapy for those living with dementia
Hello everyone! My name is Linsey, and my husband Alan and I are excited to support the Saffron Hall Trust through my fundraising campaign on GivenGain. The Trust uses music therapy for many different...
www.givengain.com
March 5, 2025 at 9:04 AM
Linsey Porter in our lab is running the Cambridge half marathon for this worthy cause 👇👇. Please support if you can.
www.givengain.com/project/lins...
www.givengain.com/project/lins...
JOB ALERT (9 days to go)
We are looking for a computational postdoc to lead on the analysis of the NMGN Ageing Cluster spatial transcriptomics dataset.
Start date: Flexible
Tenure: 3 years
Deadline: 28th Feb 2025
Informal queries welcome!
Please RT
We are looking for a computational postdoc to lead on the analysis of the NMGN Ageing Cluster spatial transcriptomics dataset.
Start date: Flexible
Tenure: 3 years
Deadline: 28th Feb 2025
Informal queries welcome!
Please RT
JOB ALERT
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
February 19, 2025 at 2:17 PM
JOB ALERT (9 days to go)
We are looking for a computational postdoc to lead on the analysis of the NMGN Ageing Cluster spatial transcriptomics dataset.
Start date: Flexible
Tenure: 3 years
Deadline: 28th Feb 2025
Informal queries welcome!
Please RT
We are looking for a computational postdoc to lead on the analysis of the NMGN Ageing Cluster spatial transcriptomics dataset.
Start date: Flexible
Tenure: 3 years
Deadline: 28th Feb 2025
Informal queries welcome!
Please RT
Deadline extended to 28th Feb!
JOB ALERT
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
February 13, 2025 at 9:02 AM
Deadline extended to 28th Feb!
JOB ALERT
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
January 15, 2025 at 2:54 PM
JOB ALERT
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster.
www.jobs.cam.ac.uk/job/49939/
@scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
Reposted by Walid Khaled
🚨 Excited to announce that we are hiring 🚨
If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃
This ChatGPT image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch
If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃
This ChatGPT image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch
December 23, 2024 at 11:30 AM
🚨 Excited to announce that we are hiring 🚨
If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃
This ChatGPT image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch
If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃
This ChatGPT image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch
Registration is now open for the 16th ENBDC workshop 24-26 April 2025
Great line-up of speakers 👇
6 selected talks from abstracts ✍️
Limited spaces available. Sign up early to avoid disappointment!
enbdc.org/workshop/
Great line-up of speakers 👇
6 selected talks from abstracts ✍️
Limited spaces available. Sign up early to avoid disappointment!
enbdc.org/workshop/
December 16, 2024 at 2:48 PM
Registration is now open for the 16th ENBDC workshop 24-26 April 2025
Great line-up of speakers 👇
6 selected talks from abstracts ✍️
Limited spaces available. Sign up early to avoid disappointment!
enbdc.org/workshop/
Great line-up of speakers 👇
6 selected talks from abstracts ✍️
Limited spaces available. Sign up early to avoid disappointment!
enbdc.org/workshop/
Reposted by Walid Khaled
We are forming a patient advisory group to help shape our research on BRCA breast cancer prevention! Follow the link/scan the barcode for more info and to express interest. Please share! @wtklab.bsky.social
www.stemcells.cam.ac.uk/about-us/eng...
www.stemcells.cam.ac.uk/about-us/eng...
November 26, 2024 at 3:53 PM
We are forming a patient advisory group to help shape our research on BRCA breast cancer prevention! Follow the link/scan the barcode for more info and to express interest. Please share! @wtklab.bsky.social
www.stemcells.cam.ac.uk/about-us/eng...
www.stemcells.cam.ac.uk/about-us/eng...
First post on here!
Looking forward to sharing what we learnt over the years from studying the mouse and human breast at the single cell level!
@crukcamcentre.bsky.social
@sabcs.bsky.social
@cancerresearchuk.org
www.sabcsmeetingnews.org/plenary-lect...
Looking forward to sharing what we learnt over the years from studying the mouse and human breast at the single cell level!
@crukcamcentre.bsky.social
@sabcs.bsky.social
@cancerresearchuk.org
www.sabcsmeetingnews.org/plenary-lect...
Plenary Lecture to explore breast cell atlas in cancer prevention, treatment - SABCS Meeting News
Walid Khaled, PhD, will deliver the second plenary lecture during the 2024 San Antonio Breast Cancer Symposium® about cell atlases as roadmaps in cancer immunology.
www.sabcsmeetingnews.org
November 26, 2024 at 12:02 PM
First post on here!
Looking forward to sharing what we learnt over the years from studying the mouse and human breast at the single cell level!
@crukcamcentre.bsky.social
@sabcs.bsky.social
@cancerresearchuk.org
www.sabcsmeetingnews.org/plenary-lect...
Looking forward to sharing what we learnt over the years from studying the mouse and human breast at the single cell level!
@crukcamcentre.bsky.social
@sabcs.bsky.social
@cancerresearchuk.org
www.sabcsmeetingnews.org/plenary-lect...
Reposted by Walid Khaled
Earlier this year, we published an article in Cancer Discovery discussing six hallmarks of precancer and highlighting the need for a multi-omics approach to research in this area. aacrjournals.org/cancerdiscov...
Would love to connect with others working in this area!
Would love to connect with others working in this area!
The Hallmarks of Precancer
Summary:. Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the need for risk stratification to...
aacrjournals.org
November 15, 2024 at 4:37 PM
Earlier this year, we published an article in Cancer Discovery discussing six hallmarks of precancer and highlighting the need for a multi-omics approach to research in this area. aacrjournals.org/cancerdiscov...
Would love to connect with others working in this area!
Would love to connect with others working in this area!