Daniel Wrapp
@wrapplab.bsky.social
Host-pathogen interactions, structural biology, protein design and more. Assistant Professor at Duke University.
www.wrapplab.org
www.wrapplab.org
Reposted by Daniel Wrapp
It's really real 😭😭😭 Huge thanks to Wrapper's Delight ( @wrapplab.bsky.social ) and T-Pain ( @timothysheahan.bsky.social ) for everything. Working on this together was the best part of 2025!
Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...
Client Challenge
www.nature.com
January 10, 2026 at 2:42 PM
It's really real 😭😭😭 Huge thanks to Wrapper's Delight ( @wrapplab.bsky.social ) and T-Pain ( @timothysheahan.bsky.social ) for everything. Working on this together was the best part of 2025!
Reposted by Daniel Wrapp
Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...
Client Challenge
www.nature.com
January 10, 2026 at 1:06 PM
Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...
Reposted by Daniel Wrapp
A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
www.nature.com/articles/s42...
@wrapplab.bsky.social
www.nature.com/articles/s42...
@wrapplab.bsky.social
January 9, 2026 at 1:22 PM
A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
www.nature.com/articles/s42...
@wrapplab.bsky.social
www.nature.com/articles/s42...
@wrapplab.bsky.social
Reposted by Daniel Wrapp
Excited to share a new publication from my PhD labs where we explore a method to improve antibody-mediated protection against herpes simplex virus infections: www.science.org/doi/10.1126/...
Eliminating interactions with the viral Fc receptor improves antibody-mediated protection against neonatal HSV infection in mice
HSV-specific antibodies demonstrate improved activity in vitro and in vivo when the IgG Fc domain is rendered insensitive to the viral Fc receptor.
www.science.org
November 19, 2025 at 7:04 PM
Excited to share a new publication from my PhD labs where we explore a method to improve antibody-mediated protection against herpes simplex virus infections: www.science.org/doi/10.1126/...
Reposted by Daniel Wrapp
I'm honored to receive a MacArthur Fellowship. As always, I extend my sincerest thanks to all my wonderful mentors, colleagues, collaborators, admins, and trainees who make this work possible. #MacFellow
UT Austin has a new “genius grant” recipient!
Texas Science professor Jason McLellan has been awarded a MacArthur Fellowship — aka the “genius grant” — by The MacArthur Foundation.
#TexasScience @mclellanlab.bsky.social #MacArthurGenius @utaustin.bsky.social
cns.utexas.edu/news/accolad...
Texas Science professor Jason McLellan has been awarded a MacArthur Fellowship — aka the “genius grant” — by The MacArthur Foundation.
#TexasScience @mclellanlab.bsky.social #MacArthurGenius @utaustin.bsky.social
cns.utexas.edu/news/accolad...
Virus Slayer Awarded ‘Genius Grant’ by MacArthur Foundation
The award recognizes Jason McLellan’s work to investigate how viruses infect our cells and to develop new treatments for infectious disease.
cns.utexas.edu
October 8, 2025 at 7:59 PM
I'm honored to receive a MacArthur Fellowship. As always, I extend my sincerest thanks to all my wonderful mentors, colleagues, collaborators, admins, and trainees who make this work possible. #MacFellow
Reposted by Daniel Wrapp
As part of our 2025 “Rising Stars in #Vaccinology and #Immunity to #Microbes” seminar series, we spoke with Dr. Daniel Wrapp @wrapplab.bsky.social who uses structure-based design to develop new #antiviral therapies. cvimp.podbean.com/e/episode-13...
Episode 13: Using structure-based design to develop novel antiviral therapeutics | Creating Memory: Vaccines & Immunity
We talk with Dr. Daniel Wrapp, Assistant Professor Assistant Professor at the Duke Human Vaccine Institute at Duke University School of Medicine, NC, who uses structure-based design to develop novel t...
cvimp.podbean.com
September 2, 2025 at 2:13 AM
As part of our 2025 “Rising Stars in #Vaccinology and #Immunity to #Microbes” seminar series, we spoke with Dr. Daniel Wrapp @wrapplab.bsky.social who uses structure-based design to develop new #antiviral therapies. cvimp.podbean.com/e/episode-13...
Reposted by Daniel Wrapp
Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.
June 18, 2025 at 2:24 PM
Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.
Reposted by Daniel Wrapp
Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen www.biorxiv.org/content/10.1101/2025.05.19.654955v1 #cryoem
May 20, 2025 at 7:10 AM
Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen www.biorxiv.org/content/10.1101/2025.05.19.654955v1 #cryoem
Very excited to share our latest preprint describing the isolation and characterization of neutralizing HCoV-229E-directed antibodies from a human donor! Great collaboration between DHVI and the Baric and Sheahan (@timothysheahan.bsky.social) labs at UNC.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
HCoV-229E is an endemic Alphacoronavirus that typically causes common cold-like disease in most healthy adults, but can also cause severe respiratory disease in the very young and the elderly. Althoug...
www.biorxiv.org
May 19, 2025 at 10:34 AM
Very excited to share our latest preprint describing the isolation and characterization of neutralizing HCoV-229E-directed antibodies from a human donor! Great collaboration between DHVI and the Baric and Sheahan (@timothysheahan.bsky.social) labs at UNC.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...