Alexander Mark Weber
@weberam2.bsky.social
Assistant Professor 🔍 in the Department of Pediatrics at UBC, Vancouver, Canada 🇨🇦
Interested in multi-model quantitative MRI 🧲 in developing baby brains 👶🧠.
Outdoor enthusiast 🧗🏂🚴🏻♂️🥾
weberlab.github.io
@weberam2@mastodon.social
Interested in multi-model quantitative MRI 🧲 in developing baby brains 👶🧠.
Outdoor enthusiast 🧗🏂🚴🏻♂️🥾
weberlab.github.io
@weberam2@mastodon.social
Pinned
Assessing Semiregional Cerebral Oxygen Consumption (CMRO2) in Preterm Neonates: A Quantitative MRI Cohort Study With Exploratory Analysis of Respiratory Support
This study presents a novel multimodal MRI approach to measure cerebral blood flow (CBF) and oxygen metabolism (CMRO2) in preterm infants. Exploratory findings suggest noninvasive respiratory support...
doi.org
🚨NEW PAPER OUT IN #NMRinBiomedicine🚨
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
Reposted by Alexander Mark Weber
A recent study led by Drs. @weberam2.bsky.social and Ruth Grunau explores an innovative way to measure how preterm infants’ brains use oxygen, using advanced MRI technology that is both safe and noninvasive.
Learn more about the work from UBC and @bcchresearch.bsky.social: https://bit.ly/46HAZ5m
Learn more about the work from UBC and @bcchresearch.bsky.social: https://bit.ly/46HAZ5m
October 10, 2025 at 5:16 PM
A recent study led by Drs. @weberam2.bsky.social and Ruth Grunau explores an innovative way to measure how preterm infants’ brains use oxygen, using advanced MRI technology that is both safe and noninvasive.
Learn more about the work from UBC and @bcchresearch.bsky.social: https://bit.ly/46HAZ5m
Learn more about the work from UBC and @bcchresearch.bsky.social: https://bit.ly/46HAZ5m
Very cool explanation of Markov Chains and how LLMs are just fancier versions of an old idea
elijahpotter.dev/articles/mar...
elijahpotter.dev/articles/mar...
Markov Chains Are the Original Language Models
Back in my day, we used math for autocomplete.
elijahpotter.dev
September 23, 2025 at 8:18 PM
Very cool explanation of Markov Chains and how LLMs are just fancier versions of an old idea
elijahpotter.dev/articles/mar...
elijahpotter.dev/articles/mar...
I am giving a talk next week about how to use your computer in a more efficient way: #homerowmods, copy/paste with #copyq, screenshots with #flameshot, #wezterm, #tmux, #zsh, #vim, #neovim, #windowtilingmanager, #bat, #eza, #fzf, #rg, #fd, #zoxide, #yazi or #vifm, #lazygit
Any other ideas?
Any other ideas?
September 18, 2025 at 5:25 PM
Big news! I was on a podcast for @bcchresearch.bsky.social
This was research in #preterm #brains, #oxygenation measured with #arterialspinlabelling and #qsm, and looking at ventilation methods.
Read more about the study here: bsky.app/profile/webe...
plmlex.clicks.mlsend.com/tl/c/eyJ2Ijo...
This was research in #preterm #brains, #oxygenation measured with #arterialspinlabelling and #qsm, and looking at ventilation methods.
Read more about the study here: bsky.app/profile/webe...
plmlex.clicks.mlsend.com/tl/c/eyJ2Ijo...
September 18, 2025 at 1:43 AM
Big news! I was on a podcast for @bcchresearch.bsky.social
This was research in #preterm #brains, #oxygenation measured with #arterialspinlabelling and #qsm, and looking at ventilation methods.
Read more about the study here: bsky.app/profile/webe...
plmlex.clicks.mlsend.com/tl/c/eyJ2Ijo...
This was research in #preterm #brains, #oxygenation measured with #arterialspinlabelling and #qsm, and looking at ventilation methods.
Read more about the study here: bsky.app/profile/webe...
plmlex.clicks.mlsend.com/tl/c/eyJ2Ijo...
Reposted by Alexander Mark Weber
New Open dataset alert:
🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience!
N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks!
🧵below
🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience!
N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks!
🧵below
September 4, 2025 at 7:21 PM
New Open dataset alert:
🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience!
N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks!
🧵below
🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience!
N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks!
🧵below
Publish or perish incentivises researchers to publish more, where scientific fraud has now become its own industry
www.science.org/content/arti...
www.science.org/content/arti...
Scientific fraud has become an ‘industry,’ alarming analysis finds | Science | AAAS
Sophisticated global networks are infiltrating journals to publish fake papers
www.science.org
August 5, 2025 at 9:02 PM
Publish or perish incentivises researchers to publish more, where scientific fraud has now become its own industry
www.science.org/content/arti...
www.science.org/content/arti...
My work is being highlighted by BCCHR Communications, but I don't use Facebook, Instagram or LinkedIn:
Facebook: www.facebook.com/share/p/1E3k...
Instagram: www.instagram.com/p/DMqKEWAp-G...
LinkedIn: www.linkedin.com/feed/update/...
Facebook: www.facebook.com/share/p/1E3k...
Instagram: www.instagram.com/p/DMqKEWAp-G...
LinkedIn: www.linkedin.com/feed/update/...
Redirecting...
www.facebook.com
July 28, 2025 at 11:20 PM
My work is being highlighted by BCCHR Communications, but I don't use Facebook, Instagram or LinkedIn:
Facebook: www.facebook.com/share/p/1E3k...
Instagram: www.instagram.com/p/DMqKEWAp-G...
LinkedIn: www.linkedin.com/feed/update/...
Facebook: www.facebook.com/share/p/1E3k...
Instagram: www.instagram.com/p/DMqKEWAp-G...
LinkedIn: www.linkedin.com/feed/update/...
Reposted by Alexander Mark Weber
Scientists overwhelmingly recognize the value of sharing null results, but rarely publish them in the research literature
go.nature.com/450KElr
go.nature.com/450KElr
Researchers value null results, but struggle to publish them
Survey finds that fear of reputational harm and a lack of support and publication platforms are among respondents’ key concerns.
go.nature.com
July 23, 2025 at 12:22 PM
Scientists overwhelmingly recognize the value of sharing null results, but rarely publish them in the research literature
go.nature.com/450KElr
go.nature.com/450KElr
Reposted by Alexander Mark Weber
I believe at this time we can afford more nuance and precision than this. Most null results are uninformative because most experiments are uninformative because we use NHST to replace the scientific process. We can't keep avoiding the root problem forever. Also the focus on efficiency is jarring.
Scientists overwhelmingly recognize the value of sharing null results, but rarely publish them in the research literature
go.nature.com/450KElr
go.nature.com/450KElr
Researchers value null results, but struggle to publish them
Survey finds that fear of reputational harm and a lack of support and publication platforms are among respondents’ key concerns.
go.nature.com
July 23, 2025 at 4:27 PM
I believe at this time we can afford more nuance and precision than this. Most null results are uninformative because most experiments are uninformative because we use NHST to replace the scientific process. We can't keep avoiding the root problem forever. Also the focus on efficiency is jarring.
Reposted by Alexander Mark Weber
Basic science is essential. "Most drugs don’t begin with research intended to make that drug. In fact, the results of their study showed that 80% of the medicines on their list led back to a discovery from basic research without any intention of creating a new drug" www.chronicle.com/article/in-d...
In Defense of ‘Silly’ Science
Basic research and the value of curiosity.
www.chronicle.com
June 24, 2025 at 12:55 PM
Basic science is essential. "Most drugs don’t begin with research intended to make that drug. In fact, the results of their study showed that 80% of the medicines on their list led back to a discovery from basic research without any intention of creating a new drug" www.chronicle.com/article/in-d...
Utterly fascinating
"Researchers using the same data
and hypothesis arrive at different
conclusions"
www.pnas.org/doi/10.1073/...
"Researchers using the same data
and hypothesis arrive at different
conclusions"
www.pnas.org/doi/10.1073/...
June 22, 2025 at 12:06 AM
Utterly fascinating
"Researchers using the same data
and hypothesis arrive at different
conclusions"
www.pnas.org/doi/10.1073/...
"Researchers using the same data
and hypothesis arrive at different
conclusions"
www.pnas.org/doi/10.1073/...
Reposted by Alexander Mark Weber
Pro tip, folks: if you make a figure for a publication, don’t just hand the copyright over to the publisher. Post it on OSF first and then give yourself permission to use it in the first publication and then all future publications. That way, no permissions issues.
June 10, 2025 at 7:59 PM
Pro tip, folks: if you make a figure for a publication, don’t just hand the copyright over to the publisher. Post it on OSF first and then give yourself permission to use it in the first publication and then all future publications. That way, no permissions issues.
Am I crazy, or did this paper get published with very low resolution figures?
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Developmental patterns of white matter functional networks in neonates
In recent years, the development of neonatal brain networks has become a research focus, with traditional studies primarily emphasizing gray matter (G…
www.sciencedirect.com
June 9, 2025 at 2:24 PM
Am I crazy, or did this paper get published with very low resolution figures?
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Alexander Mark Weber
This is breathtakingly shortsighted and just plain dumb
June 4, 2025 at 4:28 PM
This is breathtakingly shortsighted and just plain dumb
Excited to share my #biocommentary for @springernature.com in @pediatricresearch.bsky.social 📝✨ From #neuroscience at UofT 🧠 to discovering #MRI 🧲 at McMaster, then moving to BC to work with @rauschermri.bsky.social🏔️ My journey as an #assistantprofessor over the last 5 years! 👩🔬📚
rdcu.be/enUNo
rdcu.be/enUNo
ECI biocommentary
Pediatric Research - ECI biocommentary
rdcu.be
May 27, 2025 at 4:17 PM
Excited to share my #biocommentary for @springernature.com in @pediatricresearch.bsky.social 📝✨ From #neuroscience at UofT 🧠 to discovering #MRI 🧲 at McMaster, then moving to BC to work with @rauschermri.bsky.social🏔️ My journey as an #assistantprofessor over the last 5 years! 👩🔬📚
rdcu.be/enUNo
rdcu.be/enUNo
May 21, 2025 at 3:48 PM
🚨NEW PAPER OUT IN #NMRinBiomedicine🚨
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
Assessing Semiregional Cerebral Oxygen Consumption (CMRO2) in Preterm Neonates: A Quantitative MRI Cohort Study With Exploratory Analysis of Respiratory Support
This study presents a novel multimodal MRI approach to measure cerebral blood flow (CBF) and oxygen metabolism (CMRO2) in preterm infants. Exploratory findings suggest noninvasive respiratory support...
doi.org
May 20, 2025 at 9:47 PM
🚨NEW PAPER OUT IN #NMRinBiomedicine🚨
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
We developed a noninvasive MRI method to measure brain oxygen use (CMRO₂) and blood flow (CBF) in preterm infants. This could be key for understanding early brain development! #Neonatology #MRI #BrainHealth #openaccess 👶🧪
doi.org/10.1002/nbm....
🧵 1/9
Reposted by Alexander Mark Weber
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
May 13, 2025 at 7:55 PM
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.
Save and share the post!
Very cool review paper that cited our work
"studies suggest that neonatal metastability develops over the third gestational trimester, with ... greater signal complexity."
www.sciencedirect.com/science/arti...
the paper they cited: doi.org/10.1093/CERC...
"studies suggest that neonatal metastability develops over the third gestational trimester, with ... greater signal complexity."
www.sciencedirect.com/science/arti...
the paper they cited: doi.org/10.1093/CERC...
Development of brain metastable dynamics during the equivalent of the third gestational trimester
Metastability, a concept from dynamical systems theory, provides a framework for understanding how the brain shifts between various functional states …
www.sciencedirect.com
May 9, 2025 at 11:37 PM
Very cool review paper that cited our work
"studies suggest that neonatal metastability develops over the third gestational trimester, with ... greater signal complexity."
www.sciencedirect.com/science/arti...
the paper they cited: doi.org/10.1093/CERC...
"studies suggest that neonatal metastability develops over the third gestational trimester, with ... greater signal complexity."
www.sciencedirect.com/science/arti...
the paper they cited: doi.org/10.1093/CERC...
May 1, 2025 at 4:17 PM
May 1, 2025 at 4:17 PM
Reposted by Alexander Mark Weber
New paper in Imaging Neuroscience by Elodie Germani, Camille Maumet, et al:
On the validity of fMRI mega-analyses using data processed with different pipelines
doi.org/10.1162/imag...
On the validity of fMRI mega-analyses using data processed with different pipelines
doi.org/10.1162/imag...
May 1, 2025 at 2:42 PM
New paper in Imaging Neuroscience by Elodie Germani, Camille Maumet, et al:
On the validity of fMRI mega-analyses using data processed with different pipelines
doi.org/10.1162/imag...
On the validity of fMRI mega-analyses using data processed with different pipelines
doi.org/10.1162/imag...