Wagner Fagundes
@wagnercfagundes.bsky.social
Postdoc @ MPI for Biology - Langner's lab. Passionate about evolution in plant pathosystems | #beproud he/him
Reposted by Wagner Fagundes
Responses to Temperature Shocks in Zymoseptoria tritici Reveal Specific Transcriptional Reprogramming and Novel Candidate Genes for Thermal Adaptation | Phytopathology® apsjournals.apsnet.org/doi/full/10....
Responses to Temperature Shocks in Zymoseptoria tritici Reveal Specific Transcriptional Reprogramming and Novel Candidate Genes for Thermal Adaptation | Phytopathology®
Pathogens’ responses to sudden temperature fluctuations, spanning various temporal scales, are critical determinants of their survival, growth, reproduction, and homeostasis. Here, we combined phenoty...
apsjournals.apsnet.org
November 21, 2025 at 1:00 PM
Responses to Temperature Shocks in Zymoseptoria tritici Reveal Specific Transcriptional Reprogramming and Novel Candidate Genes for Thermal Adaptation | Phytopathology® apsjournals.apsnet.org/doi/full/10....
Reposted by Wagner Fagundes
TEs aren’t just genomic parasites, they’re also engines of genomic novelty.
Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.
With @danielcroll.bsky.social & @guidopuccetti.bsky.social
🧬 www.nature.com/articles/s41...
#TEworldwide
Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.
With @danielcroll.bsky.social & @guidopuccetti.bsky.social
🧬 www.nature.com/articles/s41...
#TEworldwide
Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
www.nature.com
November 12, 2025 at 1:17 PM
TEs aren’t just genomic parasites, they’re also engines of genomic novelty.
Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.
With @danielcroll.bsky.social & @guidopuccetti.bsky.social
🧬 www.nature.com/articles/s41...
#TEworldwide
Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.
With @danielcroll.bsky.social & @guidopuccetti.bsky.social
🧬 www.nature.com/articles/s41...
#TEworldwide
Reposted by Wagner Fagundes
Postdoc position available at Max Planck Institute, Germany, focusing on the genetic basis of polygenic traits in Drosophila. Applications due by Dec 22, 2025. More info: barghi@evolbio.mpg.de. #postdoc
November 11, 2025 at 4:44 PM
Postdoc position available at Max Planck Institute, Germany, focusing on the genetic basis of polygenic traits in Drosophila. Applications due by Dec 22, 2025. More info: barghi@evolbio.mpg.de. #postdoc
Reposted by Wagner Fagundes
Do you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp....
genzplyr is dplyr, but bussin fr fr no cap.
genzplyr is dplyr, but bussin fr fr no cap.
GitHub - hadley/genzplyr: dplyr but make it bussin fr fr no cap
dplyr but make it bussin fr fr no cap. Contribute to hadley/genzplyr development by creating an account on GitHub.
github.com
November 6, 2025 at 11:25 PM
Do you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp....
genzplyr is dplyr, but bussin fr fr no cap.
genzplyr is dplyr, but bussin fr fr no cap.
Reposted by Wagner Fagundes
1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start?
We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!
www.biorxiv.org/content/10.1...
We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!
www.biorxiv.org/content/10.1...
October 29, 2025 at 9:02 AM
1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start?
We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!
www.biorxiv.org/content/10.1...
We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!
www.biorxiv.org/content/10.1...
Reposted by Wagner Fagundes
📣 I’m excited to share two open positions in my lab @leibniz-hki.de. For this interdisciplinary project with @luziagyr.bsky.social, I’m seeking (1) an enthusiastic PhD student interested in fungal natural product research and genetic engineering, as well as (2) a technical assistant 👇🏻
October 21, 2025 at 2:48 PM
📣 I’m excited to share two open positions in my lab @leibniz-hki.de. For this interdisciplinary project with @luziagyr.bsky.social, I’m seeking (1) an enthusiastic PhD student interested in fungal natural product research and genetic engineering, as well as (2) a technical assistant 👇🏻
Reposted by Wagner Fagundes
Fungal #GenomeSize variation is largely driven by TEs & lineage-specific genome defenses. @tbadet.bsky.social & @danielcroll.bsky.social show that presence/absence of RIP mutation systems influences #genome architecture, identifying a likely novel defense mechanism @plosbiology.org 🧪 plos.io/4hcC5tx
October 16, 2025 at 7:58 AM
Fungal #GenomeSize variation is largely driven by TEs & lineage-specific genome defenses. @tbadet.bsky.social & @danielcroll.bsky.social show that presence/absence of RIP mutation systems influences #genome architecture, identifying a likely novel defense mechanism @plosbiology.org 🧪 plos.io/4hcC5tx
Reposted by Wagner Fagundes
Tracking the evolutionary trajectory of a young hybrid plant pathogen. New preprint on how triticale powdery mildew evolved in the ~25 years since its emergence. Congrats to @jigisha1.bsky.social and all coauthors! doi.org/10.1101/2025...
Tracking the evolutionary trajectory of a young hybrid plant pathogen
A common mechanism by which emerging plant pathogens gain the ability to infect new hosts is hybridization. Despite its widespread occurrence, the outcomes of hybridization remain largely unpredictabl...
doi.org
October 13, 2025 at 6:47 AM
Tracking the evolutionary trajectory of a young hybrid plant pathogen. New preprint on how triticale powdery mildew evolved in the ~25 years since its emergence. Congrats to @jigisha1.bsky.social and all coauthors! doi.org/10.1101/2025...
Reposted by Wagner Fagundes
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
www.berufungen.uni-kiel.de
October 12, 2025 at 9:01 AM
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
Reposted by Wagner Fagundes
So happy to see my first first-author paper published! 🎈
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
Characterization of the transposable element landscape shaping the Ectocarpus genome | Genome Biology
rdcu.be
October 1, 2025 at 8:12 AM
So happy to see my first first-author paper published! 🎈
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
A short thread on how Ectocarpus and its TE secrets have kept me busy lately:
rdcu.be/eITQH
Reposted by Wagner Fagundes
I’m super happy to present the first discoveries of the RIKEN-Cambridge Joint Crop Symbiosis Research Team, based in Japan 🇯🇵
doi.org/10.1101/2025...
A thread 👇
doi.org/10.1101/2025...
A thread 👇
Reductive evolution of the DNA replication machinery in endosymbiotic fungi
The molecular machinery for replicating and repairing DNA accurately is critically important for life and highly conserved across the Tree of Life. Here we show that two major lineages of fungi, Glome...
doi.org
September 3, 2025 at 3:21 PM
I’m super happy to present the first discoveries of the RIKEN-Cambridge Joint Crop Symbiosis Research Team, based in Japan 🇯🇵
doi.org/10.1101/2025...
A thread 👇
doi.org/10.1101/2025...
A thread 👇
Reposted by Wagner Fagundes
Delighted that our work on the Sanctuary Starship #transposon is now published! A big thanks to all co-authors, especially to the ever-amazing @mcdonaldmeganc.bsky.social for her mentorship!
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
Sanctuary: a Starship transposon facilitating the movement of the virulence factor ToxA in fungal wheat pathogens | mBio
The work presented here expands our understanding of a novel group of mobile genetic
elements called Starships that facilitate the horizontal exchange of numerous genes between fungal pathogens.
Our a...
doi.org
September 6, 2025 at 1:11 PM
Delighted that our work on the Sanctuary Starship #transposon is now published! A big thanks to all co-authors, especially to the ever-amazing @mcdonaldmeganc.bsky.social for her mentorship!
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
Reposted by Wagner Fagundes
How diverse are the individual strains within your species?
How broad is their Pangenome?
How will you choose representatives from the whole collection?
Look no further! PanGene-O-Meter is here for you!
From @haimashkenazy.bsky.social @plantevolution.bsky.social
www.biorxiv.org/content/10.1...
How broad is their Pangenome?
How will you choose representatives from the whole collection?
Look no further! PanGene-O-Meter is here for you!
From @haimashkenazy.bsky.social @plantevolution.bsky.social
www.biorxiv.org/content/10.1...
PanGene-O-Meter: Intra-Species Diversity Based on Gene-Content
Bacterial genome evolution is shaped to a great extent by horizontal gene transfer, detectable as genes with a presence-absence pattern of variation that does not follow phylogenetic relationships acr...
www.biorxiv.org
September 2, 2025 at 7:20 AM
How diverse are the individual strains within your species?
How broad is their Pangenome?
How will you choose representatives from the whole collection?
Look no further! PanGene-O-Meter is here for you!
From @haimashkenazy.bsky.social @plantevolution.bsky.social
www.biorxiv.org/content/10.1...
How broad is their Pangenome?
How will you choose representatives from the whole collection?
Look no further! PanGene-O-Meter is here for you!
From @haimashkenazy.bsky.social @plantevolution.bsky.social
www.biorxiv.org/content/10.1...
Reposted by Wagner Fagundes
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
September 1, 2025 at 8:46 AM
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
Reposted by Wagner Fagundes
Joint #CallForProposals! Within the scope of their Cooperation Agreement, the Brazilian @cnpq-oficial.bsky.social and the DFG are pleased to announce a joint call for German-Brazilian research projects in the fields of agricultural sciences, forestry and veterinary medicine.
Details:
fcld.ly/ifdw69
Details:
fcld.ly/ifdw69
DFG-CNPq: Brazilian-German Joint Call for Proposals in the Fields of Agricultural Sciences, Forestry and Veterinary Medicine
fcld.ly
August 25, 2025 at 2:29 PM
Joint #CallForProposals! Within the scope of their Cooperation Agreement, the Brazilian @cnpq-oficial.bsky.social and the DFG are pleased to announce a joint call for German-Brazilian research projects in the fields of agricultural sciences, forestry and veterinary medicine.
Details:
fcld.ly/ifdw69
Details:
fcld.ly/ifdw69
Reposted by Wagner Fagundes
Really happy this is out in preprint - Congratulations to @graemekettles.bsky.social @zymohaider.bsky.social, and everyone involved for their hard work completing this study! It examines a Z. tritici effector that is a molecular mimic of plant LRRs, and suppresses PTI www.biorxiv.org/content/10.1...
Molecular mimicry of plant cell-surface immune receptors by fungal secreted leucine-rich repeat proteins
Leucine-rich repeat (LRR) receptor-like kinases (LRR-RLKs) are important plant immunity proteins. The wheat pathogen Zymoseptoria tritici produces many virulence effectors during infection; however, m...
www.biorxiv.org
August 24, 2025 at 8:35 PM
Really happy this is out in preprint - Congratulations to @graemekettles.bsky.social @zymohaider.bsky.social, and everyone involved for their hard work completing this study! It examines a Z. tritici effector that is a molecular mimic of plant LRRs, and suppresses PTI www.biorxiv.org/content/10.1...
Reposted by Wagner Fagundes
Transposable elements in brown algae? 🌊
Yes, they’re full of surprises ✨
Come meet Ectocarpus at #ESEB2025!
📍Room 113 - S28.03
🗓️ Thursday, 2:30pm
Yes, they’re full of surprises ✨
Come meet Ectocarpus at #ESEB2025!
📍Room 113 - S28.03
🗓️ Thursday, 2:30pm
August 19, 2025 at 11:22 AM
Transposable elements in brown algae? 🌊
Yes, they’re full of surprises ✨
Come meet Ectocarpus at #ESEB2025!
📍Room 113 - S28.03
🗓️ Thursday, 2:30pm
Yes, they’re full of surprises ✨
Come meet Ectocarpus at #ESEB2025!
📍Room 113 - S28.03
🗓️ Thursday, 2:30pm
Reposted by Wagner Fagundes
📣 NEW PREPRINT 📝
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
www.biorxiv.org
August 15, 2025 at 7:47 AM
📣 NEW PREPRINT 📝
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc @teamthomma.bsky.social
Reposted by Wagner Fagundes
Happy to be able to finally share our NLR pangenome paper, out now in CHM.
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
Pangenomic context reveals the extent of intraspecific plant NLR evolution
Individual- and population-level diversity is required for pathogen defense by nucleotide-binding
site leucine-rich repeat (NLR) proteins. Teasdale et al. leverage annotated, divergent
A. thaliana gen...
www.cell.com
August 14, 2025 at 5:55 AM
Happy to be able to finally share our NLR pangenome paper, out now in CHM.
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
"Pangenomic context reveals the extent of intraspecific plant NLR evolution"
www.cell.com/cell-host-mi...
#plantscience #plantimmunity #pangenomes #science #nlr
Reposted by Wagner Fagundes
We’re excited to share our latest work on plant pathogen effector protein evolution @biorxivpreprint.bsky.social. With @kamounlab.bsky.social and Abbas Maqbool.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Rewinding the tape: historical contingency and functional constraints have shaped the evolution of APikL virulence effectors in the blast fungus
Protein evolution is influenced by historical contingencies and functional constraints, but their combined impact on rapidly diversifying pathogen virulence effectors remains poorly understood. Here, ...
www.biorxiv.org
August 13, 2025 at 2:36 PM
We’re excited to share our latest work on plant pathogen effector protein evolution @biorxivpreprint.bsky.social. With @kamounlab.bsky.social and Abbas Maqbool.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Wagner Fagundes
1/ Excited to share our latest opinion piece published today in Trends in Microbiology (@cp-trendsmicrobiol.bsky.social):
Hypermutator fungal pathogens: from threat to meltdown
Here, we argue that the origin of hypermutation follows defined principles, rather than...
Hypermutator fungal pathogens: from threat to meltdown
Here, we argue that the origin of hypermutation follows defined principles, rather than...
August 7, 2025 at 8:05 AM
1/ Excited to share our latest opinion piece published today in Trends in Microbiology (@cp-trendsmicrobiol.bsky.social):
Hypermutator fungal pathogens: from threat to meltdown
Here, we argue that the origin of hypermutation follows defined principles, rather than...
Hypermutator fungal pathogens: from threat to meltdown
Here, we argue that the origin of hypermutation follows defined principles, rather than...
Reposted by Wagner Fagundes
📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp
rdcu.be/exBSp
Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution
Nature Communications - Giant transposons, known as ‘Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions...
rdcu.be
July 24, 2025 at 10:40 AM
📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp
rdcu.be/exBSp
Reposted by Wagner Fagundes
#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today!
From 13:30 to 15:15 🌾
From 13:30 to 15:15 🌾
July 17, 2025 at 7:27 AM
#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today!
From 13:30 to 15:15 🌾
From 13:30 to 15:15 🌾
Reposted by Wagner Fagundes
📣 I’m recruiting a #Postdoc to help us further our understanding on the infection strategies of our human fungal pathogen. If you’re enthusiastic about research, our interdisciplinary group @leibniz-hki.de will be a good fit for you! Please share!
jobs.hki-jena.de/jobs/Postdoc...
jobs.hki-jena.de/jobs/Postdoc...
Job opportunity Postdoctoral Researcher (m/w/div) in “Microbial Infection Strategies” at Leibniz HKI Jobportal
Wissenschaft/Forschung in Jena
jobs.hki-jena.de
July 17, 2025 at 5:41 AM
📣 I’m recruiting a #Postdoc to help us further our understanding on the infection strategies of our human fungal pathogen. If you’re enthusiastic about research, our interdisciplinary group @leibniz-hki.de will be a good fit for you! Please share!
jobs.hki-jena.de/jobs/Postdoc...
jobs.hki-jena.de/jobs/Postdoc...
Reposted by Wagner Fagundes
What makes wild wheat resistant to domestic Zymoseptoria?
Our PhD student Rune Hansen found wild wheat relatives that stop infection by domestic Zymoseptoria at the stomata, with a pool of candidate genes that could potentially boost resistance in domestic wheat.
🗓️ Poster P-015
#2025ISMPMI
Our PhD student Rune Hansen found wild wheat relatives that stop infection by domestic Zymoseptoria at the stomata, with a pool of candidate genes that could potentially boost resistance in domestic wheat.
🗓️ Poster P-015
#2025ISMPMI
July 16, 2025 at 8:42 AM
What makes wild wheat resistant to domestic Zymoseptoria?
Our PhD student Rune Hansen found wild wheat relatives that stop infection by domestic Zymoseptoria at the stomata, with a pool of candidate genes that could potentially boost resistance in domestic wheat.
🗓️ Poster P-015
#2025ISMPMI
Our PhD student Rune Hansen found wild wheat relatives that stop infection by domestic Zymoseptoria at the stomata, with a pool of candidate genes that could potentially boost resistance in domestic wheat.
🗓️ Poster P-015
#2025ISMPMI