Valentina Lo Sardo
@valels.bsky.social
Assistant Professor at University of Wisconsin-Madison SMPH, Cell and Regenerative Biology Department. Stem cell-based functional genomics of cardiovascular disease. Opinions are my own.
Wonderful meeting @aegeanstemcells.bsky.social! An incredible lineup of speakers and spectacular science. Thanks to our own Jeff @epigeneticsmsn.bsky.social for organizing this event. What could be better than having @uwmadscience.bsky.social CRB delegation in sunny Crete? @blanclab.bsky.social
October 6, 2025 at 8:38 AM
Wonderful meeting @aegeanstemcells.bsky.social! An incredible lineup of speakers and spectacular science. Thanks to our own Jeff @epigeneticsmsn.bsky.social for organizing this event. What could be better than having @uwmadscience.bsky.social CRB delegation in sunny Crete? @blanclab.bsky.social
Thanks to the UW-Madison Stem Cell and Regenerative Medicine Center for highlighting our recent work!!🫀🧫🔬
stemcells.wisc.edu/2025/06/04/u...
stemcells.wisc.edu/2025/06/04/u...
UW–Madison researchers find hidden clues in a decades-old mystery surrounding cardiovascular disease
Researchers at the University of Wisconsin–Madison have uncovered new evidence in a decades-old genetic mystery, discovering how multiple genetic variations in a long-mysterious region of the human ge...
stemcells.wisc.edu
June 5, 2025 at 4:02 PM
Thanks to the UW-Madison Stem Cell and Regenerative Medicine Center for highlighting our recent work!!🫀🧫🔬
stemcells.wisc.edu/2025/06/04/u...
stemcells.wisc.edu/2025/06/04/u...
If you are passionate about stem cells consider coming to Greece for a wonderful lineup of speakers, a lot of networking and amazing science!! Check the website for early registration and travel awards!
🔬 6th International Aegean Conference on Stem Cells 📢
Join us Oct 1–6, 2025 in Crete, for talks on stem cell biology, regenerative medicine, genome editing & aging.
📅 Abstracts & Early Reg: Due June 1, 2025
🔗 Register now: www.aegeanconferences.org/src/App/conf...
#AegeanStemCells2025 #StemCells
Join us Oct 1–6, 2025 in Crete, for talks on stem cell biology, regenerative medicine, genome editing & aging.
📅 Abstracts & Early Reg: Due June 1, 2025
🔗 Register now: www.aegeanconferences.org/src/App/conf...
#AegeanStemCells2025 #StemCells
May 22, 2025 at 2:43 AM
If you are passionate about stem cells consider coming to Greece for a wonderful lineup of speakers, a lot of networking and amazing science!! Check the website for early registration and travel awards!
Ready for the next three days of great science #VascularDiscovery25
April 22, 2025 at 8:33 PM
Ready for the next three days of great science #VascularDiscovery25
CXCL12 drives natural variation in coronary artery anatomy across diverse populations: Cell www.cell.com/cell/fulltex...
CXCL12 drives natural variation in coronary artery anatomy across diverse populations
Coronary dominance is a clinically important developmental phenotype that dictates
whether the left or right coronary arteries perfuse the back of the heart. Genome-wide
association studies and downst...
www.cell.com
April 3, 2025 at 6:13 PM
CXCL12 drives natural variation in coronary artery anatomy across diverse populations: Cell www.cell.com/cell/fulltex...
Thrilled to share the🥇paper from the lab @ahajournals.bsky.social. Here we continue to unravel the mysteries of the 9p21.3 CAD locus showing it drives VSMC transition into an osteochondrogenic state, promoting calcification. @clintomics.bsky.social @UWMadison CRB.
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Genome-wide association studies have identified common genetic variants at ≈300 human
genomic loci linked to coronary artery disease susceptibility. Among these genomic
regions, the most i...
www.ahajournals.org
March 30, 2025 at 8:15 PM
Thrilled to share the🥇paper from the lab @ahajournals.bsky.social. Here we continue to unravel the mysteries of the 9p21.3 CAD locus showing it drives VSMC transition into an osteochondrogenic state, promoting calcification. @clintomics.bsky.social @UWMadison CRB.
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Congrats to @andreagalmozzi.bsky.social lab for this great study just out in @natmetabolism.bsky.social!! I’m a proud colleague, partner and wife!! ❤️❤️❤️
Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social
Excited to share that work from my PhD is now available in @natmetabolism.bsky.social! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D.
Link to paper: urldefense.com/v3/__https:/...
A Thread (1/15)
Link to paper: urldefense.com/v3/__https:/...
A Thread (1/15)
March 25, 2025 at 4:19 PM
Congrats to @andreagalmozzi.bsky.social lab for this great study just out in @natmetabolism.bsky.social!! I’m a proud colleague, partner and wife!! ❤️❤️❤️
Reposted by Valentina Lo Sardo
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
Reposted by Valentina Lo Sardo
A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
A foundation model of transcription across human cell types - Nature
A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...
www.nature.com
January 8, 2025 at 4:27 PM
A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
🤩❤️ Beautiful atlas of vascular cells in the human body! www.nature.com/articles/s41...
An organotypic atlas of human vascular cells - Nature Medicine
A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.
www.nature.com
December 14, 2024 at 1:56 PM
🤩❤️ Beautiful atlas of vascular cells in the human body! www.nature.com/articles/s41...