Dylan Duerre
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dylanduerre.bsky.social
Dylan Duerre
@dylanduerre.bsky.social
32 followers 27 following 16 posts
PhD candidate in the Galmozzi Lab at UW-Madison. 🔬 scientist 🧬, 🏔️ wilderness advocate 🌲, 🥅 hockey fan 🏒.
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dylanduerre.bsky.social
I am excited to share that one week from today, I will defend my doctoral thesis and complete my PhD training at UW-Madison.

This presentation will be public and is designed to be accessible to everyone. If you are interested in attending, reach out and I will send a Zoom link!
June 16, 2025 at 4:06 PM
Reposted by Dylan Duerre
andreagalmozzi.bsky.social
Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social
March 25, 2025 at 2:41 PM
Reposted by Dylan Duerre
natmetabolism.nature.com
A BCAA–haem axis regulates brown fat function
Nature Metabolism, Published online: 25 March 2025; doi:10.1038/s42255-025-01266-1Activated brown adipose tissue takes up large amounts of branched-chain amino acids (BCAAs), but their fate remains unclear. We provide evidence of a metabolic link between BCAA catabolism and haem biosynthesis, which supports mitochondrial function and regulates gene expression by influencing the epigenetic landscape of brown adipocytes.
bit.ly
March 26, 2025 at 1:03 AM
Reposted by Dylan Duerre
natmetabolism.nature.com
Haem biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue
Nature Metabolism, Published online: 25 March 2025; doi:10.1038/s42255-025-01253-6Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which reduces UCP1 levels and impairs thermogenesis.
bit.ly
March 26, 2025 at 1:03 AM
dylanduerre.bsky.social
Excited to share that work from my PhD is now available in @natmetabolism.bsky.social! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D.

Link to paper: urldefense.com/v3/__https:/...

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Haem biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue
Nature Metabolism - Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which reduces UCP1 levels and impairs...
urldefense.com
March 25, 2025 at 2:06 PM