Ule Lab
@ulelab.bsky.social
Welcome to the RNA networks lab! At the UK DRI at King's College London, Francis Crick Institute and Kemijski inštitut (National Institute of Chemistry) in Ljubljana 🇪🇺
A great read! link.springer.com/article/10.1...
What is the question? - Genome Biology
Genome Biology -
link.springer.com
January 24, 2026 at 9:30 AM
A great read! link.springer.com/article/10.1...
Congrats Iosifina and Paulo, great team work!
This research was led by Iosifina Foskolou and Paulo Gameiro (Universidade Nova de Lisboa), with corresponding authors Jernej Ule (@ulelab.bsky.social) and Randall Johnson (@ki.se).
January 24, 2026 at 9:29 AM
Congrats Iosifina and Paulo, great team work!
Reposted by Ule Lab
www.nature.com/articles/s41...
Polyamines in the regulation of splicing (and potentially transciption dynamics)
From Carracedo lab.
Really cool to see this.
Time to figure out polyamines control molecular homeostasis, especially in the context of aging
Polyamines in the regulation of splicing (and potentially transciption dynamics)
From Carracedo lab.
Really cool to see this.
Time to figure out polyamines control molecular homeostasis, especially in the context of aging
Polyamine-dependent metabolic shielding regulates alternative splicing - Nature
Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.
www.nature.com
January 24, 2026 at 7:08 AM
www.nature.com/articles/s41...
Polyamines in the regulation of splicing (and potentially transciption dynamics)
From Carracedo lab.
Really cool to see this.
Time to figure out polyamines control molecular homeostasis, especially in the context of aging
Polyamines in the regulation of splicing (and potentially transciption dynamics)
From Carracedo lab.
Really cool to see this.
Time to figure out polyamines control molecular homeostasis, especially in the context of aging
Reposted by Ule Lab
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
November 21, 2025 at 5:37 PM
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
Collective challenges need collective solutions. Happy to share the insights we've gained from the way our cells handle this: www.nature.com/articles/s41... and its summary www.crick.ac.uk/news/2025-09....
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
September 24, 2025 at 4:25 PM
Collective challenges need collective solutions. Happy to share the insights we've gained from the way our cells handle this: www.nature.com/articles/s41... and its summary www.crick.ac.uk/news/2025-09....
Very pleased to share this new preprint from our group, uncovering how alternative polyadenylation is regulated by arginine methylation: PRMT activity promotes global 3’ UTR shortening in proliferating cells www.biorxiv.org/content/10.1...
PRMT activity promotes global 3’ UTR shortening in proliferating cells
Protein methyltransferase (PRMT)-catalysed arginine methylation is a widespread post-translational modification that regulates numerous RNA-binding proteins and frequently becomes dysregulated in canc...
www.biorxiv.org
March 19, 2025 at 10:31 AM
Very pleased to share this new preprint from our group, uncovering how alternative polyadenylation is regulated by arginine methylation: PRMT activity promotes global 3’ UTR shortening in proliferating cells www.biorxiv.org/content/10.1...
Reposted by Ule Lab
Carlos Santana (UPenn) argues that optimal openness is not maximum openness. Openness is one of the core values that govern science. Trade offs apply depending on contexts. #ScienceAndValues #philsci #philsky
The Value of Openness in Open Science | Canadian Journal of Philosophy | Cambridge Core
The Value of Openness in Open Science
www.cambridge.org
December 22, 2024 at 1:32 PM
Carlos Santana (UPenn) argues that optimal openness is not maximum openness. Openness is one of the core values that govern science. Trade offs apply depending on contexts. #ScienceAndValues #philsci #philsky