Sanford Stem Cell Institute UC San Diego
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Sanford Stem Cell Institute UC San Diego
@ucsdstemcells.bsky.social
The UC San Diego Sanford Stem Cell Institute is a global hub for stem cell science and innovation, advancing research in space & through active clinical trials.
🧬 The research of our Ludmil Alexandrov, PhD, is highlighted in a recent @businessinsider.com piece on rising rates of aggressive colon #cancer in otherwise healthy young adults. One potential contributor, according to Alexandrov: childhood E. coli infection. 🦠 Read the full piece @ bit.ly/49JBqxp.
What causes early-onset colon cancer? New research offers clues
Doctors are seeing colon cancer in people in their 20s and 30s. New research suggests it starts in infancy.
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January 8, 2026 at 10:09 PM
🙌 A $7.4 million California Institute for Regenerative Medicine grant awarded to SSCI expert Stephanie Cherqui, PhD, and team will ready a revolutionary new treatment — a stem cell-based gene therapy for Friedreich’s ataxia — for clinical trial. 🎉 More: bit.ly/4jw1qiY. H/t @cirmnews.bsky.social
January 8, 2026 at 6:12 PM
🦠 Last year saw fascinating developments in cell biology. 👀 Among those capturing the most public interest at The Scientist: SSCI Director Catriona Jamieson’s research on stem cell aging in space. 🛰️ Read more about her impactful work at bit.ly/4qamL4n. 🧫
Top Cell Biology Stories of 2025
Find out which cell biology stories grabbed the most interest this last year.
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January 6, 2026 at 6:31 PM
🎧 Tune in for our reGEN Podcast episode with Marisa Korody, PhD, as we discuss conservation genetics at the @sandiegozoo.bsky.social. Her team's groundbreaking work uses #stemcells to help save the northern white rhino 🦏 from extinction. Watch bit.ly/4pUe7H2 or listen where you get your podcasts.
Conservation Genetics at the San Diego Zoo Wildlife Alliance | Marisa Korody, PhD
Marisa Korody, PhD, serves San Diego Zoo Wildlife Alliance as a scientist in conservation genetics, working on the northern white rhino rescue project. She works closely with collaborators at The Scripps Research Institute to optimize the production of induced pluripotent stem cells (iPSCs) from banked rhino fibroblast cells in the Frozen Zoo® for potential use in assisted reproductive technologies. This episode was recorded on Aug. 13, 2025, and information is current as of the date of recording. Hosted by Bobby Gordon.
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December 24, 2025 at 5:08 PM
🌍 International research collaborations help avoid duplication of effort, speed progress and spread new knowledge. Our recent Hertzberg-Schechter Stem Cell Workshop did just that, uniting U.S. experts with those from Israel’s Weizmann Institute of Science. More @ bit.ly/4p5uEGV. 🔬
December 23, 2025 at 8:39 PM
Best. Present. Ever! 🎁 A toddler born with a deadly rare genetic disorder who received a personalized gene therapy earlier this year thanks to our Alexis Komor, PhD, et al., is home from the hospital and walking — just in time for the holidays! 🥳
KJ Muldoon, at less than a year old, was the first known person to receive a personalised CRISPR-based genome-editing therapy

He is part of Nature’s 10, a list of people who shaped science in 2025

go.nature.com/4j1uI95
The baby whose life was saved by the first personalized CRISPR therapy
Nature - KJ Muldoon is part of Nature’s 10, a list of people who shaped science in 2025.
go.nature.com
December 22, 2025 at 10:25 PM
🔬 Chromosome-shattering is one reason some #cancer cells evolve rapidly & resist treatment. For 15 years, the cause was unknown. Our Frank Furnari, PhD, & Ludmil Alexandrov, PhD, as well as other @ucsandiego.bsky.social researchers, solve the mystery this month in @science.org: bit.ly/4paoNA1
Scientists Uncover Key Driver of Treatment-Resistant Cancer
UC San Diego scientists have identified the enzyme that shatters cancer genomes and helps them evolve to resist treatment, solving a longstanding mystery in the molecular biology of cancer.
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December 22, 2025 at 5:53 PM
🎉 Did you know? SSCI’s Alysson Muotri & Stephanie Cherqui co-direct the Gene Therapy Initiative at @ucsandiego.bsky.social, which has helped fund the work of our Dan Kaufman & @geneyeo.bsky.social. It all started 2 decades ago w/the birthday wish of a girl w/a rare disorder. 🎂 More: bit.ly/4aswL3X
From Wish to Reality — The Gene Therapy Initiative at UC San Diego
A young patient’s wish sparks a decades long partnership that leads UC San Diego to pioneer life changing gene therapies, transforming cystinosis care and advancing treatments for many diseases.
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December 18, 2025 at 6:10 PM
👏 We're proud to announce that SSCI’s Ludmil B. Alexandrov and team are recipients of Curebound's $1 Million Cure Prize for their work to detect pancreatic #cancer early. Major congrats to @signerlab.bsky.social and Frank Furnari, too, for receiving Discovery grants. More @ bit.ly/44RFedp
December 17, 2025 at 5:44 PM
👩‍🚀 What are the health effects of space on astronauts? Our Catriona Jamieson, MD, PhD, sheds light on the topic in a new @cp-cellstemcell.bsky.social article. Her work — the 1st comprehensive study of stem cell health in astronauts — provides answers NASA Twins couldn't: bit.ly/3KsuyLe
December 4, 2025 at 9:42 PM
Alysson Muotri, PhD, was recently featured in The Telegraph: “Space can accelerate the senescence of human brain cells, compressing the research time,” and he thinks it's “very likely” that a cure for motor neurone disease may be found by research in space bit.ly/43ALEgg
Astronauts working on cure for motor neurone disease from space
Radiation and lack of gravity help scientists research brain disease as cells prematurely age in the orbiting laboratories
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November 19, 2025 at 4:56 PM
The 2025 UC San Diego Sanford Stem Cell Institute symposium brought together over 700 extraordinary scientists, clinicians, innovators and patients united by a shared vision: harnessing the power of stem cells to heal, regenerate and transform medicine. bit.ly/4hKs9rn
Stem Cells, Space and the Future of Regenerative Medicine: Inside the 2025 SSCI Symposium
The 2025 Sanford Stem Cell Institute (SSCI) symposium at UC San Diego brought together an extraordinary group of scientists, clinicians, innovators and patients united by a shared vision: harnessing t...
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November 5, 2025 at 9:55 PM
Reposted by Sanford Stem Cell Institute UC San Diego
The 2025 @ucsdstemcells.bsky.social symposium at @UCSanDiego.bsky.social brought together an extraordinary group of #scientists, #clinicians, #innovators and #patients united by a shared vision: harnessing the power of #stemcells to heal, regenerate and transform #medicine.

buff.ly/mrK9GM1
Stem Cells, Space and the Future of Regenerative Medicine: Inside the 2025 SSCI Symposium
The 2025 Sanford Stem Cell Institute (SSCI) symposium at UC San Diego brought together an extraordinary group of scientists, clinicians, innovators and patients united by a shared vision: harnessing…
today.ucsd.edu
November 5, 2025 at 7:27 PM
Congratulations to Alexis Komor, PhD, for being honored with the 2025 Advanced Science Young Innovator Award. Komor is working to develop new precision genome editing methodologies to functionally interrogate how specific point mutations contribute to human disease. #stemcells #CRISPR bit.ly/49cBtly
October 23, 2025 at 6:04 PM
Watch our latest reGEN Podcast conversation with Alexander Khalessi, MD, MBA as we discuss innovations in stem cell therapies and neurological disorders. Listen and subscribe on wherever you find your podcasts. #stemcells #neurological #UCSD #UCSanDiego bit.ly/3Jm4Lnj
Alex Khalessi, MD, MBA | Stem Cell Therapy and Neurological Disorders
Our discussion in this episode features Alex Khalessi, MD, MBA, and his innovative work on the intersection between stem cell therapies, regenerative medicine, and neurological disorders. He serves as co-director of the Brain Tumor and Neurorestoration Program at the Sanford Stem Cell Institute. Khalessi is the current president of the Congress of Neurological Surgeons (CNS), and is chair of the Department of Neurological Surgery, professor of neurological surgery, radiology and neurosciences and the inaugural Don and Karen Cohn Chancellor’s Endowed Chair in Neurosurgery at UC San Diego. As a board-certified neurosurgeon, he specializes in complex cranial surgery, endovascular neurosurgery, stroke care, and neurological oncology. Hosted by Bobby Gordon. This episode was recorded Aug. 15, 2025; information presented was current as of the date of recording.
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October 22, 2025 at 10:42 PM
We hosted local high school students this week in our labs and facilities for our annual Stem Cell Awareness Day. Thank you Fox 5 San Diego for the feature story! www.youtube.com/watch?v=zmvf... #stemcells #STEM #UCSD #UCSanDiego
100 high school students attend UCSD STEM event
YouTube video by FOX 5 San Diego
www.youtube.com
October 9, 2025 at 9:54 PM
Fred “Rusty” Gage, PhD, with the @salkinstitute.bsky.social presents “Neural Stem Cells” at our annual symposium on Oct. 16, 9:05 a.m. PT. Register to watch his keynote online at bit.ly/4n1D5m9. #stemcells #brain #UCSD #UCSanDiego
October 8, 2025 at 8:57 PM
Join us for the “Stem Cell Biology, Development and Aging” keynote from Juan Carlos Izpisua Belmonte, PhD, on Oct. 17, 9:15 a.m. PT. His work at @altoslabs.bsky.social includes developing therapeutics to overcome disease and aging. Register to join online for our annual symposium bit.ly/4n1D5m9.
October 7, 2025 at 9:14 PM
Tune in online as Andreas Trumpp, PhD shares his keynote “Cancer Stem Cells” on Friday, Oct. 17, at 3:25 p.m. Trumpp is the managing director of the German Cancer Research Center. Online virtual registration is still open for our annual symposium at bit.ly/4n1D5m9. #stemcells #cancer #UCSD
October 6, 2025 at 9:00 PM
👩🏻‍🔬 @columbiauniversity.bsky.social's Tannishtha Reya, PhD, is known for being part of a team that coined the term "cancer stem cell" in @Nature in 2001. Hear her speak on stem cells & precancer 4:35 – 5:40 p.m. PT Thursday, Oct. 16, @ our annual symposium! Get no-cost virtual tix @ bit.ly/4n1D5m9. 🧫
October 3, 2025 at 7:16 PM
👩🏼‍🚀 We’re excited to announce the addition of retired NASA astronaut Kate Rubins, a microbiologist in the U.S. Army Reserve, to our 2025 symposium lineup. She’ll speak at a fireside chat Oct. 16, 2:05–3:05 p.m. PT — and you can listen in! Register for your no-cost virtual tickets at bit.ly/4n1D5m9. ☄️
October 2, 2025 at 5:35 PM
🎧 Watch our latest reGEN Podcast episode with Pinar Mesci, PhD, MSc from Axiom Space, "Innovative Stem Cell Research in Space." 🚀 bit.ly/42l9Ane You can find our podcast on YouTube 📺 and major podcast platforms.
Pinar Mesci, PhD | Innovative Stem Cell Research in Space
This episode is a robust conversation with Pinar Mesci, PhD, the Senior Program Manager for In-Space Manufacturing at Axiom Space. Our discussion includes her postdoctoral work with Alysson Muotri, PhD, at UC San Diego and her ongoing work leading and facilitating space-based research in low-Earth orbit. Previously, Dr Mesci was a project scientist at UC San Diego studying human neurodevelopment using human induced pluripotent stem cells (iPSCs). Her career includes experience in translational and biomedical research with a track record of publications in the fields of neuroscience, stem cells, inflammation, Zika virus and coronavirus infections. Dr. Mesci holds a patent for the development of methods to generate functional human brain organoids. In 2021, she received the International Rett Syndrome Foundation (IRSF) Innovation Award for her work studying the immune interactions in Rett Syndrome using iPSCs. Hosted by Bobby Gordon. This episode was recorded Aug. 8, 2025; information presented was current as of the date of recording.
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October 1, 2025 at 7:27 PM
🔬 Don't miss out on NO-COST virtual tickets to the annual @ucsandiego.bsky.social Sanford Stem Cell Institute symposium Oct. 16-17. 👩🏽‍🔬 Keynote speakers include PhDs Tannishtha Reya, Fred Gage, Andreas Trumpp & retired astronaut/microbiologist Kate Rubins. RSVP @ bit.ly/StemCellSymp...
September 25, 2025 at 9:05 PM
cnn.it/3V6KB2U "Spaceflight activates ‘dark genome’ in human cells," Dr. Catriona Jamieson's recent space-based stem cell research was published this week. #stemcells #regenerativemedicine #NASA #ISS #CNN #cancer #darkgenome #DNA
Spaceflight activates ‘dark genome’ in human cells, researcher says | CNN
Spaceflight makes certain human stem cells age faster, a study finds, furthering the understanding of the possible effects of space exploration on the human body.
cnn.it
September 8, 2025 at 4:54 PM
cnn.it/3V6KB2U "Spaceflight activates ‘dark genome’ in human cells," Dr. Catriona Jamieson's recent space-based stem cell research was published this week. #stemcells #regenerativemedicine #NASA #ISS #CNN #cancer #darkgenome #DNA
Spaceflight activates ‘dark genome’ in human cells, researcher says | CNN
Spaceflight makes certain human stem cells age faster, a study finds, furthering the understanding of the possible effects of space exploration on the human body.
cnn.it
September 8, 2025 at 4:54 PM