Elliot Tucker-Drob
@tuckerdrob.bsky.social
Reposted by Elliot Tucker-Drob
1/ 🚨New paper in Nature Genetics
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic associations with educational fields - Nature Genetics
Genome-wide analyses of 10 educational fields identify 17 associated loci. Analysis of genetic clustering across specializations identifies two key dimensions that show genetic overlap with personalit...
www.nature.com
November 4, 2025 at 10:23 AM
1/ 🚨New paper in Nature Genetics
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Non-paywalled link to my commentary on @vw1234.bsky.social and colleagues new paper in @nature.com rdcu.be/eI2NG
October 1, 2025 at 6:17 PM
Non-paywalled link to my commentary on @vw1234.bsky.social and colleagues new paper in @nature.com rdcu.be/eI2NG
Reposted by Elliot Tucker-Drob
This was a fantastic collaboration with lots of people including @hilarycmartin.bsky.social @jakobgrove.bsky.social, Experts by Experience, and several others who I can't seem to find on this app.
Article: www.nature.com/articles/s41...
Article: www.nature.com/articles/s41...
Polygenic and developmental profiles of autism differ by age at diagnosis - Nature
A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.
www.nature.com
October 1, 2025 at 4:05 PM
This was a fantastic collaboration with lots of people including @hilarycmartin.bsky.social @jakobgrove.bsky.social, Experts by Experience, and several others who I can't seem to find on this app.
Article: www.nature.com/articles/s41...
Article: www.nature.com/articles/s41...
Reposted by Elliot Tucker-Drob
And a very helpful and informative commentary on the paper by @tuckerdrob.bsky.social www.nature.com/articles/d41...
Early- and late-diagnosed autism are genetically distinct
Analyses of symptoms and genomic data indicate that autism that manifests in early childhood is distinct from autism that is diagnosed later in development.
www.nature.com
October 1, 2025 at 4:05 PM
And a very helpful and informative commentary on the paper by @tuckerdrob.bsky.social www.nature.com/articles/d41...
Reposted by Elliot Tucker-Drob
Keynote speakers: @tuckerdrob.bsky.social @foswald.bsky.social Ellen Hamaker
Hands-on workshops by:
@tedmond.bsky.social & @ukuvainik.bsky.social (genomic analyses)
@dirkwulff.bsky.social (LLMs in personality research)
www.ecp22edinburgh.org/programme
Hands-on workshops by:
@tedmond.bsky.social & @ukuvainik.bsky.social (genomic analyses)
@dirkwulff.bsky.social (LLMs in personality research)
www.ecp22edinburgh.org/programme
September 18, 2025 at 3:21 PM
Keynote speakers: @tuckerdrob.bsky.social @foswald.bsky.social Ellen Hamaker
Hands-on workshops by:
@tedmond.bsky.social & @ukuvainik.bsky.social (genomic analyses)
@dirkwulff.bsky.social (LLMs in personality research)
www.ecp22edinburgh.org/programme
Hands-on workshops by:
@tedmond.bsky.social & @ukuvainik.bsky.social (genomic analyses)
@dirkwulff.bsky.social (LLMs in personality research)
www.ecp22edinburgh.org/programme
A deep and thought-provoking lecture that is definitely worth watching all the way through.
My Dobzhansky lecture at BGA: "Theodosius Dobzhansky and the Origins of Radical Behavior Genetics" is publicly available. I talk about the tensions introduced into the field at the difficult border between science using model organisms and human beings. Thanks to BGA for the opportunity.
Sat_208_Dobzhansky_Lecture
Dobzhansky Lecture by Eric Turkheimer
vimeo.com
August 19, 2025 at 12:16 AM
A deep and thought-provoking lecture that is definitely worth watching all the way through.
A few related conversations have been converging on the question of when various trends and observations with respect to personality are genuine. This is a complex issue without a simple answer... A key issue is that personality is best measured using self- or informant ratings... 1/
While I am not entirely convinced this is “real” and not some psychometric equivalent of a vowel shift (and PRS could help find out a bit I think) this it is relevant:
August 18, 2025 at 12:40 AM
A few related conversations have been converging on the question of when various trends and observations with respect to personality are genuine. This is a complex issue without a simple answer... A key issue is that personality is best measured using self- or informant ratings... 1/
Reposted by Elliot Tucker-Drob
Psychiatric Genetics Beyond Heritability: Q&A with Michel Nivard ( @michelnivard.bsky.social )
“We look for genes as a means to an end—biology, epidemiology, and etiology of complex human outcomes.”
www.psychiatrymargins.com/p/psychiatri...
“We look for genes as a means to an end—biology, epidemiology, and etiology of complex human outcomes.”
www.psychiatrymargins.com/p/psychiatri...
Psychiatric Genetics Beyond Heritability: Q&A with Michel Nivard
We look for genes as a means to an end—biology, epidemiology, and etiology of complex human outcomes.
www.psychiatrymargins.com
July 19, 2025 at 1:14 PM
Psychiatric Genetics Beyond Heritability: Q&A with Michel Nivard ( @michelnivard.bsky.social )
“We look for genes as a means to an end—biology, epidemiology, and etiology of complex human outcomes.”
www.psychiatrymargins.com/p/psychiatri...
“We look for genes as a means to an end—biology, epidemiology, and etiology of complex human outcomes.”
www.psychiatrymargins.com/p/psychiatri...
Reposted by Elliot Tucker-Drob
Humbled to receive the BGA's early career award ☺️ Thank you to my brilliant team #MPRGBiosocial, the @maxplanck.de for investing in early career researchers, @mpib-berlin.bsky.social for the excellent environment, and my many mentors incl @kph3k.bsky.social @tuckerdrob.bsky.social #ScienceTeamSport
🏆 @laraffington.bsky.social won the early career award, and Paul Liechtenstein won the Dobzhansky award
July 3, 2025 at 6:20 AM
Humbled to receive the BGA's early career award ☺️ Thank you to my brilliant team #MPRGBiosocial, the @maxplanck.de for investing in early career researchers, @mpib-berlin.bsky.social for the excellent environment, and my many mentors incl @kph3k.bsky.social @tuckerdrob.bsky.social #ScienceTeamSport
Omg 😂. Well played @michelnivard.bsky.social
O, right I promissed JUICE! Not everyone believes in this work, one of the "haters" was very early... In fact @ent3c.bsky.social practically leant over this papers' crib and said: "well that's not going to be a looker."... Someone just as petty as me, but far more organized, kept the receipts 👇
May 20, 2025 at 5:30 PM
Omg 😂. Well played @michelnivard.bsky.social
Reposted by Elliot Tucker-Drob
O, right I promissed JUICE! Not everyone believes in this work, one of the "haters" was very early... In fact @ent3c.bsky.social practically leant over this papers' crib and said: "well that's not going to be a looker."... Someone just as petty as me, but far more organized, kept the receipts 👇
May 20, 2025 at 5:18 PM
O, right I promissed JUICE! Not everyone believes in this work, one of the "haters" was very early... In fact @ent3c.bsky.social practically leant over this papers' crib and said: "well that's not going to be a looker."... Someone just as petty as me, but far more organized, kept the receipts 👇
Reposted by Elliot Tucker-Drob
You will have seen this post by @tedmond.bsky.social on our new GWAS of Personality. He says you should read the paper (you should), I want to write a thread to entice you. Because social media has shredded your attention as it has mine, I promise there is JUICE & BEEF in this thread!
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 5:18 PM
You will have seen this post by @tedmond.bsky.social on our new GWAS of Personality. He says you should read the paper (you should), I want to write a thread to entice you. Because social media has shredded your attention as it has mine, I promise there is JUICE & BEEF in this thread!
Reposted by Elliot Tucker-Drob
Probably the most important paper in personality psych this decade just dropped. 👀 Interesting genetic correlations between other traits (the #1 reason for GWASs on social traits IMO), and evidence of weak but non-zero assortative mating on personality.
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 12:21 PM
Probably the most important paper in personality psych this decade just dropped. 👀 Interesting genetic correlations between other traits (the #1 reason for GWASs on social traits IMO), and evidence of weak but non-zero assortative mating on personality.
Reposted by Elliot Tucker-Drob
🔥🔥🔥 2 years of our lives right there (extremely proud of everyone, I’ll write a thread later)
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 11:53 AM
🔥🔥🔥 2 years of our lives right there (extremely proud of everyone, I’ll write a thread later)
Reposted by Elliot Tucker-Drob
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 10:14 AM
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
Reposted by Elliot Tucker-Drob
PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1
May 20, 2025 at 10:18 AM
PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
Reposted by Elliot Tucker-Drob
Super brief video intro-ing the alpha version(!!) of an free studyguide/book in sequence models and deeplearning in/for genomics.
Alpha version of my new book on ML in Genomics is online!
YouTube video by Michel's Science Speedrun
www.youtube.com
May 16, 2025 at 11:29 AM
Super brief video intro-ing the alpha version(!!) of an free studyguide/book in sequence models and deeplearning in/for genomics.
Reposted by Elliot Tucker-Drob
🚨 I just released the alpha-version of my AI in Genomics textbook! It covers (so far!) sequence language models & deep learning for DNA/RNA/proteins. Check it out: biobook.michel.science
Sequence Language Models & Deep Learning in Genomics
biobook.michel.science
May 12, 2025 at 12:25 PM
🚨 I just released the alpha-version of my AI in Genomics textbook! It covers (so far!) sequence language models & deep learning for DNA/RNA/proteins. Check it out: biobook.michel.science
Reposted by Elliot Tucker-Drob
Lmao it was all a fucking act. I mean, we all knew it, but it’s funny to see his hypocrisy laid out so beautifully.
Exclusive: In his first address to FDA staff on Wednesday, new CBER director Vinay Prasad emphasized his commitment to evidence, his admiration for agency employees, and his desire to serve the American public.
Read more, based on a recording obtained by STAT:
www.statnews.com/2025/05/07/v...
Read more, based on a recording obtained by STAT:
www.statnews.com/2025/05/07/v...
New CBER Director Vinay Prasad praises evidence, FDA reviewers in first speech to staff
The new CBER director struck a humble, self-deprecating, and even earnest tone in his speech to FDA staff.
www.statnews.com
May 8, 2025 at 5:26 PM
Lmao it was all a fucking act. I mean, we all knew it, but it’s funny to see his hypocrisy laid out so beautifully.
Reposted by Elliot Tucker-Drob
We are looking for a scientist passionate about developmental psychology, sociogenomics, and DNA methylation in a cash gift RCT postdocprogram.mpg.de/node/692! 3.5+ yr position in Berlin (until April 30, 2029) integrated into a new Max Planck postdoc program www.mpg.de/en/max-planc... #MPRGBiosocial
Postdoc position | Max Planck Postdoc Program
postdocprogram.mpg.de
March 21, 2025 at 10:33 AM
We are looking for a scientist passionate about developmental psychology, sociogenomics, and DNA methylation in a cash gift RCT postdocprogram.mpg.de/node/692! 3.5+ yr position in Berlin (until April 30, 2029) integrated into a new Max Planck postdoc program www.mpg.de/en/max-planc... #MPRGBiosocial
Reposted by Elliot Tucker-Drob
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
thereader.mitpress.mit.edu
April 8, 2025 at 8:24 PM
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
Reposted by Elliot Tucker-Drob
Out today, our method for comparing multivariate genetic architecture across groups of people, called Genomic Structural Invariance: www.nature.com/articles/s41...
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex - Nature Genetics
Genomic structural invariance, an extension of genomic structural equation modeling, identifies similarities and differences between males and females in the genetic architectures of eight psychiatric...
www.nature.com
March 7, 2025 at 3:21 PM
Out today, our method for comparing multivariate genetic architecture across groups of people, called Genomic Structural Invariance: www.nature.com/articles/s41...
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
Reposted by Elliot Tucker-Drob
Whoa, popular online anon obsessed with race-IQ pseudoscience is actually a fringe researcher doing race-IQ pseudoscience who was just hyping up his own work and lashing out at colleagues. Who could have guessed.
It's finally official and verified: The X user "Cremieux" is ID'd as a guy called Jordan Lasker. Lasker has been LARPing as an expert in genetics on X to promote racist pseudoscience. @sashagusevposts.bsky.social has been calling out his bullshit for ages
March 4, 2025 at 12:35 AM
Whoa, popular online anon obsessed with race-IQ pseudoscience is actually a fringe researcher doing race-IQ pseudoscience who was just hyping up his own work and lashing out at colleagues. Who could have guessed.
Reposted by Elliot Tucker-Drob
I am beyond thrilled that the authors of the MVP GWAS science paper with underflow p values have let me know they are working to address this problem.
To those that always say "why do you care about such extreme p-values" here's a graphic depiction.
To those that always say "why do you care about such extreme p-values" here's a graphic depiction.
February 14, 2025 at 7:32 PM
I am beyond thrilled that the authors of the MVP GWAS science paper with underflow p values have let me know they are working to address this problem.
To those that always say "why do you care about such extreme p-values" here's a graphic depiction.
To those that always say "why do you care about such extreme p-values" here's a graphic depiction.
Reposted by Elliot Tucker-Drob
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
February 14, 2025 at 1:30 PM
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵