Tom Cumming
@tomcumming.bsky.social
PhD student at Institut Pasteur studying commitment to cell death downstream of the caspases in epithelia.
Pinned
Tom Cumming
@tomcumming.bsky.social
· May 21
The effector caspases drive cell death, but their activation can often be survived, so how do cells make this decision? Our new preprint from @levayerr.bsky.social shows that instantaneous caspase activity is important, but past activation has a key role to play!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Tom Cumming
Check out my first #preLight on the work of Sokol's team exploring PCP and mechanosensation! It was so much fun to pick a preprint, read it, write about it, and even get to ask the authors questions directly. I have a feeling this is just the beginning of many more preLight posts to come! 🙌
Stretch it, wound it, pull it: ADIP-Diversin polarizes anyway. Characterization of a new mechanosensitive polarity module 🐸
First #preLight from @alinegrata.bsky.social, highlighting #preprint from Chih-Wen Chu, Satheeja Velayudhan, Sergei Sokol and team:
prelights.biologists.com/highlights/m...
First #preLight from @alinegrata.bsky.social, highlighting #preprint from Chih-Wen Chu, Satheeja Velayudhan, Sergei Sokol and team:
prelights.biologists.com/highlights/m...
Mechanical cues organize planar cell polarity during vertebrate morphogenesis and embryonic wound repair - preLights
Stretch it, wound it, pull it: ADIP-Diversin polarizes anyway. Characterization of a new mechanosensitive polarity module.
prelights.biologists.com
July 4, 2025 at 1:38 PM
Check out my first #preLight on the work of Sokol's team exploring PCP and mechanosensation! It was so much fun to pick a preprint, read it, write about it, and even get to ask the authors questions directly. I have a feeling this is just the beginning of many more preLight posts to come! 🙌
The effector caspases drive cell death, but their activation can often be survived, so how do cells make this decision? Our new preprint from @levayerr.bsky.social shows that instantaneous caspase activity is important, but past activation has a key role to play!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 21, 2025 at 8:52 AM
The effector caspases drive cell death, but their activation can often be survived, so how do cells make this decision? Our new preprint from @levayerr.bsky.social shows that instantaneous caspase activity is important, but past activation has a key role to play!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Tom Cumming
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
www.biorxiv.org
May 12, 2025 at 2:01 PM
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Reposted by Tom Cumming
How oncogenic clones can eliminate their neighbours to take over space ? There are different ways combining growth and interfacial tension induced compaction. Check out our latest preprint led by Léo Valon and Alexis Matamoro-Vidal to learn more about this 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 13, 2025 at 2:53 PM
How oncogenic clones can eliminate their neighbours to take over space ? There are different ways combining growth and interfacial tension induced compaction. Check out our latest preprint led by Léo Valon and Alexis Matamoro-Vidal to learn more about this 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...