Tolga Bozkurt
@tolgaboz.bsky.social
Scientist @Imperial College, host-pathogen interactions, plant immunity, cell biology, autophagy, proteolysis, immune receptors. bozkurtlab.co.uk
Co-founder @ResurrectBio.bsky.social
Co-founder @ResurrectBio.bsky.social
Pinned
Tolga Bozkurt
@tolgaboz.bsky.social
· Sep 6
Validate User
academic.oup.com
Our latest work on how chloroplasts contribute to immunity: Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses url: academic.oup.com/plcell/artic...
Reposted by Tolga Bozkurt
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses (Enoch Lok Him Yuen, Zachary Savage, Vojtěch Pražák, et al) doi.org/10.1093/plce... #PlantScience
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses
Chloroplast tethering to the pathogen interface via membrane contact sites promotes focal callose deposition and strengthens plant immunity.
doi.org
October 16, 2025 at 6:08 PM
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses (Enoch Lok Him Yuen, Zachary Savage, Vojtěch Pražák, et al) doi.org/10.1093/plce... #PlantScience
Reposted by Tolga Bozkurt
Recent paper from @tolgaboz.bsky.social’s group at @imperiallifesci.bsky.social focuses on membrane contact sites between chloroplasts and the pathogen interface and their role in immunity 🎉
Delighted to have helped 🔬
Delighted to have helped 🔬
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses (Enoch Lok Him Yuen, Zachary Savage, Vojtěch Pražák, et al) doi.org/10.1093/plce... #PlantScience
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses
Chloroplast tethering to the pathogen interface via membrane contact sites promotes focal callose deposition and strengthens plant immunity.
doi.org
October 16, 2025 at 7:00 PM
Recent paper from @tolgaboz.bsky.social’s group at @imperiallifesci.bsky.social focuses on membrane contact sites between chloroplasts and the pathogen interface and their role in immunity 🎉
Delighted to have helped 🔬
Delighted to have helped 🔬
Let's keep in touch: How membrane contact sites drive immune responses url: academic.oup.com/plcell/artic...
Let's keep in touch: How membrane contact sites drive immune responses
Inside every cell, a pulsating network of molecular messengers orchestrates life's most critical conversations. While vesicular trafficking facilitates lon
academic.oup.com
October 17, 2025 at 1:06 PM
Let's keep in touch: How membrane contact sites drive immune responses url: academic.oup.com/plcell/artic...
Huge congratulations to Nick Eilmann, our undergrad intern and tutee, for winning two BSPP awards — the Undergraduate Exam Award 2025 and the Undergraduate Project Prize 2025!
September 25, 2025 at 10:38 PM
Huge congratulations to Nick Eilmann, our undergrad intern and tutee, for winning two BSPP awards — the Undergraduate Exam Award 2025 and the Undergraduate Project Prize 2025!
Reposted by Tolga Bozkurt
Just planted in @jcellsci.bsky.social 🌳 😍
An A. thaliana mutant lacking all nine #ATG8 isoforms provides genetic evidence for functional specialization of #ATG8 in plants
forest.biologists.com/landscape/?i...
An A. thaliana mutant lacking all nine #ATG8 isoforms provides genetic evidence for functional specialization of #ATG8 in plants
forest.biologists.com/landscape/?i...
Landscape - The Forest of Biologists
forest.biologists.com
September 11, 2025 at 7:09 AM
Just planted in @jcellsci.bsky.social 🌳 😍
An A. thaliana mutant lacking all nine #ATG8 isoforms provides genetic evidence for functional specialization of #ATG8 in plants
forest.biologists.com/landscape/?i...
An A. thaliana mutant lacking all nine #ATG8 isoforms provides genetic evidence for functional specialization of #ATG8 in plants
forest.biologists.com/landscape/?i...
Reposted by Tolga Bozkurt
Congratulations to all involved 🎉
Delighted to have helped a bit with some FLIM-FRET, and amazed at how much chloroplasts do.
Delighted to have helped a bit with some FLIM-FRET, and amazed at how much chloroplasts do.
Our latest work on how chloroplasts contribute to immunity: Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses url: academic.oup.com/plcell/artic...
Validate User
academic.oup.com
September 7, 2025 at 7:34 AM
Congratulations to all involved 🎉
Delighted to have helped a bit with some FLIM-FRET, and amazed at how much chloroplasts do.
Delighted to have helped a bit with some FLIM-FRET, and amazed at how much chloroplasts do.
Reposted by Tolga Bozkurt
'I feel privileged to do science every day – it is wonderful to be able to follow a passion and be paid for it! It is flexible and absorbing. I would recommend it to everyone.'
In Profile: Caroline Dean
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
In Profile: Caroline Dean
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
September 5, 2025 at 12:03 PM
'I feel privileged to do science every day – it is wonderful to be able to follow a passion and be paid for it! It is flexible and absorbing. I would recommend it to everyone.'
In Profile: Caroline Dean
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
In Profile: Caroline Dean
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
Our latest work on how chloroplasts contribute to immunity: Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses url: academic.oup.com/plcell/artic...
Validate User
academic.oup.com
September 6, 2025 at 5:36 PM
Our latest work on how chloroplasts contribute to immunity: Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses url: academic.oup.com/plcell/artic...
Reposted by Tolga Bozkurt
Many thanks to Dr. Dmitry Lapin for writing a highlight of our collaborative study and sharing it on his lab’s website.
Learn more about coordinated Ca²⁺ influx cascades for quantitative control of plant immunity here:
phoenix-plant.com/highlights-o...
Learn more about coordinated Ca²⁺ influx cascades for quantitative control of plant immunity here:
phoenix-plant.com/highlights-o...
News in plant immunology
Contents Coordinated Ca2+ influx cascades for quantitative control of plant immunity Coordinated Ca2+ influx cascades for quantitative control of plant immunity Written by Dmitry Lapin, J…
phoenix-plant.com
August 29, 2025 at 11:31 AM
Many thanks to Dr. Dmitry Lapin for writing a highlight of our collaborative study and sharing it on his lab’s website.
Learn more about coordinated Ca²⁺ influx cascades for quantitative control of plant immunity here:
phoenix-plant.com/highlights-o...
Learn more about coordinated Ca²⁺ influx cascades for quantitative control of plant immunity here:
phoenix-plant.com/highlights-o...
Big cheers to Edward on his last day with us . Thanks for being an awesome BSPP summer intern — we’ll miss having you around! #BSPP #PlantScience
August 23, 2025 at 10:43 AM
Big cheers to Edward on his last day with us . Thanks for being an awesome BSPP summer intern — we’ll miss having you around! #BSPP #PlantScience
Reposted by Tolga Bozkurt
Loved Naomi Nakayama’s talk-truly original research! #PlantBio2025
July 27, 2025 at 3:32 PM
Loved Naomi Nakayama’s talk-truly original research! #PlantBio2025
Reposted by Tolga Bozkurt
A mesmerizing time-lapse of the Sun in ultraviolet light, captured by the Solar Dynamics Observatory spacecraft over a month.
-Credits: NASA
-Credits: NASA
July 27, 2025 at 4:05 PM
A mesmerizing time-lapse of the Sun in ultraviolet light, captured by the Solar Dynamics Observatory spacecraft over a month.
-Credits: NASA
-Credits: NASA
Reposted by Tolga Bozkurt
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
www.science.org
July 24, 2025 at 6:23 PM
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
Reposted by Tolga Bozkurt
I’m very grateful and excited to start our ARIA-funded project on redesigning plant immunity!
NEWS - Radical approach to improve plant immunity secures funding for Programmable Plants initiative
@philcarella.bsky.social’s group has been awarded ARIA funding for an ambitious research programme which seeks to protect major crops from disease.
www.jic.ac.uk/news/radical...
@philcarella.bsky.social’s group has been awarded ARIA funding for an ambitious research programme which seeks to protect major crops from disease.
www.jic.ac.uk/news/radical...
July 23, 2025 at 1:38 PM
I’m very grateful and excited to start our ARIA-funded project on redesigning plant immunity!
Reposted by Tolga Bozkurt
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
Research Associate in Programmable Plant Immunity at Imperial College London
Apply for the Research Associate in Programmable Plant Immunity role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
www.jobs.ac.uk
July 7, 2025 at 3:01 PM
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
Reposted by Tolga Bozkurt
Thank you to AmirAli Toghani @amiralito.bsky.social, Raoul Frijters, Tolga Bozkurt @tolgaboz.bsky.social, Ryohei Terauchi, and Sophien Kamoun @kamounlab.bsky.social for the wonderful supports!
July 16, 2025 at 3:57 PM
Thank you to AmirAli Toghani @amiralito.bsky.social, Raoul Frijters, Tolga Bozkurt @tolgaboz.bsky.social, Ryohei Terauchi, and Sophien Kamoun @kamounlab.bsky.social for the wonderful supports!
Reposted by Tolga Bozkurt
Poster at #ISMPMI2025 from collaborations with @sainburylab.bsky.social #Proteomics group: P011 ( @isabelmonte.bsky.social ), P073 ( @HeeKungAng group), P086 & P034 (Zipfel group) P101 ( @tolgaboz.bsky.social ) and P130 ( @jonathandgjones.bsky.social and XiaoLin)
July 14, 2025 at 6:42 AM
Poster at #ISMPMI2025 from collaborations with @sainburylab.bsky.social #Proteomics group: P011 ( @isabelmonte.bsky.social ), P073 ( @HeeKungAng group), P086 & P034 (Zipfel group) P101 ( @tolgaboz.bsky.social ) and P130 ( @jonathandgjones.bsky.social and XiaoLin)
Reposted by Tolga Bozkurt
Use of mutants to shut down NLR activity but not localization and structure formation so it can be observed.
www.pnas.org/doi/10.1073/... Dynamic localization of a helper NLR at the plant–pathogen interface underpins pathogen recognition | PNAS
www.pnas.org/doi/10.1073/... Dynamic localization of a helper NLR at the plant–pathogen interface underpins pathogen recognition | PNAS
Dynamic localization of a helper NLR at the plant–pathogen interface underpins pathogen recognition | PNAS
Plants employ sensor–helper pairs of NLR immune receptors to recognize pathogen effectors
and activate immune responses. Yet, the subcellular local...
www.pnas.org
July 15, 2025 at 6:48 AM
Use of mutants to shut down NLR activity but not localization and structure formation so it can be observed.
www.pnas.org/doi/10.1073/... Dynamic localization of a helper NLR at the plant–pathogen interface underpins pathogen recognition | PNAS
www.pnas.org/doi/10.1073/... Dynamic localization of a helper NLR at the plant–pathogen interface underpins pathogen recognition | PNAS
Reposted by Tolga Bozkurt
Unsurprisingly beautiful microscope images from @tolgaboz.bsky.social, which you can browse in this preprint #2025ISMPMI
Tldr; NLRs can target different membrane interfaces, not just the plasma membrane.
www.biorxiv.org/content/10.1... A helper NLR targets organellar membranes to trigger immunity
Tldr; NLRs can target different membrane interfaces, not just the plasma membrane.
www.biorxiv.org/content/10.1... A helper NLR targets organellar membranes to trigger immunity
July 15, 2025 at 6:54 AM
Unsurprisingly beautiful microscope images from @tolgaboz.bsky.social, which you can browse in this preprint #2025ISMPMI
Tldr; NLRs can target different membrane interfaces, not just the plasma membrane.
www.biorxiv.org/content/10.1... A helper NLR targets organellar membranes to trigger immunity
Tldr; NLRs can target different membrane interfaces, not just the plasma membrane.
www.biorxiv.org/content/10.1... A helper NLR targets organellar membranes to trigger immunity
Reposted by Tolga Bozkurt
Happy to share our newest paper fresh from the press. Have a look, how cells prepare to host symbiotic infections. We really appreciate the reviewers comments. Enjoy the microscopy and other experiments by the lead PostDoc Morgane Batzenschlager & collaborators. elifesciences.org/articles/88588
Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in Medicago truncatula
Imaging deep root tissues with a combination of cell-cycle reporters reveals that a cortical cell file traversed by symbiotic bacteria exhibits reduced proliferative potential and enters a prolonged G...
elifesciences.org
July 7, 2025 at 1:07 PM
Happy to share our newest paper fresh from the press. Have a look, how cells prepare to host symbiotic infections. We really appreciate the reviewers comments. Enjoy the microscopy and other experiments by the lead PostDoc Morgane Batzenschlager & collaborators. elifesciences.org/articles/88588
Reposted by Tolga Bozkurt
I'm very pleased to present the @cp-devcell.bsky.social Voices on plant model organism: www.sciencedirect.com/science/arti.... While we appreciate the diversity of plant models, one often questions which model is the "best"?
Exploring the diversity of plant model organisms
Increasing plant genome research, together with advanced transformation technology, enables researchers to address their research questions more effec…
www.sciencedirect.com
June 23, 2025 at 4:18 PM
I'm very pleased to present the @cp-devcell.bsky.social Voices on plant model organism: www.sciencedirect.com/science/arti.... While we appreciate the diversity of plant models, one often questions which model is the "best"?
Reposted by Tolga Bozkurt
It's been a really fun ride to put this Voices together, and huge thanks to all authors contributed: @seedrevolutionlab.bsky.social John Bowman @michaelraissig.bsky.social @philippaborrill.bsky.social Sabeeha Merchant; Feng Qin; Enoch Lok Him Yuen; @tolgaboz.bsky.social; Fang Xie
June 23, 2025 at 4:18 PM
It's been a really fun ride to put this Voices together, and huge thanks to all authors contributed: @seedrevolutionlab.bsky.social John Bowman @michaelraissig.bsky.social @philippaborrill.bsky.social Sabeeha Merchant; Feng Qin; Enoch Lok Him Yuen; @tolgaboz.bsky.social; Fang Xie
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
Research Associate in Programmable Plant Immunity at Imperial College London
Apply for the Research Associate in Programmable Plant Immunity role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
www.jobs.ac.uk
July 7, 2025 at 3:01 PM
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
Reposted by Tolga Bozkurt
Nice paper though it fails to mention very relevant articles on plant #autophagy from @tolgaboz.bsky.social lab. Here's one of them: europepmc.org/article/MED/... #plantblindness
Europe PMCEurope PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
April 11, 2025 at 10:14 AM
Nice paper though it fails to mention very relevant articles on plant #autophagy from @tolgaboz.bsky.social lab. Here's one of them: europepmc.org/article/MED/... #plantblindness
Reposted by Tolga Bozkurt
Very happy to share the final version of our work on the evolution of broad host virulence in Pseudomonas out now @cellhostmicrobe It’s just in time for the holidays 🎄🦠 www.cell.com/cell-host-mi...
A necrotizing toxin enables Pseudomonas syringae infection across evolutionarily divergent plants
Grenz et al. interrogate the Pseudomonas syringae species complex for its capacity to infect evolutionarily divergent host plants. Their results demonstrate that broad host isolates from phylogroup 2 rely on the lipopeptide toxin syringomycin to promote host necrosis and enhance bacterial growth in plants.
www.cell.com
December 19, 2024 at 4:10 PM
Very happy to share the final version of our work on the evolution of broad host virulence in Pseudomonas out now @cellhostmicrobe It’s just in time for the holidays 🎄🦠 www.cell.com/cell-host-mi...